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Polycyclic aromatic hydrocarbon compounds that consist of ten carbon atoms and eight hydrogen atoms fused into two benzene rings; it is the simplest polycyclic aromatic hydrocarbon.
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2-(Naphthalen-2-yl)acetonitrile is an organic intermediate used in medicinal chemistry for the synthesis of various active compounds. It is supplied as a white to off-white solid (C12H9N, molecular weight 167.21) for research applications and is provided with high reported purity.
Used as a drug intermediate for synthesis of active compounds.
High reported purity suitable for research applications.
White to off-white solid physical form.
Molecular formula C12H9N and molecular weight 167.21.
Available in multiple pack sizes for laboratory use.
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2-(Naphthalen-2-yl)acetonitrile (CAS 7498-57-9) is an organic intermediate used in pharmaceutical and chemical research to build more complex molecules. It is a small, nitrile-bearing aromatic compound with formula C12H9N and molecular weight 167.21 g/mol, supplied for laboratory research use only.
Used as a building block for synthesis of active compounds.
Molecular formula C12H9N.
Molecular weight 167.21 g/mol.
Provided as a solid reagent suitable for organic synthesis.
Intended for research use only; not for human or clinical use.
Available in laboratory pack sizes including 25 g.
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2-(Naphthalen-2-yl)acetonitrile is a small-molecule intermediate used primarily in medicinal chemistry and organic synthesis. It serves as a building block for preparing more complex target molecules in research and development and is supplied with characterization and storage guidance for laboratory use.
Solid, white to off-white appearance.
High purity suitable for synthetic workflows.
Molecular formula C12H9N; molecular weight 167.21 g·mol⁻¹.
CAS number 7498-57-9 for unambiguous identification.
Intended for use as a chemical intermediate in research and development.
Store at room temperature; in solution, keep at -20°C to -80°C as recommended.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2-(Naphthalen-2-yl)acetonitrile is an organic intermediate used in medicinal chemistry for the synthesis of various active compounds. It is provided for research use only and is not intended for human therapeutic use.
used as a drug intermediate in organic synthesis.
high purity suitable for research (reported 99.96%).
chemical formula C12H9N and molecular weight 167.21 g·mol⁻¹.
available in laboratory-scale pack sizes, including 10 g.
supplied with safety and datasheet documentation for handling.
stable solid; store in a cool, dry place as indicated in the SDS.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2-(Naphthalen-2-yl)acetonitrile is a chemical intermediate used in organic synthesis and medicinal chemistry research to prepare substituted naphthyl derivatives and related compounds. It is supplied as a solid with high reported purity and is accompanied by analytical and safety documentation for laboratory use.
High purity: 99.96%.
Molecular formula C12H9N and molecular weight 167.21 g/mol.
Solid, white to off-white appearance for straightforward handling.
Offered in multiple laboratory-scale pack sizes including 100 g.
Provided with downloadable COA, data sheet, and SDS documentation.
Suitable as an intermediate for medicinal chemistry and organic synthesis.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
2-(Naphthalen-2-yl)acetonitrile is a chemical intermediate used in the synthesis of active pharmaceutical compounds and research-stage derivatives. It has molecular formula C12H9N and a molecular weight of 167.21 g/mol. The product is supplied in laboratory and bulk pack sizes and is accompanied by a product datasheet and safety data sheet for research use only.
Drug intermediate for synthesis of active pharmaceutical compounds.
Molecular formula C12H9N; molecular weight 167.21 g/mol.
High reported purity (99.96%).
Available in laboratory and bulk pack sizes, including 500 g.
Supplied with accompanying datasheet and safety data sheet.
Intended for research use; not for human or veterinary use.
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Adapalene (CD271) is a third-generation synthetic retinoid primarily used for acne research. It acts as a potent RAR agonist and non-competitively inhibits the enzymatic activity of GOT1, also exhibiting anti-tumor activity. It is supplied as a 10 mM solution in DMSO, ready for reconstitution.
Potent RAR agonist
Inhibits GOT1 enzymatic activity
Exhibits anti-tumor activity
Supplied as a 10 mM solution in DMSO
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Adapalene is a third-generation synthetic retinoid widely used for acne research. It acts as a potent RAR agonist, with AC50s of 2.3 nM for RARβ, 9.3 nM for RARγ, and 22 nM for RARα. This compound also non-competitively inhibits the enzymatic activity of GOT1 and exhibits anti-tumor activity.
Third-generation synthetic retinoid
Potent RAR agonist for RARβ, RARγ, and RARα
Non-competitive inhibitor of GOT1 enzymatic activity
Exhibits anti-tumor activity
Induces apoptosis and inhibits proliferation in ES-2 cells
Inhibits growth of DLD1 cell-derived xenograft tumors
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Adapalene (CD271) is a third-generation synthetic retinoid primarily used for acne research. It functions as a potent RAR agonist and non-competitively inhibits GOT1 enzymatic activity, also demonstrating anti-tumor properties.
Acts as a potent RAR agonist with varying AC50s for RAR subtypes.
Inhibits viability of various cancer cell lines.
Induces apoptosis and inhibits proliferation in ES-2 cells.
Increases G1-phase population in LoVo or DLD1 cells.
Inhibits GOT1 activity.
Inhibits expression of plasma membrane-associated enzyme transglutaminase Type I.
Inhibits growth of DLD1 cell-derived xenograft tumors in BALB/C nude mice, reducing tumor weight and volume.
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