Formic Acid
Formic acid (HCOOH) is naturally-occurring, flammable, corrosive, organic, and the simplest carboxylic acid. Used as a hydride ion source in synthetic organic chemistry, a mobile phase component in HPLC, a preservative/antibacterial agent in agriculture, etc.
Formic or methanoic acid (CAS: 64-18-6; PubChem ID: 284) is a colorless organic acid with the formula HCOOH. At ambient temperatures, it has a strong, penetrating odor, like acetic acid. Used in chemical synthesis as an intermediate, this simple carboxylic acid is miscible in water and most organic solvents and is somewhat hydrocarbon-soluble.
Formic acid occurs naturally in the venom of some ants and bees. Formate, the conjugate base of formic acid, also occurs naturally in bodily fluids following methanol poisoning.
Formic acid is a source of hydride ion in synthetic organic chemistry, as in the Eschweiler-Clarke and Leuckart-Wallach reactions. It is also a useful component of the mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) for peptides, proteins, and intact viruses.
Although formic acid is easily metabolized and eliminated, it can have toxic effects. Methanol metabolism produces formic acid and formaldehyde, which are responsible for the optic nerve damage that results from methanol poisoning. Chronic exposure in humans may cause kidney damage and skin allergies in some people.
In diluted forms, formic acid and formate esters are used as artificial flavorings and perfume additives. In higher concentrations, formic acid is flammable, and skin and eye contact with concentrated liquid or vapors is dangerous.
In agriculture, formic acid is used as a preservative and antibacterial agent and by beekeepers to kill mites. It is useful in leather tanning, textile dyeing and finishing, and in rubber production. Formic acid replaces mineral acids in limescale removers and other cleaning products.
Sigma Aldrich Fine Chemicals Biosciences Formic acid puriss., meets analytical specifications of DAC, FCC, 98.0-100% | 64-18-6 | MFCD00003297 | 2.5L
Formic acid puriss., meets analytical specifications of DAC, FCC, 98.0-100% | Purity: 98.0-100% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 2.5L
Sigma Aldrich Fine Chemicals Biosciences Formic acid >=95%, FCC, FG | 64-18-6 | MFCD00003297 | 25KG
Formic acid >=95%, FCC, FG | Purity: >=95% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 25KG
Sigma Aldrich Fine Chemicals Biosciences Formic acid reagent grade, >=95% | 64-18-6 | MFCD00003297 | 4X100ML
Formic acid reagent grade, >=95% | Purity: >=95% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 4X100ML
Sigma Aldrich Fine Chemicals Biosciences Formic acid >=95%, FCC, FG | 64-18-6 | MFCD00003297 | 5KG
Formic acid >=95%, FCC, FG | Purity: >=95% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 5KG
Medchemexpress LLC SJ1008030 formic | 97.7% | 919.96 | 1 MG
SJ1008030 formic is a JAK2 PROTAC that selectively degrades JAK2. This compound inhibits MHH-CALL-4 cell growth with an IC50 of 5.4 nM and is suitable for leukemia research.
- Selectively degrades JAK2
- Inhibits MHH-CALL-4 cell growth with an IC50 of 5.4 nM
- Can be used for leukemia research
- Purity of 97.7%
- Supplied as a light yellow to yellow solid
- Molecular formula C43H45N13O9S
Medchemexpress LLC PKCiota-IN-2 formic | 99.0% | 402.36 | 100 MG
PKCiota-IN-2 formic is a potent inhibitor of PKCiota (PKC-ι) with an IC50 of 2.8 nM. It also demonstrates inhibitory activity against PKC-α and PKC-ε.
- Potent PKCiota (PKC-ι) inhibitor.
- Inhibits PKC-α and PKC-ε.
- Available in solid and solution forms.
- Purity: 99.04%.
- For research use only.
Sigma Aldrich Fine Chemicals Biosciences Formic acid | 64-18-6 | MFCD00003297 | 500 mL
Formic acid | Purity: 96% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 500 mL
Medchemexpress LLC SLB1122168 formic | C23H37N3O3 | 100 MG
SLB1122168 formic is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM. It is intended for research use only and not for patient administration.
- Potent Spns2-mediated S1P release inhibitor
- Inhibitor with an IC50 of 94 nM
- Intended for research use
Sigma Aldrich Fine Chemicals Biosciences Formic acid ACS reagent, 88-91, 64-18-6, MFCD00003297
Formic acid ACS reagent, 88-91
Medchemexpress LLC SLB1122168 formic | 2999629-17-1 | C23H37N3O3 | 50 MG
SLB1122168 formic is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM. It leads to a dose-dependent decrease in circulating lymphocytes, and in rats, it achieves a maximum concentration of 4 μM at 2 hours post-dose, maintaining levels ≥1 μM for 24 hours with a half-life of 8 hours.
- Potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM
- Induces a dose-dependent decrease in circulating lymphocytes
- Relevant for research in respiratory disease, inflammation or immune system disease, pulmonary disease, and lung fibrosis
- Acts on inflammation/immunology signaling pathways, GPCR/G protein, and LPL receptor
eMolecules 64-18-6 | Formic Acid, ACS Grade | Oakwood Chemicals | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 25g | 480143861
Formic Acid, ACS Grade | Oakwood Chemicals | 64-18-6 | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 25g | 480143861