(Rac)-Rivastigmine-d6 is a labelled racemic Rivastigmine. Rivastigmine (ENA 713 free base) is an orally active and potent cholinesterase (ChE) inhibitor, inhibiting butyrylcholinesterase (BChE) and acetylcholinesterase (AChE). It can cross the blood-brain barrier and is a parasympathomimetic or cholinergic agent used in research for mild to moderate Alzheimer's type dementia and Parkinson's disease dementia. Stable heavy isotopes, such as deuterium, incorporated into drug molecules are used as tracers for quantitation during drug development and can influence pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS