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This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
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N-Nitroso-N-methyl-4-aminobutyric acid is a tobacco-specific nitrosamine provided as a high-purity research reagent for analytical and toxicological studies. It is intended for laboratory research use only and supplied as a solid; handle with appropriate carcinogen safety precautions.
Tobacco-specific nitrosamine and carcinogen.
Used as an analytical standard and in toxicology studies.
Molecular weight 146.14 g/mol.
Chemical formula C5H10N2O3.
CAS number 61445-55-4.
Reported purity 99.9%.
Supplied as a 100 mg solid.
Certificate of analysis available.
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S-nitroso-N-acetyl-DL-penicillamine (SNAP) is a nitric oxide donor commonly used in biochemical research to provide controlled NO release for studies of vascular function, signaling pathways, and platelet aggregation. It is supplied as a high-purity research chemical for in vitro experiments.
Releases nitric oxide under physiological conditions.
Suitable for studies of vasodilation and platelet aggregation.
High purity (98.8% by HPLC) as confirmed by COA.
Defined molecular properties: 220.25 g/mol, formula C7H12N2O4S.
Available in small research pack sizes for laboratory use.
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Nitroso diisobutylamine-d4 is the deuterium labeled Nitroso diisobutylamine. This organic compound can be used as a tracer or as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Used as a tracer
Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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N-Nitroso-3-azabicyclo[3.3.0]octane-d4 is the deuterium labeled N-Nitroso-3-azabicyclo[3.3.0]octane. It is used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development.
Can be used as a tracer
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Deuteration can impact the pharmacokinetic and metabolic profiles of drugs
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Nitrosobenzene (C6H5NO) is an organic nitroso compound used as a reagent and intermediate in organic synthesis and biochemical research. It functions as a radical scavenger and is used to study oxidative DNA damage and neutrophil respiratory burst reactions.
High purity (>98.0%) reagent grade suitable for research applications.
Molecular weight 107.11 g/mol and formula C6H5NO.
Commonly used as an intermediate for azoxybenzene and azobenzene synthesis.
Useful as a radical scavenger in assays of oxidative DNA damage.
Supplied as a 1 G solid for laboratory use; follow SDS for handling and safety.
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The TL1A protein (VEGI protein) belongs to the tumor necrosis factor (TNF) family and is a receptor for TNFRSF25 and TNFRSF6B TL1A is involved in the activation of NF- B and C-Jun pathways which can be used as a regulator of mucosal immunity and participate in the immune pathway of inflammatory bowel disease (IBD) pathogenesis[1][2] TL1A originates from endothelial cells and inhibits the proliferation of breast cancer epithelial and myeloid tumor cells[3] The human TL1A protein has a transmembrane domain (36-56 a a ) that can be cleaved into membrane-type and soluble peptide fragments TL1A/TNFSF15 Trimer Protein Human (HEK293 His-Flag) is the extracullar part of TL1A protein (D91-L251) produced in HEK293 cells with N-terminal His- and Flag-tag
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Larsucosterol (trimethylamine) is a cholesterol metabolite that functions as a potent liver X receptor (LXR) antagonist. This endogenous regulator decreases lipogenesis and inhibits cholesterol biosynthesis by reducing mRNA levels and inhibiting the activation of SREBP-1.
Potent liver X receptor (LXR) antagonist
Decreases lipogenesis
Inhibits cholesterol biosynthesis
Reduces mRNA levels of cholesterol biosynthesis enzymes
Inhibits activation of SREBP-1
Increases cell proliferation in macrophages
Decreases apoptosis in macrophages
Reduces serum lipid levels in NAFLD models
Protects liver from injury by suppressing hepatic inflammation
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APRIL protein (CD256) is a ligand in the tumor necrosis factor (TNF) family that can induce proliferation regulate tumor cell growth and may participate in mononuclear/macrophage-mediated immune process[1] APRIL protein is produced by myeloid cells and their precursors to accelerate cell maturation and peripheral rupture[2] APRIL protein has been widely used in the study of lymphatic malignancies APRIL protein is a type II membrane protein with cytoplasmic domain hydrophobic transmembrane domain and extracellular domain APRIL/TNFSF13 Trimer Protein Cynomolgus (HEK293 His-Flag-Avi) is produced by HEK293 cells (K112-L250) with N-terminal His Avi and Flag tags
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BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA forming a key ligand-receptor pathway together with TNFSF13/APRIL These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity BAFF/TNFSF13B Trimer Protein Human (HEK293 His-Flag) is the recombinant human-derived BAFF/TNFSF13B protein expressed by HEK293 with N-His N-Flag labeled tag
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Recombinant human APRIL/TNFSF13 trimer produced in HEK293 cells and supplied with a His-Flag tag; designed for in vitro receptor binding and functional studies related to B-cell biology and lymphatic malignancies.
Suitable for receptor binding assays and biochemical characterization.
Trimeric form mimics the native ligand assembly for functional studies.
HEK293 expression supports mammalian folding and glycosylation.
Affinity tags enable straightforward purification and detection.
Optimized for cell signaling and ligand-receptor interaction experiments.
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