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Filtered Search Results
Medchemexpress LLC Gabapentin hydrochloride | 60142-95-2 | 98.0% | C9H18ClNO2 | 500 MG
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Gabapentin hydrochloride is a potent, orally active P/Q type Ca2+ channel blocker. It inhibits neuronal Ca2+ influx and reduces neurotransmitter release. It is also a GABA analog that can be used to relieve neuropathic pain.
- Potent and orally active P/Q type Ca2+ channel blocker
- Inhibits neuronal Ca2+ influx
- Reduces neurotransmitter release
- GABA analog for relieving neuropathic pain
- For research use only
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Cayman Chemical 10-hydroxy Decanoic Acid, Purity: ≥98%, CAS: 1679-53-4, 5 g
A hydroxy fatty acid and a major component of worker bee mandibular blend pheromones; reduces LPS-induced nitric oxide production in RAW 264.7 cells at 5 mM
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Medchemexpress LLC 8-AMINO-2-NAPHTHOL 10G
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8-AMINO-2-NAPHTHOL 10G
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Medchemexpress LLC Aceclidine hydrochloride (quinuclidin-3-yl acetate hydrochloride) | 6109-70-2 | 98.0% | 205.68 | 100 MG
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Aceclidine hydrochloride is a modulator of M3 muscarinic acetylcholine receptor and a M1 receptor agonist (EC50: 40 μM). It acts as a cycloplegic agent, surfactant, tonicity adjustor, viscosity enhancer, and antioxidant. It has potential for research into refractive errors of the eye, xerostomia, Sjogren's syndrome, glaucoma, conjunctivitis, lacrimal gland disease, and esotropia.
- Modulator of muscarinic acetylcholine receptor.
- Agonist of muscarinic acetylcholine receptor.
- Cycloplegic agent.
- Surfactant.
- Tonicity adjustor.
- Viscosity enhancer.
- Antioxidant.
- Potential for research of refractive errors of the eye.
- Potential for research of xerostomia.
- Potential for research of Sjogren's syndrome.
- Potential for research of glaucoma.
- Potential for research of conjunctivitis.
- Potential for research of lacrimal gland disease.
- Potential for research of esotropia.
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Medchemexpress LLC 4-Hydroxy-2-naphthoic acid | 1573-91-7 | 99.67% | 188.18 | 500 MG
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4-Hydroxy-2-naphthoic acid is a drug intermediate used for the synthesis of various active compounds. It is intended for research use only.
- High purity: The product boasts a purity of 99.67%.
- Drug intermediate: Serves as a key intermediate in the synthesis of diverse active compounds.
- Research use: Specifically designated for research purposes.
- Availability: Offered in various quantities for purchase.
- Comprehensive documentation: Supplied with a data sheet, certificate of analysis (COA), safety data sheet (SDS), and handling instructions.
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Medchemexpress LLC Adriforant hydrochloride (PF-3893787 hydrochloride) | 2096455-90-0 | 98.0% | 371.74 | 1 ML
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Adriforant hydrochloride (PF-3893787 hydrochloride) is a novel histamine H4 receptor antagonist with a binding affinity (Ki) of 2.4 nM and is also a functional (Ki) antagonist at 1.56 nM. It is suitable for laboratory research and studies involving histamine receptors.
- Novel histamine H4 receptor antagonist
- High binding affinity and functional antagonism
- Suitable for high-speed applications
- Leak-resistant cap for secure storage
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eMolecules 1141-38-4 | Naphthalene-2,6-dicarboxylic acid | Apollo Scientific | MFCD00004105 | 216.192 | C12H8O4 | 98.000 | OC(=O)c1ccc2cc(ccc2c1)C(O)=O | 25g | 562433776
Naphthalene-2,6-dicarboxylic acid | Apollo Scientific | 1141-38-4 | MFCD00004105 | 216.192 | C12H8O4 | 98.000 | OC(=O)c1ccc2cc(ccc2c1)C(O)=O | 25g | 562433776
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Medchemexpress LLC Trilaciclib hydrochloride | 1977495-97-8 | 99.7% | 519.47 g/mol | C24H32Cl2N8O | 1 MG
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Trilaciclib hydrochloride is the hydrochloride salt of trilaciclib, an orally active CDK4/6 inhibitor supplied as a research-grade analytical standard. It is provided as a light yellow to yellow solid for biochemical, cell-based, and preclinical studies, with documented activity against CDK4 and CDK6 and batch-specific characterization available.
