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Phenylpropaniods are organic compounds characterized by having an aromatic ring and a three-carbon propene tail. Polyketides are compounds characterized by having two or more carbonyl functional groups connected with a single carbon atom.
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Puerarin is an isoflavone extracted from Pueraria root, functioning as a 5-HT2C receptor antagonist. It inhibits the dorsal motor nucleus of the vagus (DMV)-vagus nerve pathway, which leads to decreased fat absorption.
Acts as a 5-HT2C receptor antagonist
Inhibits LPS-induced iNOS, COX-2, and CRP protein and mRNA expression
Functions as a novel open-channel blocker of IK1
Alleviates hepatic damage from chronic alcohol administration
Improves early-stage renal damage in diabetic rats
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Puerarin (CAS 3681-99-0) is an isoflavone compound isolated from the root of Pueraria lobata It exerts multiple pharmacological effects primarily through modulation of oxidative stress and inflammatory signaling pathways Puerarin has been reported to enhance myocardial perfusion protect against ischemic injury and regulate glucose and lipid metabolism in preclinical models Additionally it demonstrates neuroprotective properties including mitigation of neuronal damage associated with neurodegenerative conditions Puerarin is widely studied for its potential in cardiovascular metabolic and neurological disease research
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Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice it has significant antitumour activities the mechanisms are related to increased levels of caspase-3 caspase-7 caspase-9 and Bax and reduced levels Bcl-2. purity: 98%
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Puerarin (CAS 3681-99-0) is an isoflavone compound isolated from the root of Pueraria lobata It exerts multiple pharmacological effects primarily through modulation of oxidative stress and inflammatory signaling pathways Puerarin has been reported to enhance myocardial perfusion protect against ischemic injury and regulate glucose and lipid metabolism in preclinical models Additionally it demonstrates neuroprotective properties including mitigation of neuronal damage associated with neurodegenerative conditions Puerarin is widely studied for its potential in cardiovascular metabolic and neurological disease research
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An isoflavonoid with antioxidant activity; scavenges peroxynitrite, nitric oxide radicals, and total ROS (IC50s = 1.36, 1.13, and 6.51 µM, respectively)
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Puerarin (Kakonein), an isoflavones found in the root of Radix puerariae, is a 5-HT2C receptor and benzodiazepine site antagonist. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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