Organooxygen compounds
Medchemexpress LLC 2-Phenylethyl isothiocyanate (2-PE ITC) | 2257-09-2 | 98.00% | 163.24 | 100 MG
2-Phenylethyl isothiocyanate is a potent antifungal agent that significantly inhibits spore germination and mycelial growth of *Alternaria alternata* with a minimum inhibitory concentration (MIC) of 1.22 mM. Its antifungal effect against *Alternaria alternata* may involve reducing toxin content and breaking down cell membrane integrity.
- Significantly inhibited spore germination.
- Significantly inhibited mycelial growth.
- Reduces toxin content.
- Breaks down cell membrane integrity.
Medchemexpress LLC Ingenol 3,20-dibenzoate | 59086-90-7 | 99.9% | 556.65 | 5 MG
Ingenol 3,20-dibenzoate | 59086-90-7 | 99.9% | 556.65 | 5 MG
Medchemexpress LLC SAR407899 (hydrochloride) | 923262-96-8 | 99.1% | 280.75 | 5 MG
SAR407899 hydrochloride is a selective, potent, and ATP-competitive ROCK inhibitor. It has an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. It inhibits ROCK-2 more effectively than ROCK-1. This product exhibits potent vasorelaxant activity in various isolated arteries and dose-dependently lowers blood pressure in hypertensive SHRs. It also increases penile length in healthy and diabetic rabbits.
- Selective and potent ROCK inhibitor
- ATP-competitive mechanism of action
- Inhibits MYPTT696 phosphorylation
- Blocks thrombin-induced effects
- Inhibits cell proliferation and migration
- Potent vasorelaxant activity
- Reduces blood pressure
- Increases penile length
Medchemexpress LLC Fadrozole hydrochloride | 102676-31-3 | 99.9% | 259.73 | 5 MG
Fadrozole hydrochloride is a potent, selective, and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. This product is for research use only and is not intended for patient treatment.
- Inhibits aromatase with an IC50 of 6.4 nM
- Inhibits estrogen production in hamster ovarian slices with an IC50 of 0.03 μM
- Prevents the development of both benign and malignant spontaneous mammary neoplasms in female Sprague-Dawley rats
- Slows the spontaneous development of pituitary pars distalis adenomas and reduces the incidence of spontaneous hepatocellular tumors
- Reduces parasite burden in male and female mice and recovers specific cellular immune response in male mice
Medchemexpress LLC Antitumor agent-127 | 3034861-58-7 | 99.09% | 1670.92 | 5 MG
Antitumor agent-127 (compound 1) is a parent macrocyclic peptide that displays nanomolar cell-based binding to ROR1 and relatively good internalization in 786-O and MDA-MB-231 tumor cell lines. It does not induce apoptosis in Mia PaCa-2 cells, a model pancreatic tumor cell line with low cell surface expression of ROR1.
- Displays nanomolar cell-based binding to ROR1.
- Demonstrates good internalization in 786-O and MDA-MB-231 tumor cell lines.
- Does not induce apoptosis in Mia PaCa-2 cells.
Medchemexpress LLC Chlorogenic acid | 327-97-9 | MFCD00003862 | 354.31 | 25 MG
Chlorogenic acid | 327-97-9 | MFCD00003862 | 354.31 | 25 MG
Medchemexpress LLC TG 100572 Hydrochloride | 867331-64-4 | 98.8% | 512.43 | 5 MG
TG 100572 Hydrochloride is a multi-targeted kinase inhibitor that effectively targets receptor tyrosine kinases and Src kinases, making it suitable for various research applications.
- Multi-targeted kinase inhibitor
- Inhibits receptor tyrosine kinases and Src kinases
- Potently inhibits VEGFR1, VEGFR2, FGFR1, FGFR2, and PDGFRβ
- Suppresses vascular endothelial cell proliferation
- Blocks VEGF-induced phosphorylation of extracellular signal-regulated kinase
- Induces apoptosis in rapidly proliferating endothelial cell cultures
Cambridge Isotope Laboratories cis-Chlordane (Alpha) (unlabeled) 0 01 g
cis-Chlordane (Alpha) (unlabeled) 0 01 g
Cambridge Isotope Laboratories PFOS/PFOA Injection Standard Mixture 3 mL
PFOS/PFOA Injection Standard Mixture 3 mL
Medchemexpress LLC Nevanimibe hydrochloride | 133825-81-7 | 99.5% | 458.08 | 5 MG
Nevanimibe hydrochloride is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. It also inhibits ACAT2 with an EC50 of 368 nM. This compound induces cell apoptosis and has the potential for adrenocortical cancer, making it suitable for relevant research.
- Orally active and selective ACAT1 inhibitor (EC50 of 9 nM)
- Inhibits ACAT2 (EC50 of 368 nM)
- Induces cell apoptosis
- Has potential for adrenocortical cancer research
- Solid appearance, white to off-white color
- Stable under recommended storage conditions
Medchemexpress LLC Selachyl alcohol | 593-31-7 | C21H42O3 | 5 MG
Selachyl alcohol is an orally active antihypertensive agent with activities similar to antihypertensive neutral renomedullary lipid (ANRL). It is an alkylglycerol compound found in shark liver oil, possessing properties that reduce lung metastasis. It can be used for cardiovascular disease research.
- Reduces blood pressure in hypertensive mice.
- Induces a slow drop in blood pressure of approximately 60 mm Hg.
- Effectively reduces blood pressure via the gastrointestinal tract.
eMolecules 6456-74-2 | tert-Butyl 2-aminoacetate | Oakwood Chemical | MFCD00038194 | 131.175 | C6H13NO2 | 97.000 | CC(C)(C)OC(=O)CN | 100g | 728133023
tert-Butyl 2-aminoacetate | Oakwood Chemical | 6456-74-2 | MFCD00038194 | 131.175 | C6H13NO2 | 97.000 | CC(C)(C)OC(=O)CN | 100g | 728133023
eMolecules 71432-55-8 | tert-Butyl N,N'-diisopropylcarbamimidate | ChemScene | MFCD22123489 | 200.326 | C11H24N2O | 95.000 | CC(C)N\C(OC(C)(C)C)=N\C(C)C | 5g | 536846607
tert-Butyl N,N'-diisopropylcarbamimidate | ChemScene | 71432-55-8 | MFCD22123489 | 200.326 | C11H24N2O | 95.000 | CC(C)N\C(OC(C)(C)C)=N\C(C)C | 5g | 536846607
Medchemexpress LLC 6PPD-Q-13C6 (6PPD-quinone-13C6) | 2754428-18-5 | C1213C6H22N2O2 | 100 UG
6PPD-quinone-13C6 is a 13C labeled compound, serving as both a tracer and an internal standard for quantitative analysis. It is utilized across various spectroscopic techniques, including Nuclear Magnetic Resonance (NMR), Gas Chromatography-Mass Spectrometry (GC-MS), and Liquid Chromatography-Mass Spectrometry (LC-MS).
- 13C labeled compound
- Functions as a tracer
- Serves as an internal standard for quantitative analysis
- Compatible with NMR, GC-MS, and LC-MS