- Orally active CDK4/6 inhibitor for cell-cycle arrest studies.
- High purity suitable for analytical and preclinical research.
- Documented potency: CDK4 IC50 ≈ 1 nM; CDK6 IC50 ≈ 4 nM.
- Solid formulation for ease of handling and storage.
- Batch-specific datasheet and COA available for quality verification.
- Intended for research use only; not for human or clinical use.
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Medchemexpress LLC Revaprazan (hydrochloride) | 178307-42-1 | 1 ML
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Revaprazan hydrochloride is a reversible proton pump inhibitor. It inhibits gastric acid secretion and protects gastric mucosa. It can also inhibit IkappaB-alpha degradation and Akt inactivation, leading to the attenuation of H. pylori-induced COX-2 expression. This product is used for research on infections and inflammation, such as H. pylori-infected gastric inflammation and gastric ulcers.
- Reversible proton pump inhibitor
- Inhibits gastric acid secretion
- Protects gastric mucosa
- Attenuates H. pylori-induced COX-2 expression
- Reduces H. pylori-stimulated COX-2 expression and activity in AGS cells
- Inhibits transcription activity of NF-κB in H. pylori-stimulated AGS cells
- Improves retarded cell growth in H. pylori-stimulated AGS cells
- Used for research on infection and inflammation
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Medchemexpress LLC BI-27 SUPPLEMENT 50 50ML
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BI-27 SUPPLEMENT 50 50ML
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Medchemexpress LLC Amantadine hydrochloride | 665-66-7 | 98.0% | 10 G
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Amantadine hydrochloride is an orally active and potent antiviral agent effective against influenza A viruses. It inhibits various ion channels, including NMDA and M2, and also targets Coronavirus ion channels. This compound also demonstrates anti-orthopoxvirus and anticancer activities, making it suitable for research in Parkinson's disease, postoperative cognitive dysfunction (POCD), and COVID-19.
- Inhibits SARS-CoV-2 replication
- Inhibits proliferation of HepG2 and SMMC-7721 cells
- Arrests cell cycle at G0/G1 phase and induces apoptosis
- Reduces levels of cell cycle-related genes and proteins
- Reduces Bcl-2 and increases Bax protein and mRNA levels
- Inhibits surgery-induced neuroinflammation and learning and memory impairment
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Medchemexpress LLC PRMT5-IN-1 hydrochloride | 99.5% | 455.29 | 1 MG
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PRMT5 IN-1 hydrochloride (compound 9) is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor. It functions as a hemiaminal and can be converted to aldehydes, reacting with C449 to form covalent adducts under physiological conditions. This compound inhibits cellular sDMA expression and cell proliferation in Granta-519 cells.
- Potent, selective PRMT5 inhibitor
- IC50 of 11 nM for PRMT5/MEP50
- Inhibits cellular sDMA expression with an IC50 of 0.012 μM
- Inhibits cell proliferation in Granta-519 cells with an IC50 of 0.06 μM
- Forms covalent adducts with C449
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Medchemexpress LLC RIBOCICLIB HYDROCHL 25 mg
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RIBOCICLIB HYDROCHL 25MG
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Medchemexpress LLC DELTARASIN HYDROCHL 100 mg
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DELTARASIN HYDROCHL 100MG
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Medchemexpress LLC DOBUTAMINE HYDROCHL 25 mg
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DOBUTAMINE HYDROCHL 25MG
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