Organoheterocyclic compounds
1,3-Dimethyl-2-imidazolidinone 99.0+%, TCI America™
CAS: 80-73-9 Molecular Formula: C5H10N2O Molecular Weight (g/mol): 114.15 MDL Number: MFCD00003188 InChI Key: CYSGHNMQYZDMIA-UHFFFAOYSA-N Synonym: 1,3-dimethyl-2-imidazolidinone,n,n'-dimethylethyleneurea,dimethyl imidazolidinone,n,n'-dimethylimidazolidinone,1,3-dimethylimidazolidone,rhonite 1,dmeu,karbomos tsem,2-imidazolidinone, 1,3-dimethyl,1,3-dimethylethyleneurea PubChem CID: 6661 IUPAC Name: 1,3-dimethylimidazolidin-2-one SMILES: CN1CCN(C)C1=O
2-Methyl-1,3-dithiane, 98%
CAS: 6007-26-7 Molecular Formula: C5H10S2 Molecular Weight (g/mol): 134.255 MDL Number: MFCD00014652 InChI Key: KXROTPXCYDXGSC-UHFFFAOYSA-N Synonym: 1,3-dithiane, 2-methyl,m-dithiane, 2-methyl,2-methyl-m-dithiane,methyl-2 dithiane-1,3,methyl-2 dithiane-1,3 french,acmc-20anrf,2-methyl-1,3-dithian,2-methyl-1,3 dithiane,5-19-01-00053 beilstein handbook reference,2-methyl-1,3-dithiane PubChem CID: 22329 IUPAC Name: 2-methyl-1,3-dithiane SMILES: CC1SCCCS1
2-Amino-4-(2,4-difluorophenyl)thiazole 98.0+%, TCI America™
CAS: 105512-80-9 Molecular Formula: C9H6F2N2S Molecular Weight (g/mol): 212.22 MDL Number: MFCD00472891 InChI Key: HKUPOLYVZQLXKP-UHFFFAOYSA-N Synonym: 4-2,4-difluorophenyl-1,3-thiazol-2-amine,2-amino-4-2,4-difluorophenyl thiazole,4-2,4-difluorophenyl thiazol-2-amine,2-amino-4-2,4-difluorophenyl-1,3-thiazole,4-2,4-difluorophenyl thiazol-2-ylamine,4-2,4-difluoro-phenyl-thiazol-2-ylamine,4-2,4-difluorophenyl-1,3-thiazole-2-ylamine,acmc-1bro0,cbmicro_034355,2-thiazolamine,4-2,4-difluorophenyl PubChem CID: 611370 IUPAC Name: 4-(2,4-difluorophenyl)-1,3-thiazol-2-amine SMILES: NC1=NC(=CS1)C1=C(F)C=C(F)C=C1
4-Amino-2,6-dimethylpyridine 98.0+%, TCI America™
CAS: 3512-80-9 Molecular Formula: C7H10N2 Molecular Weight (g/mol): 122.171 MDL Number: MFCD00130078 InChI Key: ZJXMKPARTVOUAM-UHFFFAOYSA-N PubChem CID: 77047 IUPAC Name: 2,6-dimethylpyridin-4-amine SMILES: CC1=CC(=CC(=N1)C)N
2,4-Pyridinedicarboxylic Acid 98.0+%, TCI America™
CAS: 499-80-9 Molecular Formula: C7H5NO4 Molecular Weight (g/mol): 167.12 MDL Number: MFCD00149413 InChI Key: MJIVRKPEXXHNJT-UHFFFAOYSA-N Synonym: 2,4-pyridinedicarboxylic acid,lutidinic acid,2,4-lutidinic acid,2,4-pyridinedicarboxylicacid, hydrate 1:1,4nrq,pd2,4-carboxypicolinic acid,pubchem16314,pyridine carboxylate, 6a,acmc-1bnb9 PubChem CID: 10365 ChEBI: CHEBI:44737 IUPAC Name: pyridine-2,4-dicarboxylic acid SMILES: OC(=O)C1=CC=NC(=C1)C(O)=O
![3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 98.0+%, TCI America™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-63234-80-0.jpg-250.jpg)
3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 98.0+%, TCI America™
CAS: 63234-80-0 Molecular Formula: C11H15ClN2O Molecular Weight (g/mol): 226.704 MDL Number: MFCD06200813 InChI Key: CMWCQQUYLPYOMY-UHFFFAOYSA-N PubChem CID: 2763079 IUPAC Name: 3-(2-chloroethyl)-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one SMILES: CC1=C(C(=O)N2CCCCC2=N1)CCCl
Apexbio Technology LLC Methylthioadenosine 2457-80-9 25mg
Methylthioadenosine (2457-80-9) is a small-molecule inhibitor targeting high-affinity cyclic AMP phosphodiesterase It is designed to inhibit this enzyme thereby regulating cyclic AMP signaling and related cellular pathways Methylthioadenosine exerts its biological activity primarily through enzyme inhibition In cell-based studies it demonstrates inhibitory activity with a Ki value of 62 M against S49-derived high-affinity cyclic AMP phosphodiesterase Based on these pharmacological properties Methylthioadenosine holds research potential in exploring cellular signaling liver protection and mechanisms underlying hepatic pathologies
Apexbio Technology LLC PD 161570 192705-80-9 5mg
PD 161570 (CAS 192705-80-9) is a small-molecule inhibitor that acts through ATP-competitive binding to suppress the phosphorylation of human FGF-1 receptors In addition to targeting FGF-1R PD 161570 exhibits inhibitory activity against several other tyrosine kinases including PDGFR EGFR and c-Src The compound also interferes with signaling pathways associated with BMP and TGF- Due to its capacity to modulate multiple kinase-driven processes PD 161570 serves as a valuable tool in studies of cell signaling pathways and cellular proliferation mechanisms
Medchemexpress LLC K-252a | 99533-80-9 | 5 MG
K-252a is a staurosporine analog that inhibits protein kinase with IC50 values of 470 nM for PKC, 140 nM for PKA, 270 nM for Ca2+/calmodulin-dependent kinase type II, and 1.7 nM for phosphorylase kinase. It is also a potent inhibitor (IC50 of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, which is a product of the trk protooncogene.
