Diterpenoids
Sigma Aldrich Fine Chemicals Biosciences Tanshinone IIA >=97% (HPLC) | 568-72-9 | MFCD00238692 | 25MG
Tanshinone IIA >=97% (HPLC) | Purity: >=97% (HPLC) | Mol Wt: 294.34 | 568-72-9 | MFCD00238692 | 25MG
Medchemexpress LLC HY-N0174 50mg , Cryptotanshinone Cryptotanshinon;Tanshinone c CAS:35825-57-1 Purity:98%
Medchemexpress, HY-N0174 50mg Cryptotanshinone Cryptotanshinon;Tanshinone c CAS:35825-57-1 Formula:C19H20O3 Purity:98% Cryptotanshinone is a potent STAT3 inhibitor with IC 50 of 4.6 μM, and inhibits STAT3 Tyr705 phosphorylation in DU145 prostate cancer cells. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Cryptotanshinone (Tanshinone C) S2285-1g
Cryptotanshinone (Tanshinone C) is a STAT3 inhibitor with IC50 of 4 6 M in a cell-free assay strongly inhibits phosphorylation of STAT3 Tyr705 with a small effect on STAT3 Ser727 but none against STAT1 nor STAT5 Cryptotanshinone induces ROS-dependent autophagy and mitochondria-mediated apoptosis
Medchemexpress LLC Paclitaxel-d5 | 1129540-33-5 | 98.1% | 858.94 | C47H46D5NO14 | 10 MG
Paclitaxel-d5 is a deuterium-labeled analog of paclitaxel supplied as a white to off-white solid for use as a tracer and internal standard in quantitative analytical methods. It stabilizes tubulin polymerization and is intended for research use in NMR, GC-MS, and LC-MS applications.
- High purity (98.1%).
- Molecular weight 858.94 Da.
- White to off-white solid form.
- Soluble in DMSO and DMF; moderately soluble in ethanol.
- Stable storage as powder at -20 °C for long-term retention.
- Designed for use as tracer and internal standard in quantitative assays.
Cayman Chemical Mulberry leaf Phytol 250g
A degradation product of chlorophyll that is converted to phytanic acid, which can accumulate to toxic levels in a number of metabolic disorders; activates RXRs (Kis range from 2.3-67.2 µM) and promotes the activity of PPAR/RXR heterodimers
Enzo Life Sciences Tanshinone IIA (25mg). CAS: 568-72-9
Tanshinone IIA is a diterpenoid naphthoquinone found in the traditional Chinese medicine Tanshen (Salvia sp). It inhibits AP-1 activity by suppressing jun-fos-DNA complex formation (IC50=0.22 µM) and induces apoptosis in a variety of cell lines Purity: ≥93% (HPLC). Solubility: Soluble in DMSO (25mg/ml) or 100% ethanol (5mg/ml). Long Term Storage: +4°C.
Sigma Aldrich Fine Chemicals Biosciences Aphidicolin, Ready Made Solution from Nigrospora sphaerica | 38966-21-1 | 1ml
Aphidicolin, Ready Made Solution from Nigrospora sphaerica | Mol Wt: 338.48 | 38966-21-1 | 1ml
Apexbio Technology LLC Docetaxel 114977-28-5 100mg
Docetaxel (CAS 114977-28-5) is a semisynthetic taxane derivative originally isolated from the European yew (Taxus baccata) As an antineoplastic agent docetaxel disrupts microtubule dynamics by stabilizing tubulin polymerization resulting in cell cycle arrest at mitosis and subsequent apoptosis In both in vitro and in vivo studies docetaxel demonstrates pronounced cytotoxic activity against diverse tumor types such as breast lung ovarian head and neck and gastric cancers Research particularly highlights its enhanced potency against ovarian cancer cell lines compared to paclitaxel cisplatin and etoposide indicating substantial research value in oncology programs
Apexbio Technology LLC Phytol 150-86-7 250g
Phytol is a naturally occurring diterpene alcohol derived from chlorophyll metabolism serving as an activator for retinoid X receptors (RXRs) RXRs are nuclear hormone receptors implicated in transcriptional regulation and cellular differentiation through ligand-dependent signaling pathways involving vitamins and hormones Phytol activates RXRs displaying Ki values ranging from 2 3 to 67 2 M In mammals phytol is metabolized to phytanic acid a reaction regulated by peroxisome proliferator-activated receptor (PPAR ) Additionally phytol interacts with GABA A receptors exhibiting sedative and anxiolytic properties and has been investigated as an antischistosomal candidate in animal models
Sigma Aldrich Fine Chemicals Biosciences Aphidicolin from Nigrospor5MG
Aphidicolin from Nigrospor5MG
Cayman Chemical 10-acetyl Docetaxel 100mg
A derivative of paclitaxel and an inhibitor of microtubule depolymerization; inhibits calcium-induced depolymerization of calf brain MTP in a cell-free assay at 20 µM; cytotoxic to J774.2 cells (EC50 = 0.05 µM)
Cayman Chemical -AphIdIcolIn 5mg
A natural tetracyclic diterpene with antiviral activity against herpes simplex; a cell-permeable, reversible inhibitor of DNA replication in eukaryotic cells, specifically blocking the activity of DNA polymerases α, δ, and ε when used at low micromolar levels.