Acyl Halides
Apexbio Technology LLC Umeclidinium bromide 869113-09-7 2mg
Umeclidinium bromide (CAS 869113-09-7) is a potent and long-acting antagonist of muscarinic acetylcholine receptors (mAChRs) displaying high affinity for subtypes M1 M5 with Ki values of 0 16 nM 0 15 nM 0 06 nM 0 05 nM and 0 13 nM respectively It selectively targets mAChRs without observable activity at unrelated receptors or channels such as / opioid receptors sodium channels or dopamine transporters In cell-based assays using CHO cells expressing recombinant human mAChRs umeclidinium inhibits acetylcholine-induced calcium flux with pA2 values between 9 6 and 10 6 for M1 M3 receptors In murine models it reverses acetylcholine-driven bronchoconstriction Umeclidinium bromide is broadly applied in research focused on pulmonary disease mechanisms and drug development
Medchemexpress LLC Pinaverium bromide | 53251-94-8 | 99.7% | 591.42 | 25 MG
Pinaverium bromide | 53251-94-8 | 99.7% | 591.42 | 25 MG
Medchemexpress LLC Demecarium bromide | 56-94-0 | 95.0% | 1 ML
Demecarium Bromide (BC-48) is a potent cholinesterase inhibitor known for its apparent affinity (Kiapp) of 0.15 μM. It serves as a glaucoma agent, effective in both normotensive and inherited glaucoma conditions. In vivo studies demonstrate its ability to cause long-term miosis and decrease intraocular pressure.
- Potent cholinesterase inhibitor
- Apparent affinity (Kiapp) of 0.15 μM
- Used as a glaucoma agent
- Causes long-term miosis
- Decreases intraocular pressure (IOP)
![Medchemexpress LLC Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 13-[(2-fluorophenyl)methyl]-5,6-dihydro-9,10-dimethoxy- | 1390654-28-0 | 98.8% | 524.38 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000437181-Logo.png-250.jpg){kind=logo}
Medchemexpress LLC Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 13-[(2-fluorophenyl)methyl]-5,6-dihydro-9,10-dimethoxy- | 1390654-28-0 | 98.8% | 524.38 | 10 MG
Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium, 13-[(2-fluorophenyl)methyl]-5,6-dihydro-9,10-dimethoxy- | 1390654-28-0 | 98.8% | 524.38 | 10 MG
Medchemexpress LLC N-decanoyl-l-homoserine lactone | 177315-87-6 | MFCD11113140 | 99.9% | 255.35 | 50 MG
N-Decanoyl-L-homoserine lactone is a member of the N-acyl-homoserine lactone family. These lactones regulate gene expression in gram-negative bacteria, such as *Escherichia* and *Salmonella*, and are involved in quorum sensing, which is cell-to-cell communication among bacteria. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs and a research focus for the prevention of biofilm formation. This product is also involved in quorum-sensing signal generation.
- Member of the N-acyl-homoserine lactone family
- Regulates gene expression in gram-negative bacteria
- Involved in quorum sensing, cell-to-cell communication among bacteria
- Relevant for the development of new anti-virulence drugs
- Research focus for the prevention of biofilm formation
- Involved in quorum-sensing signal generation
Medchemexpress LLC N-palmitoyl dopamine | 136181-87-8 | 98.9% | 391.59 | C24H41NO3 | 5 MG
N-Palmitoyl dopamine (PALDA) is an endogenous, long-chain fatty acid dopamide used in research on endovanilloid signaling and dopaminergic lipid mediators. It is reported inactive on TRPV1 and displays entourage effects on related endovanilloids. Supplied as a solution for laboratory research use.
c1ccc(C)cc1)C(O)=O)C(O)=O | 500g | 552708738](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000491014.jpg-250.jpg)
eMolecules 32634-66-5 | (-)-Di-p-toluoyl-L-tartaric Acid | Ambeed386.356 | C20H18O8 | 98.000 | Cc1ccc(cc1)C(=O)O[C@H]([C@@H](OC(=O)c1ccc(C)cc1)C(O)=O)C(O)=O | 500g | 552708738
(-)-Di-p-toluoyl-L-tartaric Acid | Ambeed | 32634-66-5386.356 | C20H18O8 | 98.000 | Cc1ccc(cc1)C(=O)O[C@H]([C@@H](OC(=O)c1ccc(C)cc1)C(O)=O)C(O)=O | 500g | 552708738
Medchemexpress LLC N2-Isobutyryl-2'-O-methylguanosine | 63264-29-9 | 99.97% | 367.36 | 1 ML
N2-Isobutyryl-2'-O-methylguanosine is a nucleic acid synthesis intermediate utilized in applications such as antisense oligonucleotides and mRNA modification. It functions as a key monomer for synthesizing 2'-O-methyl oligoribonucleotides, allowing the final product to form stable double strands with complementary RNA and resist degradation by nucleases. It is primarily used in molecular biology research.
- Used for antisense oligonucleotides and mRNA modification.
- Serves as a key monomer for synthesizing 2'-O-methyl oligoribonucleotides.
- Enables stable double strand formation with complementary RNA.
- Resists degradation by nucleases.
- Used in molecular biology research and pre-mRNA splicing mechanisms studies.