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Filtered Search Results
Medchemexpress LLC N6-benzoyl-2'-deoxyadenosine monohydrate | 305808-19-9 | MFCD00009628 | ≥98.0% | 373.37 g/mol | C17H19N5O5 | 1 G
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N6-Benzoyl-2'-deoxyadenosine monohydrate is a purine nucleoside analog provided as a monohydrate solid for research and diagnostic applications. It is used to study DNA duplex interactions and related biochemical assays, and is supplied at research-grade purity for laboratory use.
- High purity (≥98.0%).
- Monohydrate solid form suitable for laboratory assays.
- Used as a nucleoside analog to probe DNA duplex structure in assays.
- CAS number 305808-19-9.
- Molecular weight 373.37 g/mol.
- Available in a 1 g pack and larger sizes.
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TARGETMOL CHEMICALS INC DEMECARIUM BROMIDE 50MG
Also available in 2 mg 5 mg 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Demecarium bromide (BC-48) is a potent cholinesterase inhibitorand is treatment glaucoma agent. purity: 98%
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Medchemexpress LLC N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine | 67219-55-0 | 98.9% | 633.69 | 25 G
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N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is a compound designed for the synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. It serves as a valuable tool for investigating enzyme-catalyzed cleavage processes in DNA.
- Used for synthesis of oligodeoxynucleotides
- Contains a 3'-S-phosphorothiolate (3'-PS) linkage
- Useful tool for probing enzyme-catalyzed cleavage processes in DNA
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Medchemexpress LLC Otilonium (bromide) | 26095-59-0 | 99.7% | 1 ML
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Otilonium bromide is an orally active mAChR inhibitor and smooth muscle relaxant. It can interfere with the mobilization of calcium in intestinal smooth muscle and is used for research on irritable bowel syndrome.
- Inhibits acetylcholine-induced human colonic crypt calcium signals in a dose-dependent manner with an IC50 of 880 nM.
- Inhibits Ca2+ uptake in bovine chromaffin cells at 30 μM.
- Targets mAChR and is involved in GPCR/G Protein and Neuronal Signaling pathways.
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Medchemexpress LLC Cyanine 3.5 bromide | 98.6% | 734.72 g·mol⁻1 | C42H44BrN3O4 | 10 MG
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Cyanine 3.5 bromide is a red reactive fluorescent dye used for covalent labeling of primary amines on peptides, proteins, and oligonucleotides for fluorescence imaging and detection. It exhibits red fluorescence with excitation near 591 nm and emission near 604 nm, and is typically supplied as a small research-scale powdered quantity.
- Reactive NHS ester for covalent labeling of primary amines.
- Red fluorescence with typical excitation ~591 nm and emission ~604 nm.
- Molecular formula C42H44BrN3O4, molecular weight 734.72 g·mol-1.
- Purity reported around 98.6%.
- Supplied as a 10 mg powder; store at -20 °C and protect from light.
- Suitable for labeling peptides, proteins, and oligonucleotides in imaging applications.
- Stable in common organic solvents; handle with appropriate safety precautions.
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Apexbio Technology LLC Otilonium Bromide 26095-59-0 10mM (in 1mL DMSO)
Otilonium Bromide (CAS 26095-59-0) is an orally-administered muscarinic acetylcholine receptor (mAChR) antagonist exhibiting smooth muscle relaxation properties Its mechanism involves inhibition of calcium mobilization within intestinal smooth muscle cells lowering intracellular free calcium levels and thus attenuating muscle contractile activity In research settings Otilonium Bromide is commonly employed to investigate pathophysiological processes in irritable bowel syndrome (IBS) and dysfunctions associated with intestinal smooth muscle motility
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Apexbio Technology LLC Tiotropium Bromide 136310-93-5 10mM (in 1mL DMSO)
Tiotropium Bromide (CAS 136310-93-5) is a potent antagonist of muscarinic acetylcholine receptors (mAChRs) By competitively inhibiting acetylcholine binding at these receptors it prevents receptor activation and subsequent signaling cascades leading to decreased neuronal transmission and smooth muscle relaxation As a long-acting anticholinergic bronchodilator with activity lasting approximately 24 hours Tiotropium Bromide is widely studied in managing chronic obstructive pulmonary disease (COPD) including cases complicated by chronic heart failure
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Medchemexpress LLC Umeclidinium (bromide) | 869113-09-7 | 508.49 | 5 G
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Umeclidinium bromide is a novel muscarinic acetylcholine receptor (mAChR) antagonist. It exhibits high affinity for human M1-M5 mAChRs, with Ki values ranging from 0.05 to 0.16 nM. This compound demonstrates antagonist activity at the human cloned muscarinic M3 receptor and inhibits the human ether-a-go-go-related gene (hERG) channel tail current.
