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Filtered Search Results
Medchemexpress LLC Cefozopran hydrochloride | 113981-44-5 | 95.0% | 100 MG
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Cefozopran hydrochloride is a semi-synthetic, parenteral, fourth-generation cephalosporin. This antibiotic exhibits a broad spectrum of antibacterial activity, effectively inhibiting most gram-negative and gram-positive organisms.
- Exhibits broad-spectrum antibacterial activity.
- Effectively inhibits most gram-negative and gram-positive organisms.
- Shows good activity against methicillin-susceptible staphylococci, enterococci, and viridans group streptococci.
- Active against gram-negative organisms, including Haemophilus influenza.
- Demonstrates comparatively good activity against enterococci and P. aeruginosa.
- Effective against acute respiratory tract infections in mice models.
- Effective against chronic respiratory tract infection in mice models.
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Ambeed AMBEED
5000847973 5 7-DICHLORO-1 6-NAPHTH 5G
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Ambeed AMBEED
5000847976 5 7-DICHLORO-1 6-NAPHTH 100MG
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Medchemexpress LLC Epirubicin hydrochloride (standard) | 56390-09-1 | 99.91% | 579.98 | 100 MG
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Epirubicin hydrochloride (Standard) is an analytical standard and a semisynthetic L-arabino derivative of doxorubicin, primarily used in research and analytical applications. It functions as an antineoplastic agent by inhibiting Topoisomerase and also inhibits DNA and RNA synthesis. Additionally, it acts as a Forkhead box protein p3 (Foxp3) inhibitor, effectively inhibiting regulatory T cell activity.
- Analytical standard for research and analytical applications
- Semisynthetic L-arabino derivative of doxorubicin
- Acts as an antineoplastic agent
- Inhibits Topoisomerase, DNA, and RNA synthesis
- Functions as a Forkhead box protein p3 (Foxp3) inhibitor
- Inhibits regulatory T cell activity
- Used as a reference standard in qualitative, quantitative, and methodological research experiments (e.g., HPLC, GC, MS)
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Medchemexpress LLC Ilginatinib hydrochloride (NS-018 hydrochloride) | 1239358-85-0 | 98.9% | 425.89 | 1 ML
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Ilginatinib hydrochloride (NS-018 hydrochloride) is a highly active and orally bioavailable JAK2 inhibitor. It demonstrates significant selectivity for JAK2 over other JAK family members and inhibits Src-family kinases. This compound exhibits potent inhibitory activity against cell lines with specific JAK2 mutations, showing minimal cytotoxicity to other hematopoietic cell lines.
- Highly active and orally bioavailable JAK2 inhibitor
- Shows selectivity for JAK2 over JAK1, JAK3, and Tyk2
- Inhibits Src-family kinases (SRC and FYN)
- Weakly inhibits ABL and FLT3
- Potent inhibitory activity against cell lines with JAK2V617F or MPLW515L mutations
- Minimal cytotoxicity against hematopoietic cell lines lacking constitutively activated JAK2
- For research use only
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TARGETMOL CHEMICALS INC BI-4020 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BI-4020 is a fourth-generation orally active and non-covalent inhibitor of EGFR tyrosine kinase. BI-4020 exhibits activity agains the triple mutant EGFR del19 T790M C797S variant (IC50=0.2 nM in BaF3 cell lines) the double mutant EGFR del19 T790M and primary mutant EGFR del19 (IC50=1 nM) and EGFR wt (IC50=190 nM). BI-4020 exhibits high kinome selectivity and good DMPK properties. purity: 98%
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Medchemexpress LLC Siramesine hydrochloride | 224177-60-0 | 99.7% | C30H32ClFN2O | 2 MG
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Siramesine hydrochloride, also known as Lu 28-179 hydrochloride, is a potent sigma-2 receptor agonist. It demonstrates high selectivity for sigma-2 receptors over sigma-1 receptors. This compound triggers cell death by destabilizing mitochondria and exhibits anti-cancer activity.
- Potent sigma-2 receptor agonist
- High selectivity for sigma-2 receptors
- Triggers cell death via mitochondrial destabilization
- Shows anti-cancer activity
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Medchemexpress LLC Tetracaine hydrochloride | 136-47-0 | 99.91% | 1 G
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Tetracaine hydrochloride (Amethocaine hydrochloride) is a calcium channel protein inhibitor that blocks voltage-sensitive release of Ca2+ from the sarcoplasmic reticulum. It is primarily used topically in ophthalmology and as an antipruritic. It also alters the function of calcium release channels (ryanodine receptors) that regulate calcium release from intracellular stores.
- Blocks voltage-sensitive release of Ca2+ from the sarcoplasmic reticulum.
- Used topically in ophthalmology.
- Acts as an antipruritic.
- Alters the function of calcium release channels (ryanodine receptors).
- Inhibits spontaneous calcium release events at low concentrations.
- Completely blocks calcium release at high concentrations.
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Medchemexpress LLC Amantadine hydrochloride | 665-66-7 | 98.0% | 5 G
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Amantadine hydrochloride is an orally active and potent antiviral agent, effective against influenza A viruses. It inhibits various ion channels, including NMDA, M2, and Coronavirus ion channels. The compound also demonstrates anti-orthopoxvirus and anticancer activities, and is utilized in research for Parkinson's disease, postoperative cognitive dysfunction (POCD), and COVID-19.
- Potent antiviral agent, effective against influenza A viruses and SARS-CoV-2 replication
- Inhibits various ion channels, including NMDA, M2, and Coronavirus
- Exhibits anti-orthopoxvirus and anticancer activities
- Used in research for Parkinson's disease, postoperative cognitive dysfunction, and COVID-19
- Induces apoptosis and arrests cell cycle in cancer cells
- Inhibits surgery-induced neuroinflammation and learning/memory impairment
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Medchemexpress LLC Lofexidine hydrochloride | 21498-08-8 | 99.7% | 1 ML
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Lofexidine hydrochloride is a selective α2-receptor agonist, commonly used in research to alleviate the physical symptoms of opioid withdrawal. It is intended for research use only.
- Selective α2-receptor agonist
- Alleviates physical symptoms of opioid withdrawal
- For research use only
- Stable under recommended storage conditions
- Solid appearance
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Sigma Aldrich Fine Chemicals Biosciences 7-Bromo-3-hydroxy-2-naphthoic acid >=98.0% (HPLC), 98.0-102.0 wt. % (AT) | 1779-11-9 | MFCD00137823 | 5G
7-Bromo-3-hydroxy-2-naphthoic acid >=98.0% (HPLC), 98.0-102.0 wt. % (AT) | Purity: >=98.0% (HPLC); 98.0-102.0 wt. % (AT) | Mol Wt: 267.08 | 1779-11-9 | MFCD00137823 | 5G
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TARGETMOL CHEMICALS INC BI-3406 5MG
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. BI-3406 is an orally active highly potent and selective between KRAS and Son of Sevenless 1 (SOS1) interaction inhibitor(IC50 6 nM)with anticancer activity. purity: 99%
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000771656 NAPHTHALENE-2 7-DICA 250MG
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AdipoGen trans-Diphenyl-2-propen-1-ol
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Chemical. CAS 62668-02-4. Formula C15H14O. MW 210.27. Synthetic. Building block for synthesis.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000696054 2-METHYL-1-NAPHTHOL 100MG
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