- A staurosporine analog.
- Inhibits protein kinase C (PKC) with an IC50 of 470 nM.
- Inhibits protein kinase A (PKA) with an IC50 of 140 nM.
- Inhibits Ca2+/calmodulin-dependent kinase type II with an IC50 of 270 nM.
- Inhibits phosphorylase kinase with an IC50 of 1.7 nM.
- Potent inhibitor of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk with an IC50 of 3 nM.
- Appears as a white to light yellow solid.
Medchemexpress LLC Mezigdomide | 2259648-80-9 | 99.2% | 25 MG
Mezigdomide (CC-92480) is a cereblon E3 ubiquitin ligase modulating agent (CELMoD) that acts as a molecular glue. It exhibits high affinity to cereblon, leading to potent antimyeloma activity. This product is classified with several hazards including acute oral toxicity, skin and eye irritation, respiratory tract irritation, and suspected reproductive toxicity. It is stable under recommended storage conditions.
- Cereblon E3 ubiquitin ligase modulating agent (CELMoD)
- Acts as a molecular glue
- High affinity to cereblon
- Potent antimyeloma activity
- Effective in CC-5013, CC-4047, and CC-220-resistant cell lines
- Induces loss of Aiolos and Ikaros in cultured PBMCs
- Harmful if swallowed
- Causes skin and serious eye irritation
- May cause respiratory irritation
- Suspected of damaging fertility or the unborn child
Medchemexpress LLC Protodioscin | 55056-80-9 | 1049.20 | 50 MG
Protodioscin is a major steroidal saponin found in Trigonella foenum-graecum Linn. It exhibits a wide range of biological activities, including anti-hyperlipidemia, anti-cancer, sexual effects, and cardiovascular properties. This compound has been shown to improve glucose intolerance and reduce various serum and renal markers of inflammation and disease progression.
- Exhibits anti-hyperlipidemia, anti-cancer, sexual, and cardiovascular effects.
- Cytotoxic against human 293T and HUVEC cell lines (IC50 = 3.22 μM).
- Improves glucose intolerance and reduces serum levels of UA, BUN, Cr, TC, and TG.
- Reduces renal concentrations of IL-1β, IL-6, and TNF-α.
- Ameliorates death rate and neurological deficits in MCAO rats.
- Increases coagulation time by approximately 50%.
- Lowers LDL and increases HDL/LDL ratio.
Medchemexpress LLC Fladrafinil | 90212-80-9 | 98.6% | 25 MG
Fladrafinil (CRL-40,941) is a nootropic compound primarily intended for research use only. It is not sold for patient use.
- Functions as a nootropic
- Suitable for research applications
- Powder stable for 3 years at -20°C
- Powder stable for 2 years at 4°C
- Solution stable for 6 months at -80°C
- Solution stable for 1 month at -20°C
- Appears as a white to off-white solid
Medchemexpress LLC Fladrafinil | 90212-80-9 | 98.6% | 100 MG
Fladrafinil (CRL-40,941) is a nootropic compound. It is intended strictly for research purposes and is not to be sold to patients.
- Nootropic compound
- For research use only
- Not sold to patients
Medchemexpress LLC Cinoxacin | 28657-80-9 | 99.9% | 100 MG
Cinoxacin is a synthetic antimicrobial related to the quinolone class of orally active antibacterial agents. It exhibits antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. It can be used for the research of urinary tract infections and bacterial prostatitis.
- Synthetic antimicrobial
- Related to the quinolone class
- Orally active antibacterial agent
- Inhibits bacterial DNA synthesis
- Antibacterial activity against many gram-negative aerobic bacteria
- Can be used for research on urinary tract infections and bacterial prostatitis
Apexbio Technology LLC PD 161570 192705-80-9 10mg
PD 161570 (CAS 192705-80-9) is a small-molecule inhibitor that acts through ATP-competitive binding to suppress the phosphorylation of human FGF-1 receptors In addition to targeting FGF-1R PD 161570 exhibits inhibitory activity against several other tyrosine kinases including PDGFR EGFR and c-Src The compound also interferes with signaling pathways associated with BMP and TGF- Due to its capacity to modulate multiple kinase-driven processes PD 161570 serves as a valuable tool in studies of cell signaling pathways and cellular proliferation mechanisms