Organic Acids
Medchemexpress LLC Cpn-351 TFA | 912.11 (free base) | 1 MG
CPN-351 TFA (compound 9a) is a pentapeptide that acts as a selective antagonist of human NMUR1. Its antagonistic effect on human NMUR1 is 10 times higher than on NMUR2, making it useful in the study of inflammation.
- Selective antagonist of human NMUR1
- Antagonistic effect is 10 times higher on NMUR1 than NMUR2
- Can be used in the study of inflammation
- pA2 of 7.35 for NMUR1
- Kb of 45 nM for NMUR1
Apexbio Technology LLC Prasugrel hydrochloride 389574-19-0 5mg
Prasugrel hydrochloride (CAS 389574-19-0) is a small molecule inhibitor that targets platelet activation by antagonizing the P2Y12 adenosine diphosphate (ADP) receptor on platelet surfaces By inhibiting this receptor prasugrel impedes ADP-mediated platelet aggregation a critical process in thrombus formation In biochemical assays prasugrel hydrochloride demonstrates an IC50 of 1 8 M for platelet inhibition This compound is utilized in biomedical research to investigate platelet signaling pathways and to model antithrombotic interventions in vitro
Medchemexpress LLC SJ1008030 TFA | 2863634-97-1 | 99.81% | 987.96 | 25 MG
SJ1008030 TFA is a JAK2 PROTAC designed to selectively degrade JAK2. This compound has demonstrated potent inhibitory effects on MHH-CALL-4 cell growth with an IC50 of 5.4 nM, making it a valuable tool for leukemia research.
- Selectively degrades JAK2.
- Inhibits MHH-CALL-4 cell growth with an IC50 of 5.4 nM.
- Useful for leukemia research.
- Degrades JAKs, GSPT1, and IKZF1 in a dose-dependent manner in MHH-CALL-4 cells.
- Dose-dependently degrades JAK2 and GSPT1 protein in xenograft bone marrow SJBALL021415 cells, indicating the inhibition of the JAK-STAT signaling pathway.
Medchemexpress LLC Pemvidutide trifluoroacetate | 98.1% | 3873.35 | C182H275N39O54 | 5 MG
Pemvidutide TFA is a synthetic peptide acting as a dual agonist of the GLP-1 and glucagon receptors. Supplied for research use, it has been investigated for reductions in body weight, liver fat, and serum lipids, and is intended for preclinical and in-vitro studies only.
- Dual GLP-1 and glucagon receptor agonist activity.
- High purity (98.1%).
- Molecular weight 3873.35 Da.
- Provided as the trifluoroacetate salt for peptide stability.
- Available in small milligram sizes for research workflows.
- Store powder at -80°C (up to 2 years) or -20°C (up to 1 year).
Medchemexpress LLC Bio-AMS TFA | 1393881-52-1 | 98.0% | 685.65 | 1 MG
Bio-AMS (TFA) is a potent bacterial biotin protein ligase inhibitor. It exhibits selective activity against *Mycobacterium tuberculosis* (Mtb) and hinders fatty acid and lipid biosynthesis. It is for research use only and not sold to patients.
- Potent bacterial biotin protein ligase inhibitor.
- Selective activity against *Mycobacterium tuberculosis* (Mtb).
- Arrests fatty acid and lipid biosynthesis.
- Excellent antitubercular activity against Mtb H37Rv and MDR/XDR-TB strains with MICs ranging from 0.16 to 0.625 μM.
- Its activity is not affected by changes to the primary carbon source.
- Inhibits growth of Mtb in Mtb-infected mouse macrophages in a concentration-dependent manner (2.5, 5 and 10 μM; 24 h).
- Shows no signs of mitochondrial toxicity.
Medchemexpress LLC Pep42 TFA | 99.6% | 1335.59 | 1 MG
Pep42 TFA is a cyclic peptide ligand of GPR78. It internalizes selectively into highly metastatic human melanoma cells through a receptor-mediated process. This product is for research use only and not sold to patients.
- Cyclic peptide ligand of GPR78
- Selectively internalizes into highly metastatic human melanoma cells
eMolecules 77-92-9 | Citric Acid, anhydrous | Oakwood Chemicals192.123 | C6H8O7 | 99.000 | OC(=O)CC(O)(CC(O)=O)C(O)=O | 50g | 480131649
Citric Acid, anhydrous | Oakwood Chemicals | 77-92-9192.123 | C6H8O7 | 99.000 | OC(=O)CC(O)(CC(O)=O)C(O)=O | 50g | 480131649
Medchemexpress LLC F9170 (TFA) | >98% | 2097.33 | 1 MG
F9170 (trifluoroacetate salt) is an antiviral peptide that corresponds to amino acids 789-803 of the HIV-1 envelope glycoprotein. This product is identified as a laboratory chemical for the manufacture of substances and is strictly for research use only. It must be handled by suitably qualified and experienced scientists in appropriately equipped and authorized facilities.
- Antiviral peptide.
- Corresponds to amino acids 789-803 of the HIV-1 envelope glycoprotein.
- Intended for research use only.
- Suitable for laboratory chemical applications.
- Recommended for handling by experienced personnel.
Medchemexpress LLC LLVK TFA | 585.66 | 25 MG
LLVK TFA is a selective IκB phosphorylation inhibitor. It reduces LPS-induced pro-inflammatory cytokines (IL-1β, IL-6, TNF-α). LLVK TFA is promising for research of inflammatory bowel disease and rheumatoid arthritis.
- Selective IκB phosphorylation inhibitor
- Reduces LPS-induced pro-inflammatory cytokines (IL-1β, IL-6, TNF-α)
- Promising for research of inflammatory bowel disease
- Promising for research of rheumatoid arthritis
Medchemexpress LLC NNC9204-1177 (TFA) | 98.7% | 4570.07 (free base) | 1 MG
NN1177 TFA is a long-acting GLP-1/glucagon receptor co-agonist. It can induce a dose-dependent body weight loss in diet-induced obese (DIO) mice and reduces CYP3A4 mRNA expression and activity in human hepatocytes. It can also reduce liver fat and inflammatory and fibrosis biomarkers in a NASH mouse model.
- Induces dose-dependent body weight loss in diet-induced obese (DIO) mice.
- Reduces CYP3A4 mRNA expression and activity in human hepatocytes.
- Reduces liver fat and inflammatory and fibrosis biomarkers in a NASH mouse model.