Phenylpropanoids and polyketides
Sigma Aldrich Fine Chemicals Biosciences alpha-Cyano-4-hydroxycinnamic acid | 28166-41-8 | MFCD00004204 | 10 g
alpha-Cyano-4-hydroxycinnamic acid | Purity: ≥98% | Mol Wt: 189.17 | 28166-41-8 | MFCD00004204 | 10 g
eMolecules 69038-81-9 | 2-Ethoxycinnamic acid | Chem-Impex192.214 | C11H12O3 | 99.000 | CCOc1ccccc1C=CC(O)=O | 5g | 386901291
2-Ethoxycinnamic acid | Chem-Impex | 69038-81-9192.214 | C11H12O3 | 99.000 | CCOc1ccccc1C=CC(O)=O | 5g | 386901291
Medchemexpress LLC 4-chlorocinnamic acid | 1615-02-7 | MFCD00004396 | 99.0% | 182.61 g·mol⁻1 | C9H7ClO2 | 10g
4-Chlorocinnamic acid is a derivative of Cinnamic acid (HY-N0610A) 4-Chlorocinnamic acid inhibits the monophenolase and diphenolase activities of mushroom tyrosinase with IC50 values of 0 477 mM and 0 229 mM respectively 4-Chlorocinnamic acid inhibits the mycelial growth of Colletotrichum gloeosporioides 4-Chlorocinnamic acid exhibits anticonvulsant activity against acute epilepsy induced by pentylenetetrazol[1][2][3][4]
Medchemexpress LLC m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 100 MG
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | CB1140462 | 99.9% | 164.16 | 5 G
2-Hydroxycinnamic acid is a phenolic acid possessing antimicrobial and antioxidant properties. It exhibits antimicrobial activity against Staphylococcus aureus and has shown to not be susceptible to drug resistance. Additionally, 2-Hydroxycinnamic acid demonstrates inhibitory effects on the infection of HIV/SARS-CoV S pseudovirus, with an IC50 of 0.3 mM. It also has neuroprotective and antitumor activities.
- Possesses antimicrobial properties.
- Has antioxidant properties.
- Exhibits antimicrobial activity against Staphylococcus aureus.
- Not susceptible to drug resistance.
- Demonstrates inhibitory effects on the infection of HIV/SARS-CoV S pseudovirus.
- Has neuroprotective activities.
- Has antitumor activities.
Selleck Chemical LLC BLU 451-E1877-5MG
BLU 451 is a central nervous system (CNS)-penetrant wild-type EGFR-sparing covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM It also exhibits a potent anti-tumor efficacy
Medchemexpress LLC 4-Methoxycinnamic acid | 830-09-1 | 178.19 | 1000 G
4-Methoxycinnamic acid is a natural phenylpropanoid detected in *A. preissii*. It is used for research purposes only.
- Detected as a natural phenylpropanoid in *A. preissii*
- Unusual phenylpropanoid involved in phenylphenalenone biosynthesis
- Purity: 99.87%
- Appearance: Off-white to light yellow solid
- Soluble in DMSO
Medchemexpress LLC 3,4-Dimethoxycinnamic acid | 2316-26-9 | 208.21 | 1 G
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. It exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway.
- Attenuates the ethanol-induced apoptosis of ethanol-exposed L-02 cells
- Inhibits the expression levels of Nox4 and p22phox in L-02 cells
- Attenuates ethanol-induced MAPK phosphorylation in L-02 cells
- Decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase
- Downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner
Medchemexpress LLC 2-Methoxycinnamic acid | 6099-03-2 | MFCD00064238 | 178.18 | 100 G
2-Methoxycinnamic acid is a noncompetitive inhibitor of tyrosinase. This product is for research use only and not sold to patients. It is sourced from plants such as Ranunculaceae, Pulsatilla chinensis (Bunge) Regel, and appears as a white to off-white solid.
- Purity of 99.94%
- Molecular weight of 178.18
- Chemical formula C10H10O3
- SMILES: O=C(O)/C=C/C1=CC=CC=C1OC
- Structure classified as phenylpropanoid and simple phenylpropanol
eMolecules 6099-03-2 | 2-Methoxycinnamic acid | Ambeed178.187 | C10H10O3 | 98.000 | COc1ccccc1C=CC(O)=O | 5g | 490558558
2-Methoxycinnamic acid | Ambeed | 6099-03-2178.187 | C10H10O3 | 98.000 | COc1ccccc1C=CC(O)=O | 5g | 490558558
Medchemexpress LLC 2-Hydroxycinnamic acid | 614-60-8 | MFCD00004379 | 98.71% | 164.16 | 100 MG
2-Hydroxycinnamic acid (Standard) serves as the analytical standard for 2-Hydroxycinnamic acid, intended for research and analytical applications. It is a phenolic acid possessing antimicrobial and antioxidant properties. This analytical standard grade compound is commonly employed in qualitative, quantitative, and methodological research experiments, including HPLC, GC, and MS.
- Demonstrates antimicrobial activity against *Staphylococcus aureus* without susceptibility to drug resistance.
- Exhibits inhibitory effects on HIV/SARS-CoV S pseudovirus infection, with an IC50 of 0.3 mM.
- Possesses neuroprotective activity.
- Possesses antitumor activity.
Medchemexpress LLC (E)-Ethyl p-methoxycinnamate | 24393-56-4 | 99.4% | 206.24 | 1 ML
(E)-Ethyl p-methoxycinnamate is a natural product found in Kaempferia galangal with anti-inflammatory, anti-neoplastic, and anti-microbial effects. It acts as an inhibitor of COX-1 and COX-2 enzymes in vitro, with IC50 values of 1.12 μM and 0.83 μM, respectively. The product is intended for research use only and is not sold to patients.
- Natural product sourced from Kaempferia galangal.
- Exhibits anti-inflammatory, anti-neoplastic, and anti-microbial effects.
- Inhibits COX-1 (IC50: 1.12 μM) and COX-2 (IC50: 0.83 μM) in vitro.
- Shows moderate inhibitory activity against α-glucosidase (IC50: 50 μM).
- Inhibits migration and tubular structure formation in HUVECs.
- Exhibits cytotoxicity in various cancer cells.
- Induces apoptosis through caspase-3/7/8/9 activation in cancer cells.
- Inhibits bFGF and heparin-induced angiogenesis.
Medchemexpress LLC p-Coumaric acid-13C3 | 1261170-80-2 | 167.14 | 500 UG
p-Coumaric acid-13C3 is the 13C-labeled p-Coumaric acid, an abundant isomer of cinnamic acid known for its antitumor and anti-mutagenic activities.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Purity of 99.12%.
- Appears as a solid, white to off-white.
Medchemexpress LLC Ozagrel hydrochloride | 78712-43-3 | 99.9% | 50 MG
Ozagrel hydrochloride (OKY-046 hydrochloride) is a highly selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. It exerts anti-platelet aggregation, vasodilation, and anti-inflammatory effects by inhibiting TXA2 production and increasing prostacyclin (PGI2) production. This product is intended for research use only and can be utilized for studies related to ischemic stroke, asthma, and thromboembolic diseases.
- Highly selective and orally active thromboxane A2 (TXA2) synthase inhibitor
- Exerts anti-platelet aggregation effects
- Promotes vasodilation
- Provides anti-inflammatory effects
- Inhibits TXA2 production
- Increases prostacyclin (PGI2) production
- Useful for research in ischemic stroke
- Useful for research in asthma
- Useful for research in thromboembolic diseases