Phenylpropanoids and polyketides
Selleck Chemical LLC Avobenzone S1904-25mg
Avobenzone (Butyl methoxydibenzoylmethane BF2AVB) is an oil soluble ingredient used in sunscreen products to absorb the full spectrum of UVA rays and a dibenzoylmethane derivative
eMolecules 2-CYANO-3-PHENYLPROPIONIC ACID | 5331-42-0 | 5G | Purity: 97%
AstaTech | 2-CYANO-3-PHENYLPROPIONIC ACID | 5G | 5331-42-0 | MFCD00205073
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Medchemexpress LLC 2-methoxycinnamaldehyde | 1504-74-1 | 99.0% | 162.19 g/mol | C10H10O2 | 5 G
2-Methoxycinnamaldehyde is a natural small-molecule aldehyde used for biochemical and cell-based research. It has reported activity including inhibition of topoisomerase I/II and NF-κB signaling, induction of apoptosis, and effects on mitochondrial and lysosomal function. The material is supplied as a white to yellow solid with typical purity near 98.95% and a molecular weight of 162.19 g/mol. Storage recommendations include keeping the solid under nitrogen at -20°C; in solution, store at -80°C for up to 6 months or at -20°C for up to 1 month.
- Research-grade small molecule for biochemical assays.
- Reported biological activities include apoptosis induction and signaling inhibition.
- High chemical purity suitable for analytical and preparative use.
- Solid physical form facilitates handling and storage.
- Storage guidance provided for long-term and in-solution stability.
Medchemexpress LLC 2-methoxycinnamaldehyde | 1504-74-1 | MFCD00007001 | 99.0% | 162.19 g/mol | C10H10O2 | 100 MG
2-methoxycinnamaldehyde is a naturally occurring cinnamaldehyde derivative isolated from Cinnamomum cassia and used as a research reagent. It is reported to inhibit topoisomerase I and II and NF-κB signaling, to cause mitochondrial dysfunction and lysosomal vesiculation, and to induce DNA damage and apoptosis, with reported antitumor activity in preclinical studies.
- Isolated from Cinnamomum cassia.
- Inhibits topoisomerase I and II and NF-κB signaling.
- Causes mitochondrial dysfunction and induces lysosomal vesiculation.
- Leads to DNA damage and apoptosis in cellular models.
- Reported antitumor effects in preclinical studies.
- Available as an analytical standard with high purity for research use.
Pfaltz & Bauer 2 4-Dimethoxycinnamic Acid 97 25G | 6972-61-8
2 4-Dimethoxycinnamic Acid 97 25G | 6972-61-8
Selleck Chemical LLC AMG 487
AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8 0 nM and 8 2 nM respectively
Cayman Chemical OchratoxIn C-13C20 1.2mL
An internal standard for the quantification of ochratoxin C by GC- or LC-MS
eMolecules Salicylsalicylic acid | 552-94-3 | MFCD00020252 | 25g
Combi-Blocks, Inc. | Salicylsalicylic acid | 25g | 603138634 | QF-8026 | 95.000 | 552-94-3 | MFCD00020252 | 258.229 | C14H10O5
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Medchemexpress LLC Myricetin | 529-44-2 | C15H10O8 | 1 ML
Myricetin is a common plant-derived flavonoid with a wide range of activities, including strong anti-oxidant, anticancer, antidiabetic, and anti-inflammatory properties. It is also an autophagy inducer and is for research use only.
- Strong anti-oxidant activity
- Anticancer activity
- Antidiabetic activity
- Anti-inflammatory activity
- Autophagy inducer
Chem-Impex International, Inc. Quercetin dihydrate | MFCD00149487 | 25G
Quercetin dihydrate , MFCD00149487, 25G
Medchemexpress LLC Brepocitinib P-Tosylate | 2140301-96-6 | 99.99% | 561.60 | 1 MG
Brepocitinib P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor. It also inhibits JAK2 and JAK3. This compound is intended for research use only.
- Potently inhibits TYK2/JAK2 mediated IL-12/pSTAT4 and IL-23/pSTAT3.
- Shows good potency against IL6/pStat1 in CD3+ cellular subset.
- Inhibits JAK1/JAK3 driven γ-common chain cytokines like IL-15/pStat5 and IL-21/pSTAT3.
- Inhibits EPO/pSTAT5 (JAK2 homodimer).
- Inhibits IL10/pSTAT3 (TYK2/JAK1) and IL27/pSTAT3 (JAK1/JAK2/TYK2).
- Significantly reduces paw volume increase in animal models of arthritis.
- Involved in clinical trials for various inflammatory and autoimmune conditions.
Medchemexpress LLC Dibenzoylmethane | 120-46-7 | MFCD00003085 | 98.0% | 224.26 | 5 G
Dibenzoylmethane, a minor ingredient in licorice, activates Nrf2 and prevents various cancers and oxidative damage. It is an analog of curcumin that causes dissociation from Keap1 and nuclear translocation of Nrf2. This product is for research use only and not intended for sale to patients.
- Activates Nrf2
- Prevents various cancers and oxidative damage
- Analog of curcumin
- Causes dissociation from Keap1 and nuclear translocation of Nrf2
TARGETMOL CHEMICALS INC SAR405 R enantiomer 5MG
Also available in 1 mL, 1 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes.SAR405 (R enantiomer) is the less active form of SAR405, an inhibitor of PIK3C3/Vps34. Purity 98.04%
Apexbio Technology LLC Ozagrel 82571-53-7 10mg
Ozagrel (CAS 82571-53-7) is a selective inhibitor of thromboxane A synthase an enzyme involved in the conversion of prostaglandin H to thromboxane A a potent mediator of platelet aggregation and vasoconstriction Ozagrel demonstrates high inhibitory potency with an IC of 4 nM indicating strong activity at low concentrations This compound is widely utilized in research to investigate thromboxane-dependent signaling pathways vascular biology and platelet function as well as in studies exploring potential therapeutic interventions targeting thrombotic and cardiovascular disorders