Trifluoroacetic Acid
Trifluoroacetic acid is a corrosive organofluorine compound that is structurally analogous to, but stronger than, acetic acid. Available in various quantities and reagent grades, it is used in NMR spectroscopy, mass spectrometry, organic synthesis, etc.
Almost 100,000-fold more acidic than acetic acid, TFA is widely used in organic chemistry. TFA is used as a reagent in organic synthesis because of its properties: volatility, organic solvent solubility, and acidic strength. It is less oxidizing than sulfuric acid and is more readily available in its anhydrous form than some other acids . Other features include:
- Used in acid-catalyzed reactions, especially peptide synthesis (to cleave esters)
- Dissolves protein when mixed with liquid SO2
- Removes t-butyl derived side-chain protecting groups in Fmoc peptide synthesis
- Can remove the t-butoxycarbonyl protecting group in organic synthesis
- At low concentrations, acts as an ion-pairing agent for peptides and small proteins in organic compound liquid chromatography
- For acid-stable materials, can be a solvent for NMR spectroscopy
- Acts as a calibrant in mass spectrometry
- Used to produce trifluoroacetate salts
- An ingredient in adhesives, sealants, paints, and coatings
When TFA combines with bases and metals, especially light metals, a strong exothermic reaction occurs. When mixed with lithium aluminum hydride (LAH), the reaction is explosive.
Although nonflammable, TFA is corrosive to skin, eyes, and mucous membranes and requires careful use and handling. It is harmful when inhaled, causes severe skin burns and eye damage, and is toxic to aquatic organisms at even low concentrations.
TFA is also a product of the metabolic breakdown of the anesthetic agent halothane. It is the suspected cause of halothane-induced hepatitis.
Hampton Research 30% W/V POLYETHYLENE GL 200ML
HR2-609/30% w/v Polyethylene glycol 20,000 - 200 ml. Please note items from this supplier are non-returnable.
Sigma Aldrich Fine Chemicals Biosciences Trifluoroacetic acid suitable for HPLC, >=99.0% | 76-05-1 | MFCD00004169 | 4X100ML
Trifluoroacetic acid suitable for HPLC, >=99.0% | Purity: >=99.0% | Mol Wt: 114.02 | 76-05-1 | MFCD00004169 | 4X100ML
Sigma Organic Chemistry N-Boc-N'-TFA-pyrazole-1-carboxamidine | 1G
N-Boc-N'-TFA-pyrazole-1-carboxamidine, 1G
About This Item:
UNSPSC Code: 12352200
Storage: -20C
Chem-Impex International, Inc. Trifluoroacetic acid | 76-05-1 | MFCD00004169 | 100G
Trifluoroacetic acid, 76-05-1, MFCD00004169, 100G
Apexbio Technology LLC 5-hme-CTP 10x100ul (100 mM)
5-hme-CTP (5-hydroxymethylcytidine triphosphate) is a modified cytidine triphosphate bearing a hydroxymethyl group at the 5-position carbon This modification can enhance RNA stability and functionality During in vitro mRNA synthesis 5-hme-CTP can be incorporated into RNA molecules producing RNA containing 5-hydroxymethylcytidine Hydroxymethyl-modified RNA plays an essential role in studying RNA structure function and RNA-protein interactions Additionally 5-hme-CTP significantly improves RNA stability by reducing its intracellular degradation Thus this modified nucleotide has broad applications in gene expression research RNA-based drug development and gene therapy
Apexbio Technology LLC 2X hyperfusion plus master mix (With dye) 10X1ml
Our 2X Hyperfusion Plus Master Mix (With dye) product offers high fidelity strong amplification performance and faster extension speed simultaneously making it suitable for most PCR applications Hyperfusion Plus DNA Polymerase is created by fusing a Pyrococcus-like proofreading polymerase with a DNA binding domain providing increased fidelity and speed Hyperfusion Plus DNA Polymerase owns high fidelity 50 times lower error rate than Taq DNA Polymerase and 6 times lower error compared to Pyrococcus Furious DNA Polymerase Experimental results demonstrate that our Hyperfusion Plus polymerase can amplify genome fragments as long as 20 1 kb 2X Hyperfusion plus master mix (With dye) is a ready-to-use 2 premix solution containing polymerase dNTPs an already optimized buffer system and dye Our mix is ideal for any detection and the PCR product can be directly electrophoresed after the amplification without the need to add a loading buffer
Selleck Chemical LLC Z-LEHD-FMK TFA
Z-LEHD-FMK TFA (Caspase-9 Inhibitor) is a cell-permeable competitive and irreversible inhibitor of enzyme caspase-9 which helps in cell survival
Selleck Chemical LLC Z-LEHD-FMK TFA
Z-LEHD-FMK TFA (Caspase-9 Inhibitor) is a cell-permeable competitive and irreversible inhibitor of enzyme caspase-9 which helps in cell survival
Sigma Aldrich Fine Chemicals Biosciences Trifluoroacetic anhydride ReagentPlus(R), >=99% | 407-25-0 | MFCD00000416 | 3KG
Trifluoroacetic anhydride ReagentPlus(R), >=99% | Purity: >=99% | Mol Wt: 210.03 | 407-25-0 | MFCD00000416 | 3KG
Sigma Aldrich Fine Chemicals Biosciences Trifluoroacetic acid 99 fo25G
TRIFLUOROACETIC Trifluoroacetic acid 99 fo25G
Sigma Aldrich Fine Chemicals Biosciences Trifluoroacetic acid Reage
TRIFLUOROACETIC Trifluoroacetic acid Reage
TARGETMOL CHEMICALS INC Dermorphin TFA 2MG
Also available in 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Dermorphin TFA is a new class of opioids-like peptides Purity 100%