Diterpenoids
Medchemexpress LLC Dihydrotanshinone I | 87205-99-0 | 278.30 | 5 MG
Dihydrotanshinone I is a natural compound extracted from *Salvia miltiorrhiza Bunge*. This compound has been extensively used for treating cardiovascular diseases and demonstrates an entry-blocking effect against MERS-CoV.
- Extracted from *Salvia miltiorrhiza Bunge*
- Used for treating cardiovascular diseases
- Exhibits entry-blocking effect for MERS-CoV
- Attenuates atherosclerosis in ApoE-/- mice
- Inhibits LOX-1, NOX4, and NF-κB expression in aorta
- Improves cardiac function and reduces infarct size in myocardial ischemia-reperfusion rats
- Induces caspase-dependent apoptosis and autophagy in colon cancer cells
- Potentially a safe, high-throughput screening compound for MERS-CoV entry inhibitors
- Purity: 99.57%
- Appearance: Solid, brown to red
TARGETMOL CHEMICALS INC DIHYDROTANSHINONE I 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Dihydrotanshinone I (DHTS) is a natural compound extracted from Salvia miltiorrhiza Bunge used for treating of cardiovascular diseases. purity: 99%
TARGETMOL CHEMICALS INC Cucurbitacin IIA 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 1. Cucurbitacin IIA (Dihydrocucurbitacin Q1) can induce apoptosis and enhance autophagy , contributes to the anti-inflammatory activity of Cucurbitacin IIA against inflammation-related diseases. 2. Cucurbitacin IIA is a novel class of anti-cancer drug in suppression of cancer cell expansion by disrupting the actin cytoskeleton and directing the cell to undergo PARP-mediated apoptosis through the inhibition of survivin downstream of JAK2/STAT3. Purity 98.62%
Medchemexpress LLC Tanshinone IIA anhydride | 61077-78-9 | 310.34 | 5 MG
Tanshinone IIA anhydride is a potent and irreversible human carboxylesterase (CE) inhibitor. It has Ki values of 1.9 nM for human CE1 and 1.4 nM for the human intestinal CE (hiCE).
- Potent and irreversible human carboxylesterase (CE) inhibitor.
- Ki values of 1.9 nM for human CE1.
- Ki values of 1.4 nM for human intestinal CE (hiCE).
Medchemexpress LLC Isotanshinone IIA | 20958-15-0 | 1 MG
Isotanshinone IIA is an abietane-type diterpene metabolite. It functions as a non-competitive inhibitor of Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 of 11.4 μM. This compound appears as an orange to orange-red solid and is intended for research use only.
- High purity: 98.0%
- IC50: 11.4 μM for PTP1B
- Molecular weight: 294.34
- Chemical formula: C19H18O3
- Appearance: Solid
- Color: Orange to orange-red
- Structure classification: Quinones, Naphthalene Quinones
- Initial source: Plants Leguminosae Samanea saman (Jacq.) Merr., Plants Labiatae
- Solubility in DMSO: 3 mg/mL (10.19 mM)
Medchemexpress LLC Tanshinone I | 568-73-0 | 98.8% | 276.29 | 100 MG
Tanshinone I is an inhibitor of type IIA human recombinant sPLA2 and rabbit recombinant cPLA2. It demonstrates anti-inflammatory activity in rat carrageenan-induced paw oedema and adjuvant-induced arthritis. It is for research use only.
- Inhibits type IIA human recombinant sPLA2 and rabbit recombinant cPLA2
- Shows anti-inflammatory activity in animal models
- For research use only
Selleck Chemical LLC Cryptotanshinone (Tanshinone C) S2285-1g
Cryptotanshinone (Tanshinone C) is a STAT3 inhibitor with IC50 of 4 6 M in a cell-free assay strongly inhibits phosphorylation of STAT3 Tyr705 with a small effect on STAT3 Ser727 but none against STAT1 nor STAT5 Cryptotanshinone induces ROS-dependent autophagy and mitochondria-mediated apoptosis
Medchemexpress LLC HY-N0174 50mg , Cryptotanshinone Cryptotanshinon;Tanshinone c CAS:35825-57-1 Purity:98%
Medchemexpress, HY-N0174 50mg Cryptotanshinone Cryptotanshinon;Tanshinone c CAS:35825-57-1 Formula:C19H20O3 Purity:98% Cryptotanshinone is a potent STAT3 inhibitor with IC 50 of 4.6 μM, and inhibits STAT3 Tyr705 phosphorylation in DU145 prostate cancer cells. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Cryptotanshinone >=98% (HPLC) | 35825-57-1 | MFCD07636810 | 5MG
Cryptotanshinone >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 296.36 | 35825-57-1 | MFCD07636810 | 5MG
Sigma Aldrich Fine Chemicals Biosciences Tanshinone IIA >=97% (HPLC) | 568-72-9 | MFCD00238692 | 25MG
Tanshinone IIA >=97% (HPLC) | Purity: >=97% (HPLC) | Mol Wt: 294.34 | 568-72-9 | MFCD00238692 | 25MG
Medchemexpress LLC Tanshinone I | 568-73-0 | MFCD00210563 | 98.8% | 276.29 g/mol | C18H12O3 | 10 MG
Tanshinone I is a natural diterpenoid research standard used as a phospholipase inhibitor and analytical reference for biochemical and preclinical studies. It inhibits human type IIA secreted phospholipase A2 (sPLA2) (IC50 = 11 μM) and rabbit cytosolic phospholipase A2 (cPLA2) (IC50 = 82 μM), and is supplied as a high-purity solid for laboratory use.
- Natural diterpenoid research standard for biochemical assays.
- Inhibits sPLA2 (human type IIA) and cPLA2 (rabbit) with reported IC50 values.
- High purity suitable for analytical and research applications.
- Supplied as a solid for flexible formulation and storage.
- Commonly used in studies of inflammation and cardiovascular pathways.
![Medchemexpress LLC Sodium 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonate | 69659-80-9 | MFCD09028094 | 99.8% | 396.4 g/mol | C19H17NaO6S | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000295618.png-250.jpg)
Medchemexpress LLC Sodium 1,6,6-trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonate | 69659-80-9 | MFCD09028094 | 99.8% | 396.4 g/mol | C19H17NaO6S | 10 MG
Tanshinone IIA sulfonate sodium is the sodium sulfonate derivative of tanshinone IIA. It is a water-soluble small molecule reported to inhibit store-operated Ca2+ entry (SOCE) and is used in research on cardiovascular disorders and calcium-signaling pathways.
- Water-soluble sodium sulfonate derivative suitable for aqueous assays.
- Reported inhibitor of store-operated Ca2+ entry (SOCE).
- Applicable to cardiovascular and calcium-signaling research models.
- Characterized chemical identifiers: formula C19H17NaO6S and molecular weight 396.4 g/mol.
- High reported purity (≈99.8%) for research applications.