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Choline Chloride An acyl group acceptor Technical Information:Also known as (2-Hydroxyethyl) trimethylammonium chlorideSensitivity: HygroscopicSubstance is listed in Toxic Substance Control Act (TSCA) inventoryAppearance: White crystalline powderDensity : 1.1 g/cm3 at 20 °C (lit.)IUPAC_Name: 2-hydroxy-N,N,N-trimethylethanaminium chloride OR (2-hydroxyethyl)trimethylammonium chlorideMelting Point: 302-305 °C (lit.)(dec.)RTECS Number: KH2975000
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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CAY 10465 is a selective and high-affinity AhR agonist with a Ki of 0.2 nM. It demonstrates no effect on the estrogen receptor (Ki >100000 nM). This compound reduces apolipoprotein A-I (apo A-I) levels in HepG2 cells and inhibits the synthesis of the protein.
Selective and high-affinity AhR agonist
No effect on estrogen receptor
Reduces apolipoprotein A-I levels in HepG2 cells
Inhibits protein synthesis
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Also available in 1 mL, 10 mg, 25 mg, 100 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Cisatracurium besylate (51W89) is a nondepolarizing skeletal muscle relaxant intended for intravenous administration. Purity 98%
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Phenylbiguanide hydrochloride is a research-grade small molecule used as a selective agonist of the 5-HT3 receptor in pharmacology and neuronal signaling studies. It exhibits an EC50 of approximately 3.0 μM and has documented solubility and stability data suitable for laboratory use.
Selective 5-HT3 receptor agonist (EC50 ≈ 3.0 μM).
Chemical identity: CAS 55-57-2; formula C8H12ClN5; molecular weight 213.67 g/mol.
High purity for research applications (COA reports 99.96%).
Soluble in DMSO (≈40 mg/mL); formulations reported for in vivo dosing.
Stable as solid at room temperature; defined solvent storage conditions available.
Suitable for GPCR and neuronal signaling assays and related pharmacology studies.
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Cholesterol 24-hydroxylase-IN-1 is a potent, selective small-molecule inhibitor of cholesterol 24-hydroxylase (CYP46A1) used in biochemical and pharmacological research. The compound is analytically characterized with a defined molecular formula and high purity, enabling use in enzyme inhibition studies and mechanistic investigations.
Potent, selective inhibitor of cholesterol 24-hydroxylase.
Suitable for biochemical and pharmacological research applications.
High purity (>99.5% by LCMS) supporting analytical use.
Molecular weight 313.40 g/mol; formula C17H23N5O.
Supplied as a 5 mg research pack.
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KW 2449 (CAS 1000669-72-6) is a multi-targeted kinase inhibitor with potent activity against FLT3 (IC50 6 6 nM) ABL (14 nM) Aurora kinases (4 nM) and FGFR (48 nM) It inhibits both wild-type and T315I-mutated ABL tyrosine kinase In vitro KW 2449 disrupts proliferation through modulation of distinct signaling pathways it downregulates FLT3/STAT5 phosphorylation and induces G1-phase arrest and apoptosis in FLT3-mutated leukemia cells while promoting G2/M arrest via reduced histone H3 phosphorylation in FLT3 wild-type cells KW 2449 is applied in research investigating kinase-driven leukemias and resistance mechanisms to targeted therapies
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