Naphthalenes

Apexbio Technology LLC 6-Methoxy-2-naphthoic-acid

6-Methoxy-2-naphthoic acid (CAS No 2471-70-7) is a compound of interest in biomedical research originating from the naphthalene family known for its role in investigating cellular signaling pathways Its mechanism of action typically involves modulating specific enzymes and pathways related to inflammation and cellular proliferation The compound demonstrates in vitro activity often in the nanomolar to low micromolar range making it a candidate for studies requiring high precision It is frequently utilized in various cell models to explore biological responses and experimental pathways and it aids in animal studies aimed at understanding systemic effects Drug screening processes incorporate this compound to assess potential therapeutic benefits and mechanistic insights Experimental concentrations typically depend on the specific research design allowing flexibility in application according to study objectives

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Medchemexpress LLC Stachydrine hydrochloride | 4136-37-2 | MFCD00060174 | 179.64 | 1 ML

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Stachydrine hydrochloride, a major active constituent of Leonurus artemisia, is a potential therapy for cardiovascular diseases. It inhibits the NF-κB signal pathway and demonstrates anti-hypertrophic activities. Research indicates it can suppress p-IκB (ser32) protein and NF-κB (p65) protein, and inhibit MCF-7 and T47D cell proliferation.

• Inhibits NF-κB signal pathway
• Exhibits anti-hypertrophic activities
• Suppresses p-IκB (ser32) protein in cytosol
• Suppresses NF-κB (p65) protein in nucleus
• Inhibits MCF-7 and T47D cell proliferation
• Induces G1 phase cell cycle arrest in cell lines

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Medchemexpress LLC G4RGDSP, integrin-binding peptide | 774577-43-4 | 99.6% | 758.74 | 50 MG

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G4RGDSP, integrin-binding peptide, is a cell integrin-binding peptide that specifically targets integrin receptors. It is designed to be coupled with alginate to enhance the viability of cells within a scaffold. This peptide can also be utilized as an extrudable carrier for chondrocyte delivery, facilitating studies involving 3D printing technology.

• Targets integrin receptors as a cell integrin-binding peptide.
• Can be coupled to alginate to increase cell viability in scaffolds.
• Applicable as an extrudable carrier for chondrocyte delivery in 3D printing technology research.
• Increases the expression of aggregin, collagen type II, and sox9 genes in HAC cells in vitro.

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Medchemexpress LLC G4RGDSP, integrin-binding peptide | 774577-43-4 | 99.6% | 758.74 | 10 MG

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G4RGDSP, integrin-binding peptide, is a cell integrin-binding peptide that targets integrin receptors. It can be coupled to alginate to increase the viability of cells in the scaffold. It is also used as an extrudable carrier for chondrocyte delivery for the study of 3D printing technology.

• Targets integrin receptors
• Can be coupled to alginate to increase cell viability in scaffolds
• Used as an extrudable carrier for chondrocyte delivery for 3D printing technology studies
• Increases expression of aggregin, collagen type II, and sox9 genes in HAC cells

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Medchemexpress LLC Higenamine hydrochloride | 11041-94-4 | 307.77 | 500 MG

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Higenamine hydrochloride is a selective inhibitor of LSD1 with an IC50 of 1.47 μM, naturally sourced from aconite. It exhibits anti-inflammatory and antibacterial properties and can mitigate IL-1β-induced apoptosis via the ROS-mediated PI3K/Akt signaling pathway. Additionally, it offers protective effects for brain cells against oxygen deprivation and stimulates bone formation in osteoporosis through the SMAD2/3 pathway. It is utilized in research for various conditions, including cancer, inflammation, and cardiorenal syndrome.

• Selective LSD1 inhibitor (IC50=1.47 μM)
• Derived from aconite
• Possesses anti-inflammatory activity
• Exhibits antibacterial activity
• Attenuates IL-1β-induced apoptosis
• Protects brain cells from oxygen deprivation
• Promotes bone formation in osteoporosis
• Relevant for studying cancer, inflammation, and cardiorenal syndrome

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Medchemexpress LLC BI-27 SUPPLEMENT 50 10ML

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BI-27 SUPPLEMENT 50 10ML