Quinone and hydroquinone lipids
Cayman Chemical PentnoIc AcId-d9 50mg
An internal standard for the quantification of pentanoic acid by GC- or LC-MS
Medchemexpress LLC MAIT-203 (acetate) | 99.1% | 2577.90 | 25 MG
MAIT-203 acetate is a cyclopentyalanin-derived peptidomimetic that potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4), but not APC-Sam68 or APC-striatin interactions. It binds APC-ARM with a Ki value of 0.015 μM and a Kd value of 0.036 μΜ. This compound significantly represses the migration and invasion of colorectal cancer cells.
- Potently inhibits APC-Asef interaction
- Binds APC-ARM with a Ki value of 0.015 μM and a Kd value of 0.036 μΜ
- Significantly represses migration and invasion of colorectal cancer cells
- Reduces Asef-APC interaction in HEK293T cells
- Attenuates SW480 and HCT116 cell migration
- Decreases the active form of CDC42
Medchemexpress LLC Poneratoxin acetate | 137084-94-7 | 2756.35 (free base) | 5 MG
Poneratoxin acetate is the acetate salt form of Poneratoxin. It functions as a neurotoxic peptide and modulator for voltage-gated sodium channels (NaV), particularly NaV1.6 and NaV1.7. This compound lowers the voltage threshold for activation, inhibits the inactivation of channels, and enhances neuronal excitability, contributing to the transmission of pain signals.
- Acts as a modulator for voltage-gated sodium channels (NaV)
- EC50 values of 97 nM for NaV1.6 and 2.3 μM for NaV1.7
- Lowers the voltage threshold for activation
- Inhibits the inactivation of channels
- Enhances the excitability of neurons
- Leads to the transmission of pain signals
- Solid with a white color
- For research use only
Alkali Scientific CellPro™ 100X Vitamin solution, 100ml, 10/Case
Growth supplement for cell culture medium. Supplement serum- and protein-free media with CellPro™ 100X Vitamin Solution.
Medchemexpress LLC Vitamin K5 hydrochloride | 130-24-5 | 50 MG
Vitamin K5 hydrochloride acts as a photosensitizer and antimicrobial agent, specifically inhibiting PKM2 and inducing apoptosis in colon 26 cells. It finds use in research concerning infection and cancer, and as a preservative for various products.
- Acts as a photosensitizer and antimicrobial agent
- Functions as a specific PKM2 inhibitor
- Induces apoptosis in colon 26 cells
- Can be used for infection and cancer research
- Suitable as a preservative for pharmaceuticals, foods, and beverages
- Increases antibacterial effects of UVA irradiation on various bacteria (e.g., *Escherichia coli*, *Pseudomonas aeruginosa*, *Staphylococcus aureus*)
- Generates superoxide anion radical and hydroxyl radical
- Dose-dependently inhibits cellular glucose consumption and lactate production
- Suppresses proliferation of colon 26 cells
- Increases caspase-3 activity in colon 26 cells
Medchemexpress LLC Sifuvirtide acetate | 99.8% | 4727.98 | 25 MG
Sifuvirtide acetate is a potent HIV fusion inhibitor. It inhibits HIV-1 mediated cell fusion in a dose-dependent manner and is highly potent against infection by primary and laboratory-adapted HIV-1 isolates of multiple genotypes. This product can be used in the research of anti-HIV drugs.
- Potent HIV fusion inhibitor
- Inhibits HIV-1 mediated cell fusion in a dose-dependent manner
- Highly potent against infection by primary and laboratory-adapted HIV-1 isolates of multiple genotypes
- Used for anti-HIV drug research
Medchemexpress LLC Semax acetate | 2828433-33-4 | 99.39% | 873.97 | 5 MG
Semax acetate is a BBB-penetrable adrenocorticotropic hormone-like peptide that can form stable complexes with Cu2+. It is a synthetic peptide analog of Adrenocorticocorticotropic hormone (ACTH) (4-10). Semax acetate exhibits immunomodulatory, nootropic, and neuroprotective activities and is used in the research of central nervous system diseases such as Alzheimer's disease and cerebral ischemia.
