Hydrocarbons
Medchemexpress LLC Dynole 2-24 | 1416313-72-8 | 99.1% | C24H41N3 | 25 MG
Dynole 2-24 is an indole-based dynamin GTPase inhibitor with an IC₅₀ of 0.56 μM for dynamin I. This compound is non-toxic and demonstrates increased potency against dynamin I and II both in vitro and within cells, with an IC₅₀ (CME) of 1.9 μM. It exhibits a 4.4-fold selectivity for dynamin I. Dynole 2-24 acts as an active in-cell inhibitor of clathrin-mediated endocytosis (CME).
- Indole-based dynamin GTPase inhibitor.
- IC₅₀ of 0.56 μM for dynamin I.
- Nontoxic.
- Increased potency against dynamin I and II in vitro and in cells (IC₅₀(CME)=1.9 μM).
- Shows 4.4-fold selectivity for dynamin I.
- Active in-cell inhibitor of clathrin-mediated endocytosis.
Medchemexpress LLC Pentadecane | 629-62-9 | 10 G
Pentadecane is a floral volatile antimalarial agent with anti-inflammatory, analgesic, and antipyretic activities. It is a colorless to off-white liquid that can inhibit the growth of parasites such as Leishmania and avoid infection of macrophages. Store this product at room temperature for up to 3 years.
- Inhibits growth of parasites such as Leishmania
- Avoids infection of macrophages
- Possesses anti-inflammatory, analgesic, and antipyretic activities
- Ships at room temperature
- Store at room temperature for 3 years
- Store in solvent at -80°C for 2 years, or -20°C for 1 year
- Keep container tightly sealed in a cool, well-ventilated area
- Keep away from direct sunlight and sources of ignition
Medchemexpress LLC 6-(4-(7-(tert-butyl)-5-(4-chloro-3-fluorophenyl)...piperazin-1-yl) nicotinic acid | 2014368-93-3 | MFCD18251438 | 99.4% | 565.04 | C30H30ClFN4O4 | 10 MG
I-287 is an orally active, selective protease-activated receptor 2 (PAR2) inhibitor used in research to modulate Gαq and Gα12/13-mediated signaling. It is supplied as a high-purity small-molecule compound characterized for pharmacology studies in cellular and animal models.
- Selective PAR2 inhibitor.
- Orally active small molecule.
- Acts as a negative allosteric regulator of Gαq and Gα12/13.
- Characterized for modulation of downstream signaling pathways.
- High purity (~99.4%) suitable for research applications.
- Available in research-scale quantities, such as 10 mg.
Medchemexpress LLC Tpi-287 (taxane analogue) | 849213-15-6 | MFCD35060996 | 99.5% | 870.0 g/mol | C46H63NO15 | 5 MG
TPI-287 is a brain-penetrant taxane-class microtubule stabilizer intended for preclinical oncology research. It stabilizes microtubules, shows antineoplastic activity in models of metastatic breast cancer to the brain, and is supplied as a research-grade small molecule for laboratory investigation.
- Blood-brain barrier-permeable microtubule stabilizer.
- Demonstrated reduction of metastatic colonization in brain in preclinical studies.
- High purity (~99.5% by HPLC) for reproducible experimental results.
- Available in small-mass pack sizes suitable for in vitro and in vivo work.
- Chemical formula C46H63NO15; molecular weight 870.0 g/mol.
Medchemexpress LLC Dynole 2-24 | 1416313-72-8 | 99.07% | C24H41N3 | 50 MG
Dynole 2-24 is an indole-based dynamin GTPase inhibitor. It is nontoxic and demonstrates increased potency against dynamin I and II both in vitro and within cells. This compound also exhibits selective inhibition of dynamin I and is an active in-cell inhibitor of clathrin-mediated endocytosis.
- Indole-based dynamin GTPase inhibitor.
- Has an IC50 of 0.56 μM for dynamin I.
- Nontoxic.
- Shows increased potency against dynamin I and II in vitro and in cells (IC₅₀(CME)=1.9 μM).
- Displays 4.4-fold selectivity for dynamin I.
- Functions as an active in-cell inhibitor of clathrin-mediated endocytosis.
Medchemexpress LLC 18-Azido-stearic acid | 1529763-58-3 | C18H35N3O2 | 5 MG
18-Azido-stearic acid is a versatile click chemistry reagent featuring an azide group. It functions as a hydrophobic bioconjugation linker, particularly when utilized with N-Myristoyltransferase, allowing for further modifications via Click-chemistry. It effectively participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules and ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Contains an azide group for click chemistry applications
- Functions as a hydrophobic bioconjugation linker
- Can be further modified via click-chemistry
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Participates in ring strain-promoted alkyne-azide cycloaddition (SPAAC)
Medchemexpress LLC Stearic acid | 57-11-4 | MFCD00002752 | 99.9% | 1 ML
Stearic acid is a long-chain dietary saturated fatty acid that significantly reduces visceral fat by inducing apoptosis of preadipocytes. This compound is valuable for research into cardiovascular and metabolic diseases.
- Significantly reduces visceral fat
- Induces apoptosis of preadipocytes
- Used in cardiovascular and metabolic disease studies
- Increases apoptosis of 3T3L1 preadipocytes
- Decreases expression of cIAP2 and Bcl2
- Can reduce bone mineral density
- Can reduce abdominal fat content
- Can reduce serum glucose concentration
eMolecules 5217-05-0 | ChemScene | 1-Methylcyclopentane-1-carboxylic acid | 100mg | 686121767 | CS-0135257 | MFCD08444320 | 128.171 | C7H12O2
ChemScene | 1-Methylcyclopentane-1-carboxylic acid | 100mg | 686121767 | CS-0135257 | 5217-05-0 | MFCD08444320 | 128.171 | C7H12O2
Aobchem N-methoxy-N-methylcyclopentanecarboxamide | ≥97% | CAS 167303-65-3 | C8H15NO2 | 1g
N-methoxy-N-methylcyclopentanecarboxamide | ≥97% | CAS 167303-65-3 | C8H15NO2 | 1g
Aobchem N-methoxy-N-methylcyclopentanecarboxamide | ≥97% | CAS 167303-65-3 | C8H15NO2 | 25g
N-methoxy-N-methylcyclopentanecarboxamide | ≥97% | CAS 167303-65-3 | C8H15NO2 | 25g
Aobchem N-methoxy-N-methylcyclopentanecarboxamide | ≥97% | CAS 167303-65-3 | C8H15NO2 | 10g
N-methoxy-N-methylcyclopentanecarboxamide | ≥97% | CAS 167303-65-3 | C8H15NO2 | 10g
Medchemexpress LLC Sodium octane-1-sulfonate | 5324-84-5 | 99.9% | 216.27 | 500 G
Sodium octane-1-sulfonate is an ion-pairing agent that can be used as a buffer in biochemical research and HPLC.
- Used as an ion-pairing agent.
- Can be used as a buffer in biochemical research.
- Can be used in HPLC.