Phenanthrenes and derivatives
Medchemexpress LLC Hypericin (Standard) | 548-04-9 | 504.44 | 50 MG
Hypericin (Standard) is the analytical standard of Hypericin, a naturally occurring substance found in *Hypericum perforatum L*. It acts as an inhibitor of various biological targets and exhibits antitumor, antiviral, and antidepressive activities. This analytical standard is intended for research and analytical applications.
- Used as a reference standard for assay
- Utilized in qualitative research experiments
- Utilized in quantitative research experiments
- Utilized in methodological research experiments involving HPLC, GC, and MS
Medchemexpress LLC Hypericin | 548-04-9 | MFCD00016683 | 98.2% | 504.44 | C30H16O8 | 10 MG
Hypericin is an analytical reference standard of a naturally occurring compound found in Hypericum perforatum. It is a brown to reddish-brown solid (C30H16O8; MW 504.44 g/mol) supplied at high purity for research and analytical applications, including qualitative and quantitative methods. Store and handle according to the Certificate of Analysis and applicable safety data.
- Analytical reference standard suitable for HPLC, GC, and MS
- High purity for reliable qualitative and quantitative analysis
- Brown to reddish brown solid form for ease of handling in small-batch assays
- Derived from plant source (Hypericum perforatum)
- Supplied in small sizes appropriate for analytical work
TARGETMOL CHEMICALS INC HYPERICIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Hypericin (Cyclosan) has antineoplastic activity. 2. Hypericin has antibiotic and antiviral activities. 3. Hypericin has antidepressive activity through inhibiting monoamine oxidase enzyme. 4. Hypericin inhibits RANKL-mediated osteoclastogenesis via affecting ERK signalling in vitro and suppresses wear particle-induced osteolysis in vivo. purity: 99%
Medchemexpress LLC AM095 free acid | 1228690-36-5 | 99.0% | 456.49 | 200 MG
AM095 free acid is a potent LPA1 receptor antagonist that effectively inhibits LPA-induced calcium flux in CHO cells transfected with human or mouse LPA1. It also significantly reduces LPA-induced vasorelaxation and inhibits LPA-driven chemotaxis in various cell types. In preclinical studies, it has shown to attenuate bleomycin-induced dermal fibrosis and decrease kidney fibrosis in a mouse model of unilateral ureteral obstruction. The compound exhibits high oral bioavailability, a moderate half-life, and is well tolerated in animal models.
- Potent LPA1 receptor antagonist.
- Inhibits LPA-induced calcium flux in CHO cells.
- Reduces LPA-induced vasorelaxation.
- Inhibits LPA-driven chemotaxis in melanoma cells.
- Attenuates bleomycin-induced dermal fibrosis in vivo.
- Decreases kidney fibrosis in a mouse model.
- High oral bioavailability.
- Moderate half-life.
- Well tolerated in rats and dogs.
Medchemexpress LLC Pexidartinib hydrochloride | 2040295-03-0 | 99.8% | 454.28 | 200 MG
Pexidartinib hydrochloride is a potent, orally active, selective, and ATP-competitive inhibitor of colony stimulating factor 1 receptor (CSF1R or M-CSFR) and c-Kit. This compound induces cell apoptosis and demonstrates anti-cancer activity.
- Potent, orally active, selective, and ATP-competitive inhibitor.
- Targets colony stimulating factor 1 receptor (CSF1R) and c-Kit.
- Exhibits high selectivity over other related kinases.
- Induces cell apoptosis and demonstrates anti-cancer activity.
- IC50 of 10 nM for c-Kit and 20 nM for cFMS.
Cayman Chemical ArIstolochIc AcId 10mg
A PLA2 inhibitor (IC50 = 40 µM in human neutrophils); inhibits human synovial fluid PLA2-induced edema in a dose-dependent manner in vivo; inhibits hemolytic activity of the PLA2 enzymes TFV PL-X, TFV PL-Ia, and TFV PL-Ib from T. flavoviridis venom (IC50s = 4.6, 4.0, and 3.9 µM, respectively); enhances the edema-inducing activity of TFV PL-Ia and TFV PL-Ib; associated with progressive interstitial fibrosing nephropathy and upper urinary tract urothelial carcinomas
Sigma Aldrich Fine Chemicals Biosciences Carnosic acid from Rosmarinus officinalis >=91%, powder | 3650-09-7 | MFCD02259459 | 10MG
Carnosic acid from Rosmarinus officinalis >=91%, powder | Purity: >=91% | Mol Wt: 332.43 | 3650-09-7 | MFCD02259459 | 10MG
6-Aminochrysene 97%, Thermo Scientific™
CAS: 2642-98-0 Molecular Formula: C18H13N Molecular Weight (g/mol): 243.309 InChI Key: KIVUHCNVDWYUNP-UHFFFAOYSA-N Synonym: 6-aminochrysene,6-chrysenamine,chrysenex,chrysonex,6-amc,chrysen-6-ylamine,unii-i56l81bl2l,ccris 755,chrysene-6-ylamine,6-chrysenylamine PubChem CID: 17534 IUPAC Name: chrysen-6-amine SMILES: C1=CC=C2C(=C1)C=CC3=C2C=C(C4=CC=CC=C34)N
Phenanthrenequinone, tech., 80%, Thermo Scientific™
CAS: 84-11-7 Molecular Formula: C14H8O2 Molecular Weight (g/mol): 208.216 InChI Key: YYVYAPXYZVYDHN-UHFFFAOYSA-N Synonym: 9,10-phenanthrenequinone,phenanthrenequinone,9,10-phenanthrenedione,9,10-phenanthraquinone,phenanthraquinone,9,10-phenanthroquinone,9-10 phenanthrene quinone,unii-42l7bz8h74,ccris 7615,phenanthrene, 9,10-dihydro-9,10-dioxo PubChem CID: 6763 ChEBI: CHEBI:37454 IUPAC Name: phenanthrene-9,10-dione SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3C(=O)C2=O
![Benzo[a]pyrene 98%, Thermo Scientific™](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-50-32-8.jpg-250.jpg)
Benzo[a]pyrene 98%, Thermo Scientific™
CAS: 50-32-8 Molecular Formula: C20H12 Molecular Weight (g/mol): 252.32 MDL Number: MFCD00003602 InChI Key: FMMWHPNWAFZXNH-UHFFFAOYSA-N Synonym: benzo a pyrene,3,4-benzopyrene,benzo pqr tetraphene,3,4-benzpyrene,benzpyrene,benzo def chrysene,6,7-benzopyrene,benz a pyrene,3,4-benz a pyrene PubChem CID: 2336 ChEBI: CHEBI:29865 IUPAC Name: pentacyclo[10.6.2.0²,⁷.0⁹,¹⁹.0¹⁶,²⁰]icosa-1(18),2,4,6,8,10,12,14,16,19-decaene SMILES: C1=CC=C2C(=C1)C=C1C=CC3=CC=CC4=CC=C2C1=C34