- BBB-penetrable adrenocorticotropic hormone-like peptide
- Forms stable complexes with Cu2+
- Synthetic peptide analog of ACTH (4-10)
- Possesses immunomodulatory activity
- Exhibits nootropic activity
- Demonstrates neuroprotective activity
- Used in research for central nervous system diseases like Alzheimer's and cerebral ischemia
Medchemexpress LLC HY-101445 500mg Medchemexpress, Trolox CAS:53188-07-1 Purity:98%
Medchemexpress,HY-101445 500mg Trolox CAS:53188-07-1 Formula:C14H18O4 Troloxa is a cell-permeable and water-soluble vitamin E analogue and is a powerful antioxidant. Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC (rel)-AR234960 | 1408311-94-3 | HY-120006A | 98.95% | 555.62 | 10 MG
(rel)-AR234960 is a selective and competitive agonist of the G protein-coupled receptor MAS. It activates the downstream ERK1/2 signaling pathway, leading to the expression of connective tissue growth factor (CTGF) and its downstream collagen subtype genes. This compound promotes collagen synthesis in cardiac fibroblasts via the MAS-ERK1/2-CTGF pathway and exacerbates extracellular matrix remodeling. It regulates the expression of cardiac fibrosis-related genes and can be utilized in heart failure research.
- Selective and competitive MAS receptor agonist
- Activates ERK1/2 signaling pathway
- Induces CTGF and collagen gene expression
- Promotes collagen synthesis in cardiac fibroblasts
- Regulates cardiac fibrosis-related genes
- Useful in heart failure research
Medchemexpress LLC Anecortave acetate 5mg | 7753-60-8 | 386.48 g/mol | C23H30O5 | 5 MG
Anecortave acetate is an angiostatic research compound that inhibits pathological retinal neovascularization. Supplied as a high-purity solid for laboratory and preclinical studies, it is soluble in methanol and requires cold storage to maintain stability.
- High purity (99.81%).
- Solid form for handling and storage.
- Molecular formula C23H30O5 and molecular weight 386.48 g/mol.
- Soluble in methanol: 1 mg/mL; may require ultrasonic.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Available in small research sizes, including 5 mg.
Medchemexpress LLC Carperitide acetate | 1366000-58-9 | 99.8% | 3140.50 | 5 MG
Carperitide acetate is a 28-amino acid hormone, normally produced and secreted by the human heart in response to cardiac injury and mechanical stretch. It inhibits endothelin-1 secretion in a dose-dependent way. This product is for research use only and not sold to patients.
- 28-amino acid hormone
- Produced and secreted by the human heart
- Inhibits endothelin-1 secretion
- Purity of 99.8%
- Appears as a white to off-white solid
- Soluble in water (50 mg/mL in H2O)
Medchemexpress LLC Vitamin K1 | 84-80-0 | 98.6% | 450.70 | 500 MG
Vitamin K1 is a naturally occurring vitamin essential for blood coagulation and bone and vascular metabolism. It is a prenylated naphthoquinone synthesized by plants, green algae, and some cyanobacteria, acting as an electron carrier in photosystem I.
- Required for blood coagulation and bone and vascular metabolism in humans
- Shows significant antiproliferative effects and induces apoptosis in Caco-2, HT-29, and SW480 cell lines
- Increased dietary intake is associated with a reduced risk of incident diabetes
- Supplementation reverses high-fat diet-induced bone deterioration
- Topical application suppresses pigmentation and resolves bruising, promoting wound repair
Sigma Aldrich Fine Chemicals Biosciences Casein vitamin tested powd5KG
Casein is produced from skim milk. It is roughly made of 80% bovine milk protein and has only 10 to 20% essential amino acids per gram of protein.