- Targets mAChR1 and mAChR5.
- Inhibits acetylcholine-induced calcium mobilization in CHO cells.
- Demonstrates slow functional reversibility at M3 mAChRs.
- Inhibits human ether-a-go-go-related gene channel tail current.
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Medchemexpress LLC 1,3,5-Tri-O-benzoyl-a-D-ribofuranose | 22224-41-5 | 99.8% | 462.45 | 5 G
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1,3,5-Tri-O-benzoyl-a-D-ribofuranose is a purine nucleoside analog that exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms involve inhibiting DNA synthesis and inducing apoptosis, among other processes.
- Purine nucleoside analog
- Exhibits broad antitumor activity
- Targets indolent lymphoid malignancies
- Inhibits DNA synthesis
- Induces apoptosis
- Useful for cancer research
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Medchemexpress LLC N6-benzoyl-2'-deoxyadenosine monohydrate | 305808-19-9 | MFCD00149575 | >98.0% | 373.4 g/mol | C17H19N5O5 | 5 G
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N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analog of deoxyadenosine bearing an N6-benzoyl protecting group. It is provided as a monohydrate solid for research use (CAS 305808-19-9) with purity ≥98.0%, and is used as an intermediate in nucleoside chemistry, oligonucleotide synthesis, and studies of nucleoside analog activity.
- High purity suitable for research applications.
- Monohydrate solid form for stable handling and storage.
- Serves as an intermediate in nucleoside and oligonucleotide synthesis.
- Compatible with standard analytical and synthetic workflows.
- Supplied in small-scale laboratory pack sizes for bench use.
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eMolecules 1076199-21-7 | Ambeed | tert-Butyl (2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)ethyl)carbamate | 100mg | 552573626 | A138365 | MFCD09840081 | 356.257 | C13H26BrNO5
Ambeed | 2-Amino-3-bromobenzonitrile | 1g | 552746008 | A597346 | 114344-60-4 | MFCD05670539 | 197.035 | C7H5BrN2
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Apexbio Technology LLC Umeclidinium bromide 869113-09-7 5mg
Umeclidinium bromide (CAS 869113-09-7) is a potent and long-acting antagonist of muscarinic acetylcholine receptors (mAChRs) displaying high affinity for subtypes M1 M5 with Ki values of 0 16 nM 0 15 nM 0 06 nM 0 05 nM and 0 13 nM respectively It selectively targets mAChRs without observable activity at unrelated receptors or channels such as / opioid receptors sodium channels or dopamine transporters In cell-based assays using CHO cells expressing recombinant human mAChRs umeclidinium inhibits acetylcholine-induced calcium flux with pA2 values between 9 6 and 10 6 for M1 M3 receptors In murine models it reverses acetylcholine-driven bronchoconstriction Umeclidinium bromide is broadly applied in research focused on pulmonary disease mechanisms and drug development
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Medchemexpress LLC Sepantronium bromide | 781661-94-7 | MFCD11983133 | 98.9% | 443.3 g/mol | C20H19BrN4O3 | 100 MG
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Sepantronium bromide (YM-155) is a small-molecule survivin inhibitor used in research to suppress survivin expression and study apoptosis in cancer models. It shows potent activity in cellular assays and is supplied at high purity for biochemical and cell-based experiments.
- Potent survivin inhibition (IC50 ~0.54 nM).
- High purity: 98.9%.
- Available as a solid or as a 10 mM solution for flexible dosing.
- Chemical formula C20H19BrN4O3; mol wt 443.3 g/mol.
- Intended for research use only.
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eMolecules 7789-45-9 | Copper(II) bromide | Chem-Impex | MFCD00010970 | 223.354 | Br2Cu | 98.000 | [Cu++].[Br-].[Br-] | 1kg | 342449731
Copper(II) bromide | Chem-Impex | 7789-45-9 | MFCD00010970 | 223.354 | Br2Cu | 98.000 | [Cu++].[Br-].[Br-] | 1kg | 342449731
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Selleck Chemical LLC Sepantronium Bromide (YM155) S1130-10mM/1mL
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0 54 nM in HeLa-SURP-luc and CHO-SV40-luc cells does not significantly inhibit SV40 promoter activity but is observed to slightly inhibit the interaction of Survivin with XIAP YM155 down-regulates survivin and XIAP modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells Phase 2
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