Bezafibrate-d6 is the deuterium labeled Bezafibrate, an agonist of PPAR, with EC50s of 50 μM, 60 μM, and 20 μM for human PPARα, PPARγ, and PPARδ, respectively, and 90 μM, 55 μM, and 110 μM for murine PPARα, PPARγ, and PPARδ, respectively. It is known as a hypolipidemic agent.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs
- Stable heavy isotopes incorporated into drug molecules as tracers for quantitation
- For research use only