Benzenoids
Medchemexpress LLC Larotinib mesylate hydrate | 2097129-93-4 | C26H36ClFN4O11S2 | 50 MG
Larotinib mesylate hydrate is a potent, broad-spectrum, and orally active tyrosine kinase inhibitor (TKI) with EGFR as its primary target, demonstrating an IC50 of 0.6 nM. This compound is intended for research use only.
- Potent broad-spectrum and orally active tyrosine kinase inhibitor
- Primary target is EGFR with an IC50 of 0.6 nM
- Purity of 98.66%
- Appears as a white to off-white solid
- Molecular weight of 699.17
- Soluble in DMSO at 25 mg/mL (35.76 mM)
- Stock solution can be stored at -80°C for 6 months or -20°C for 1 month (sealed, away from moisture)
Selleck Chemical LLC CPI-455 HCl
CPI-455 HCl is a specific KDM5 inhibitor with a half-maximal inhibitory concentration (IC50) of 10 1 nM for full-length KDM5A in enzymatic assays elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with standard chemotherapy or targeted agents
Selleck Chemical LLC BrdU
BrdU (Bromodeoxyuridine) is a nucleoside analog that competes with thymidine for incorporation into DNA and used in the detection of proliferating cells
Medchemexpress LLC Pritelivir mesylate | 1428333-96-3 | C19H22N4O6S3 | 100 MG
Pritelivir mesylate is an inhibitor of the viral helicase-primase complex. It demonstrates antiviral activity both in vitro and in animal models of herpes simplex virus (HSV) infection, effective against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2).
- Inhibits viral helicase-primase complex
- Exhibits antiviral activity against HSV-1 and HSV-2
- IC50 of 0.02 μM against HSV1-2
- For research use only
- Purity of 99.33%
- Appearance is solid
- Color is white to off-white
eMolecules 4-(1H-Pyrrol-1-ylsulfonyl)phenylboronic acid | 913835-90-2 | 5G | Purity: 97%
Combi-Blocks | 4-(1H-Pyrrol-1-ylsulfonyl)phenylboronic acid | 5G | 913835-90-2 | MFCD08689522
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![Apexbio Technology LLC MAP kinase fragment [Multiple species] 1mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000093073.png-250.jpg)
Apexbio Technology LLC MAP kinase fragment [Multiple species] 1mg
MAP kinase fragment is a peptide fragment targeting MAP kinases It is designed to facilitate investigations of cell signaling regulation and enzyme-substrate specificity thereby elucidating kinase activities associated with disease pathways MAP kinase fragment exerts its biological activity primarily through participation in phosphorylation cascades that regulate transcription factors and modulatory proteins Based on these properties MAP kinase fragment holds research potential in studies of cancer and inflammatory disorders
eMolecules 4-(2-(1H-Pyrazol-1-yl)ethoxy)phenylboronic acid | 957061-18-6 | 1G | Purity: 97%
Combi-Blocks | 4-(2-(1H-Pyrazol-1-yl)ethoxy)phenylboronic acid | 1G | 957061-18-6 | MFCD09258754
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Medchemexpress LLC 8-Bromo-cAMP sodium salt | 76939-46-3 | 99.9% | 430.08 | 100 MG
8-Bromo-cAMP sodium salt is a cyclic AMP analog and an activator of cyclic AMP-dependent protein kinase (PKA). It has shown anti-proliferative and apoptotic effects against various cancer cells.
- Enhances reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells.
- Induces apoptosis in esophageal cancer cell line (Eca-109).
- Induces decidualization of human endometrial stromal cells.
- Reduces tumor growth in CT26 tumor mice.
Medchemexpress LLC Hydronopol | 4747-61-9 | 98.09% | 168.28 | 100 G
Hydronopol is a saturated alcohol terpene derivative. It exhibits central inhibitory, anticonvulsant, analgesic, anticholinergic, and antihypertensive activities, making it suitable for research related to neurological and cardiovascular diseases.
- Saturated alcohol terpene derivative
- Central inhibitory activity
- Anticonvulsant activity
- Analgesic activity
- Anticholinergic activity
- Antihypertensive activity
- Used in neurological disease research
- Used in cardiovascular disease research
- Purity 98.09%
- Molecular Formula: C11H20O
- Molecular Weight: 168.28
- CAS Number: 4747-61-9
Medchemexpress LLC ELOVL6-IN-4 | 1170321-92-2 | C20H20F3N3O3S | 1 ML
ELOVL6-IN-4 is a potent, selective, and orally active long chain fatty acid elongase 6 (ELOVL6) inhibitor. It exhibits IC50s of 79 nM and 94 nM for human and mouse ELOVL6, respectively, showing excellent selectivity over other human ELOVL subtypes and mouse ELOVL3. This compound is for research use only.
- Potent, selective, and orally active long chain fatty acid elongase 6 inhibitor
- Inhibits human ELOVL6 with an IC50 of 79 nM
- Inhibits mouse ELOVL6 with an IC50 of 94 nM
- Shows excellent selectivity over ELOVL1, ELOVL2, ELOVL3, and ELOVL5 subtypes
- Potently reduces elongation index in mouse hepatocyte cells H2.35 with an IC50 of 30 nM
- Suppresses elongation index in the liver in mice in vivo
- Purity of 98.36%
![Medchemexpress LLC 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl- | 2160546-07-4 | 100.0% | 377.27 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000364203-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 4-Piperidinamine, 1-[3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazin-6-yl]-4-methyl- | 2160546-07-4 | 100.0% | 377.27 | 5 MG
IACS-13909 is a selective, potent, and orally active SHP2 allosteric inhibitor. It exhibits greater selectivity for SHP2 over other phosphatases, including SHP1. This compound demonstrates antitumor activities and suppresses MAPK pathway signaling in receptor tyrosine kinase (RTK)-dependent cancers.
- Potently suppresses the proliferation of wild-type SHP2 and KYSE-520 cells.
- Suppresses pERK and pMEK levels in wild-type SHP2 and KYSE-520 cells.
- Inhibits the proliferation of parental cells and NCI-H1975 CS cells in a dose-dependent manner.
- Achieved 100% tumor growth inhibition (TGI) in mice studies.
- Functions as a selective SHP2 allosteric inhibitor with an IC50 of 15.7 nM and a Kd of 32 nM.
eMolecules FMOC-6-HYDRAZINOICOTINIC ACID | 444794-69-8 | MFCD03788695 | 1g
AstaTech | FMOC-6-HYDRAZINOICOTINIC ACID | 1g | 112536574 | SC4161 | 95.000 | 444794-69-8 | MFCD03788695 | 375.384 | C21H17N3O4
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Medchemexpress LLC p-SCN-Bn-DOTA | 5MG
p-SCN-Bn-DOTA is a bifunctional chelating agent p-SCN-Bn-DOTA can simultaneously chelate radionuclides and link monoclonal antibody for radioimmunoresearch of tumor[1][2]
eMolecules 2-Chloro-4-(4-fluorophenyl)thiazole | 42445-38-5 | MFCD08446728 | 5g
Chem-Impex | 2-Chloro-4-(4-fluorophenyl)thiazole | 5g | 112762745 | 25682 | | 42445-38-5 | MFCD08446728 | 213.650 | C9H5ClFNS
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