Hydrocarbons
![Aobchem 4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylbenzoic acid | ≥95% | CAS 104224-62-6 | C18H22O3 | 500mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000952542.png-250.jpg)
Aobchem 4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylbenzoic acid | ≥95% | CAS 104224-62-6 | C18H22O3 | 500mg
4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylbenzoic acid | ≥95% | CAS 104224-62-6 | C18H22O3 | 500mg
Medchemexpress LLC DJ-V-159 | 2253744-53-3 | 99.9% | 502.37 | 50 MG
DJ-V-159 is an agonist for G protein-coupled receptor family C group 6 member A (GPRC6A). It activates ERK in HEK-293 cells transfected with GPRC6A and dose-dependently stimulates cAMP production. DJ-V-159 also stimulates insulin secretion in mouse beta-cell MIN-6 cells, similar to the effects of Ocn, a known ligand of GPRC6A, and has been shown to reduce blood glucose levels in wildtype mice.
- Activates ERK in HEK-293 cells transfected with GPRC6A.
- Stimulates cAMP production in GPRC6A expressing HEK-293 cells.
- Stimulates insulin secretion in mouse beta-cell MIN-6 cells.
- Reduces blood glucose levels in wildtype mice.
- For research use only.
Medchemexpress LLC Dichlorobis(tricyclohexylphosphine)palladium(II) | 29934-17-6 | MFCD00191830 | 98.0% | 738.2 g/mol | C36H66Cl2P2Pd | 5 G
Dichlorobis(tricyclohexylphosphine)palladium(II) is a palladium(II) phosphine complex used as a homogeneous catalyst in organic synthesis. It is commonly employed for C-C and C-N cross-coupling reactions and for the carbonylation of chloroarenes under mild conditions, and is supplied as a solid for research use.
- Used as a homogeneous catalyst for C-C and C-N cross-coupling reactions.
- Effective in the carbonylation of chloroarenes under mild conditions.
- High purity suitable for research applications.
- Solid form for straightforward handling and storage.
![Medchemexpress LLC Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl)amino]-N-methyl- | 1513879-21-4 | 99.9% | 352.39 | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000385930-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Acetamide, 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl)amino]-N-methyl- | 1513879-21-4 | 99.9% | 352.39 | 25 MG
BQR-695 is a PI4KIIIβ inhibitor with IC50s of 80 nM for human PI4KIIIβ and 3.5 nM for the *Plasmodium* variant of PI4KIIIβ. For research use only.
- Treatment with 0.5 μM of either KAI407 or BQR695 causes GFP-PHOsh2 to redistribute to the parasite plasma membrane, consistent with depletion of intracellular PI4P upon inhibition of PfPI4K function.
- BQR695 shows no evidence of toxicity against mature red blood cells (RBCs).
- It induces a schizont-stage arrest indistinguishable from that observed in imidazopyrazine-treated parasites and exhibits cross-resistance with the imidazopyrazine-resistant lines.
- DMSO: 50 mg/mL (141.89 mM; requires ultrasonic; hygroscopic DMSO has a significant impact on solubility, use newly opened DMSO).
- Powder: -20°C for 3 years, 4°C for 2 years.
- In solvent: -80°C for 2 years, -20°C for 1 year.
Medchemexpress LLC ETC-159 | 1638250-96-0 | 99.1% | 391.38 | 1 ML
ETC-159 is a potent, orally available PORCN inhibitor that inhibits β-catenin reporter activity with an IC50 of 2.9 nM. It is intended for research use only.
- Inhibits β-catenin reporter activity
- Potent and orally available PORCN inhibitor
- Active in multiple cancer models with high Wnt signaling
- Efficacious in colorectal cancers with R-spondin translocations
- Good oral pharmacokinetics in mice with 100% oral bioavailability
Aobchem 1-(4-Tricyclo[3 3 1 13 7]dec-1-ylphenyl)ethanone | 95% | CAS 38197-47-6 | C18H22O | 250mg
1-(4-Tricyclo[3 3 1 13 7]dec-1-ylphenyl)ethanone | 95% | CAS 38197-47-6 | C18H22O | 250mg
Aobchem 4-Tricyclo[3 3 1 13 7]dec-1-ylbenzaldehyde | 97% | CAS 67116-18-1 | C17H20O | 500mg
4-Tricyclo[3 3 1 13 7]dec-1-ylbenzaldehyde | 97% | CAS 67116-18-1 | C17H20O | 500mg
Aobchem (4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylphenyl)phenylmethanone | 95% | CAS 1312890-73-5 | C24H26O2 | 500mg
(4-Methoxy-3-tricyclo[3 3 1 13 7]dec-1-ylphenyl)phenylmethanone | 95% | CAS 1312890-73-5 | C24H26O2 | 500mg
Aobchem 1-(4-Tricyclo[3 3 1 13 7]dec-1-ylphenyl)ethanone | 95% | CAS 38197-47-6 | C18H22O | 500mg
1-(4-Tricyclo[3 3 1 13 7]dec-1-ylphenyl)ethanone | 95% | CAS 38197-47-6 | C18H22O | 500mg
Medchemexpress LLC FMF-04-159-2 | 2364489-81-4 | 99.5% | 1 ML
FMF-04-159-2 is a potent covalent inhibitor targeting both CDK14 and CDK2, exhibiting IC50s of 39.6 nM and 256 nM respectively in NanoBRET assays. This compound effectively inhibits HCT116 proliferation with an IC50 of 1,144±190 nM.
- Covalent CDK14 and CDK2 inhibitor
- Potent inhibition of HCT116 proliferation
- High solubility in DMSO (≥ 100 mg/mL)
- Comprehensive documentation, including Data Sheet, COA, and SDS, is available
Medchemexpress LLC ETC-159 | 1638250-96-0 | 99.1% | 391.38 | 100 MG
ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM. ETC-159 blocks the secretion and activity of all Wnts and shows robust activity in multiple cancer models driven by high Wnt signaling. It is highly efficacious in molecularly defined colorectal cancers (CRCs) with R-spondin translocations.
- Potent, orally available PORCN inhibitor.
- Inhibits β-catenin reporter activity with an IC50 of 2.9 nM.
- Blocks the secretion and activity of all Wnts.
- Exhibits robust activity in various cancer models driven by high Wnt signaling.
- Highly efficacious in colorectal cancers (CRCs) with R-spondin translocations.
- Inhibits mouse PORCN with an IC50 of 18.1 nM.
- Demonstrates good oral pharmacokinetics in mice with 100% oral bioavailability after a single oral dose of 5 mg/kg.