Diterpenoids
Medchemexpress LLC Paclitaxel-d5 (benzoyloxy) | 1261254-56-1 | 98.1% | C47H46D5NO14 | 500 UG
Paclitaxel-d5 (benzoyloxy) is the deuterium-labeled Paclitaxel. Paclitaxel is a naturally occurring antineoplastic agent that stabilizes tubulin polymerization. It can cause both mitotic arrest and apoptotic cell death and also induces autophagy. This product is for research use only and not sold to patients.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC HY-N0866 5mg Medchemexpress, 20-Deoxyingenol CAS:54706-99-9 Purity:>98%
Medchemexpress, HY-N0866 5mg 20-Deoxyingenol CAS:54706-99-9 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Docetaxel Trihydrate
Docetaxel (RP56976 NSC 628503) an analog of paclitaxel is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules
Apexbio Technology LLC Phytol 150-86-7 100g
Phytol is a naturally occurring diterpene alcohol derived from chlorophyll metabolism serving as an activator for retinoid X receptors (RXRs) RXRs are nuclear hormone receptors implicated in transcriptional regulation and cellular differentiation through ligand-dependent signaling pathways involving vitamins and hormones Phytol activates RXRs displaying Ki values ranging from 2 3 to 67 2 M In mammals phytol is metabolized to phytanic acid a reaction regulated by peroxisome proliferator-activated receptor (PPAR ) Additionally phytol interacts with GABA A receptors exhibiting sedative and anxiolytic properties and has been investigated as an antischistosomal candidate in animal models
Cayman Chemical 7-acetyl PaclItaxel 10mg
An inhibitor of microtubule depolymerization; inhibits calcium-induced microtubule depolymerization at 10 µM; reduces the growth of J774.2 macrophages (IC50 = ~60 nM)
Medchemexpress LLC 4,4'-sulfonylbis(2-methylphenol) | 16346-97-7 | MFCD00130281 | 97.0% | 278.32 g·mol-1 | C14H14O4S | 25 MG
Topoisomerase IIα-IN-9 is a bisphenol-derived small-molecule inhibitor of human DNA topoisomerase IIα intended for research use. Reported biochemical activity includes Topo II inhibition (IC50 ≈ 571 μM) and cell growth inhibitory activity in K562 and CHO cells (IC50 ≈ 117 μM and 218 μM, respectively). Molecular formula C14H14O4S and molecular weight 278.32 g·mol-1 are provided; consult the Certificate of Analysis for purity and storage conditions.
- Moderate inhibitor of DNA topoisomerase IIα.
- Exhibits cell growth inhibition in selected cell lines.
- Provided as a characterized small molecule with formula and molecular weight.
- Suitable for biochemical assays and cell-based research applications.
- Certificate of Analysis available for purity and handling details.
Medchemexpress LLC (5E,9E,13E)-teprenone | 3796-63-2 | 99.9% | 330.56 g/mol | C23H38O | 10 MG
(5E,9E,13E)-teprenone is a geranylgeranyl-derived small molecule used in research to induce heat shock proteins (HSPs) and to study gastric mucosal protection. Supplied as a high-purity reagent suitable for biochemical and cellular assays.
- High purity (99.9%) suitable for research applications.
- CAS number 3796-63-2 for unambiguous identification.
- Chemical formula C23H38O; molecular weight 330.56 g/mol.
- Supplied as a 10 mg pack for small-scale experiments.
- Recommended storage: 4°C; in solvent: -80°C (6 months) or -20°C (1 month) under nitrogen.
Medchemexpress LLC 7-epi-docetaxel | 153381-68-1 | MFCD15071206 | 98.8% | 807.88 g·mol⁻¹ | C43H53NO14 | 10 MG
7-Epi-docetaxel is an epimeric impurity of docetaxel used as a research compound and microtubule/tubulin inhibitor. Supplied as a solid powder in a 10 mg quantity, it is intended for laboratory research use only and not for human or clinical applications.
- Impurity/epimer of docetaxel used to study tubulin dynamics and cytotoxicity.
- Solid powder formulation suitable for analytical and cell-based research.
- CAS number 153381-68-1 for unambiguous identification.
- Chemical formula C43H53NO14; molecular weight 807.88 g·mol⁻¹.
- High purity (98.8% reported by supplier) for analytical consistency.
- Store powder at -20°C for long term; store solutions at -80°C for long term per handling instructions.
Medchemexpress LLC Resiniferatoxin | 57444-62-9 | 99.8% | 628.71 g/mol | C37H40O9 | 10 MG
Resiniferatoxin is a highly potent, naturally derived agonist of the transient receptor potential vanilloid 1 (TRPV1) ion channel. It is used in laboratory research to ablate or modulate TRPV1-expressing sensory neurons and to study pain signaling, neurobiology, and cardiac sympathetic afferent reflexes. Supplied as a high-purity solid with storage and solvent guidance, it is intended for research use only (not for human use).
- Potent TRPV1 agonist for targeted neuronal ablation and modulation.
- High chemical purity (99.77%) suitable for sensitive assays.
- Molecular weight 628.71 g/mol and formula C37H40O9.
- Stable solid; store protected from light at -20°C; in solution, store at -80°C for long-term stability.
- Soluble in DMSO; in vitro and in vivo vehicle preparation guidance available.
- Supplied in small milligram-scale quantities appropriate for research applications.
Medchemexpress LLC Isophytol | 505-32-8 | MFCD00048380 | 99.7% | 296.53 g/mol | C20H40O | 500 G
Isophytol is a branched-chain terpene alcohol used as an organic reagent and intermediate in biochemical and life-science research. It is a colorless to light-yellow liquid commonly used in organic synthesis, assay development, and fragrance/intermediate applications.
- High purity, 99.7%.
- Liquid physical form; density ~0.841 g/cm3.
- Molecular weight 296.53 g/mol.
- Suitable for organic synthesis and assay development.
- Available in bulk packaging, including 500 g quantities.
Medchemexpress LLC Tanshinone IIA sulfonate sodium | 69659-80-9 | MFCD09028094 | 396.39 | 50 MG
Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, acting as an inhibitor of store-operated Ca2+ entry (SOCE), and is utilized in the treatment of cardiovascular disorders. It is intended for research use only and is not sold to patients.
- Acts as an inhibitor of store-operated Ca2+ entry (SOCE).
- Used to treat cardiovascular disorders.
- Inhibits hypoxia-induced PKG and PPAR-γ downregulation.
- Suppresses TRPC1 and TRPC6 expression and reverses suppressive effects on basal calcium concentration and SOCE in hypoxic PASMCs.
- Inhibits CYP3A4 activity.
- Attenuates scopolamine-induced cognitive dysfunctions and improves the cholinergic system.
- Increases superoxide dismutase activity and decreases oxidative stress markers.
- Alleviates hypoxia-induced changes in chronic hypoxia PH rat model.
- Prevents peritoneal adhesion.