Pregnenolone-d4 is the deuterium-labeled version of Pregnenolone, a powerful neurosteroid and a primary precursor to various steroid hormones, including steroid ketones. It functions as a signaling-specific inhibitor of the cannabinoid CB1 receptor, thereby inhibiting the effects of tetrahydrocannabinol (THC) that are mediated by these receptors. Additionally, Pregnenolone can safeguard the brain from cannabis intoxication. It also acts as an activator for the TRPM3 channel and can weakly activate TRPM1 channels.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated for potential impact on pharmacokinetic and metabolic profiles of drugs.