NVR 3-778 is a first-in-class, orally bioavailable hepatitis B virus (HBV) capsid assembly modulator (CAM) of the sulfamoylbenzamide chemical class. It inhibits capsid assembly and has shown antiviral activity in cellular and preclinical models, reducing HBV DNA, HBsAg, and HBeAg levels; intended for research use in HBV mechanism and antiviral studies.
- Orally bioavailable small-molecule capsid assembly modulator.
- Demonstrated antiviral activity against multiple HBV genotypes in cellular models.
- Reduces HBV DNA, HBsAg, and HBeAg in preclinical studies.
- Suitable for in vitro and preclinical HBV research.
- Provided as a solid with high reported purity.
- Molecular identity and characterization data available for analytical verification.