Organosulfur Compounds
Medchemexpress LLC (R)-IL-17 modulator 4 | 2446804-29-9 | 99.6% | C27H34N6O2 | 25 MG
(R)-IL-17 modulator 4 is the R-configure of IL-17 modulator 4. This compound is a proagent of IL-17 modulator 1, an orally active, highly efficacious IL-17 modulator. It is promising for the research of IL-17A mediated diseases, including inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome.
- Target: IL-17
- Research applications include inflammation, autoimmune diseases, infectious diseases, cancer, and precancerous syndrome
- Appearance: Solid
- Color: Off-white to gray
- Molecular weight: 474.60
- Solubility in DMSO: 100 mg/mL
Medchemexpress LLC GLP-1R modulator L7-028 | 2648317-95-5 | 99.47% | C24H28N2O3 | 50 MG
GLP-1R modulator L7-028 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site.
- Functions as an allosteric modulator
- Enhances GLP-1 binding to GLP-1R
- Acts via a transmembrane site
- Has an EC50 of 11.01 ± 2.73 μM
TARGETMOL CHEMICALS INC METHOTREXATE METABOLITE 50MG
Also available in 10 mg 25 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant. purity: 99%
![Medchemexpress LLC N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide | 476633-98-4 | 99.7% | 373.40 g·mol⁻1 | C22H19N3O3 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000287716.png-250.jpg)
Medchemexpress LLC N-[4-(1H-benzimidazol-2-yl)phenyl]-2,4-dimethoxybenzamide | 476633-98-4 | 99.7% | 373.40 g·mol⁻1 | C22H19N3O3 | 10 MG
Sirtuin modulator 6 is a small-molecule research compound that modulates sirtuin activity and is used in studies of lifespan, metabolic disorders, and neurodegenerative disease. The material is provided as a characterized solid with supporting batch documentation for research use in biochemical and cellular assays.
- High HPLC purity (99.7%).
- Molecular formula C22H19N3O3; molecular weight 373.40 g·mol⁻1.
- CAS registry number 476633-98-4 confirms chemical identity.
- Supplied in small research pack sizes suitable for assay preparation.
- Characterized by batch-specific COA and SDS for safety and quality data.
- Suitable for biochemical and cellular sirtuin pathway studies.
Medchemexpress LLC Sirtuin modulator 1 | 2070015-26-6 | 99.85% | 606.20 | 100 MG
Sirtuin modulator 1 is a compound that acts as a modulator of SIRTl, a homolog of SIRT3. This compound has an EC1.5 of less than 1 μM and was extracted from patent WO 2010071853 A1, Compound No.4.
- Modulator of SIRTl, a homolog of SIRT3
- High purity of 99.85%
- Solid appearance, light yellow to yellow color
- Molecular weight of 606.20
- Soluble in DMSO at 12.5 mg/mL
Medchemexpress LLC Triclabendazole sulfoxide | 100648-13-3 | MFCD09038493 | 98.8% | C14H9Cl3N2O2S | 10MG
Triclabendazole sulfoxide is the primary plasma metabolite of triclabendazole; it shows antiparasitic activity and has been reported to inhibit the ABCG2/BCRP transporter. Supplied for research use, it is typically used in pharmacology and transporter inhibition studies.
- Main plasma metabolite of triclabendazole.
- Exhibits antiparasitic activity.
- Inhibits ABCG2/BCRP transporter.
- Provided as a research-use reagent, not for human use.
- Stable under recommended cold storage conditions for extended periods.
Medchemexpress LLC Nourseothricin (sulfate) | 96736-11-7 | 99.9% | 500 MG
Nourseothricin (sulfate) is a broad-spectrum polycationic antibiotic that destroys the outer membrane of Gram-negative bacteria. It functions by inhibiting protein biosynthesis in prokaryotic cells and significantly suppressing the growth of eukaryotes such as fungi. It is a dominant selective marker for Fonsecaea pedrosoi and can be utilized as a selective marker for a diverse range of organisms, including bacteria, yeast, filamentous fungi, and plant cells.
- Broad-spectrum antibiotic
- Destroys outer membrane of Gram-negative bacteria
- Inhibits protein biosynthesis in prokaryotic cells
- Suppresses growth of eukaryotes such as fungi
- Selective marker for Fonsecaea pedrosoi, bacteria, yeast, filamentous fungi, and plant cells
- Mixture of several Streptothricins, mainly D and F
- Can create channels in the outer membrane of bacteria
![Medchemexpress LLC Pyrazino[1,2-a]benzimidazol-1(2H)-one, 3,4-dihydro-2-[4-[4-(trifluoromethoxy)phenoxy]butyl]- | 2671063-84-4 | 98.0% | C21H20F3N3O3 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260935.png-250.jpg)
Medchemexpress LLC Pyrazino[1,2-a]benzimidazol-1(2H)-one, 3,4-dihydro-2-[4-[4-(trifluoromethoxy)phenoxy]butyl]- | 2671063-84-4 | 98.0% | C21H20F3N3O3 | 10MG
mGluR2 modulator 1 is a research-grade positive allosteric modulator of the metabotropic glutamate receptor 2 (mGluR2), used in in vitro and in vivo pharmacology studies. It is reported to be brain-penetrant and displays potent receptor activity suitable for mechanistic and preclinical research.
- Potent mGluR2 positive allosteric modulator (EC50 ≈ 0.03 μM).
- Brain-penetrant profile suitable for in vivo studies.
- High purity for research applications.
- Soluble in DMSO (50 mg/mL); in vivo vehicle options documented.
- Stable when stored protected from light at recommended temperatures.
- Supplied as a white to off-white solid for handling and formulation.
Medchemexpress LLC Sirtuin modulator 3 5mg | 5mg
Sirtuin modulator 3 (compound 129) is a N-phenyl benzamide derivative acts as a sirtuin modulator[1]
Medchemexpress LLC Sirtuin modulator 1 | 2070015-26-6 | MFCD29924722 | 99.9% | 10 MG
Sirtuin modulator 1 is a small-molecule modulator of SIRT1 (a homolog of SIRT3) reported with an EC1.5 of <1 μM and described in patent WO 2010071853 A1 (Compound No. 4). Supplied as a high-purity solid for research use, it is intended for biochemical and cellular studies of sirtuin activity.
- High reported purity for assay-ready use.
- Molecular formula C31H32ClN5O2S2, molecular weight 606.20 g/mol.
- CAS number 2070015-26-6 for unambiguous identification.
- Reported EC1.5 potency of <1 μM against SIRT1.
- Available in milligram-scale quantities suitable for research.