Diterpenoids
Medchemexpress LLC Nab-Paclitaxel 25mg | 25mg
Nab-Paclitaxel (Nanoparticle albumin-bound Paclitaxel) is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015) Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug Nab-Paclitaxel is a solvent-free taxane with higher response rates and improved tolerability Nab-Paclitaxel displays less toxicity and greater antitumor activity Nab-Paclitaxel is more readily available for tumor cell uptake in three rhabdomyosarcoma seven neuroblastoma cell lines and one ostersarcoma cell line Nab-Paclitaxel can be studied in cancer research for example breast cancer and solid tumors (The product specifications below only indicate the effective content of Paditaxel the actual albumin quality depends on the batch the ratio of each ingredient in this product is Paditaxel albumin -1 7 1 11)[1][2]
Apexbio Technology LLC Paclitaxel (Taxol) 33069-62-4 500mg
Paclitaxel (Taxol) is a diterpenoid alkaloid initially isolated from the bark of Taxus brevifolia It exhibits antitumor activity primarily by disrupting microtubule dynamics Mechanistically paclitaxel binds tubulin and promotes microtubule polymerization thus stabilizing microtubules and inhibiting their depolymerization This mechanism impairs normal mitotic spindle formation arrests cells in G2-M phase of the cell cycle and induces apoptotic cell death Paclitaxel is extensively employed in biomedical research for investigating antineoplastic mechanisms and testing therapeutic interventions targeting various cancers such as ovarian breast head and neck and lung carcinoma
Abcam Myricetin, irreversible Tr x R inhibitor, 5MG
MW 318.24 g/mol, Purity >97%. Directly inhibits MEK, JAK1, Akt and MKK4 kinase activity. Able to inhibit cytochrome P450 3A4 and 2C9 (IC₅₀ = 7.81 and 13.5 μM, respectively). .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Myricetin, irreversible Tr x R inhibitor, 25MG
MW 318.24 g/mol, Purity >97%. Directly inhibits MEK, JAK1, Akt and MKK4 kinase activity. Able to inhibit cytochrome P450 3A4 and 2C9 (IC₅₀ = 7.81 and 13.5 μM, respectively). .
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC Paclitaxel S1150-1g
Paclitaxel is a microtubule polymer stabilizer with IC50 of 0 1 pM in human endothelial cells Paclitaxel can cause both mitotic arrest and apoptotic cell death Paclitaxel also induces autophagy
Selleck Chemical LLC 10-deacetyl-paclitaxel S3933-5mg
10-deacetyl-paclitaxel (10-DAT Deacetyl Paclitaxel) is a semi-synthetic precursor of Paclitaxel
Selleck Chemical LLC Docetaxel S1148-250mg
Docetaxel an analog of paclitaxel is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules
Sigma Aldrich Fine Chemicals Biosciences Docetaxel purum, >=97.0% (HPLC) | 114977-28-5 | MFCD00800737 | 25MG
Docetaxel purum, >=97.0% (HPLC) | Purity: >=97.0% (HPLC) | Mol Wt: 807.88 | 114977-28-5 | MFCD00800737 | 25MG
Selleck Chemical LLC Docetaxel Trihydrate
Docetaxel (RP56976 NSC 628503) an analog of paclitaxel is an inhibitor of depolymerisation of microtubules by binding to stabilized microtubules
Apexbio Technology LLC Paclitaxel (Taxol) 33069-62-4 100mg
Paclitaxel (Taxol) is a diterpenoid alkaloid initially isolated from the bark of Taxus brevifolia It exhibits antitumor activity primarily by disrupting microtubule dynamics Mechanistically paclitaxel binds tubulin and promotes microtubule polymerization thus stabilizing microtubules and inhibiting their depolymerization This mechanism impairs normal mitotic spindle formation arrests cells in G2-M phase of the cell cycle and induces apoptotic cell death Paclitaxel is extensively employed in biomedical research for investigating antineoplastic mechanisms and testing therapeutic interventions targeting various cancers such as ovarian breast head and neck and lung carcinoma
Apexbio Technology LLC Resiniferatoxin 1mg
Resiniferatoxin (CAS 57444-62-9) is a potent selective agonist of the transient receptor potential vanilloid 1 (TRPV1) channel derived from plant sources By activating TRPV1 it induces sustained calcium influx in TRPV1-expressing sensory neurons leading to their desensitization or ablation In animal studies resiniferatoxin has been shown to induce long-lasting elimination of TRPV1-positive primary sensory afferents and blunt associated neural reflexes including those mediating cardiac sympathetic input Resiniferatoxin is widely used in research to investigate pain pathways sensory neuron function and neurogenic inflammation