Saturated hydrocarbons

eMolecules​ 6760-99-2 | 8-azabicyclo[3.2.1]octane hydrochloride | Pharmablock | MFCD19982561 | 147.650 | C7H14ClN | 97.000 | Cl.C1CC2CCCC1N2 | 2.5g | 686924486

8-azabicyclo[3.2.1]octane hydrochloride | Pharmablock | 6760-99-2 | MFCD19982561 | 147.650 | C7H14ClN | 97.000 | Cl.C1CC2CCCC1N2 | 2.5g | 686924486

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Medchemexpress LLC Dynole 2-24 | 1416313-72-8 | 99.07% | C24H41N3 | 1 ML

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Dynole 2-24 is an indole-based dynamin GTPase inhibitor with an IC50 of 0.56 μM for dynamin I. It is nontoxic and demonstrates increased potency against dynamin I and II in vitro and in cells (IC₅₀(CME)=1.9 μM). The product also exhibits 4.4-fold selectivity for dynamin I and is an active in-cell inhibitor of clathrin-mediated endocytosis (CME).

• Indole-based dynamin GTPase inhibitor
• Nontoxic
• Increased potency against dynamin I and II in vitro and in cells
• 4.4-fold selectivity for dynamin I
• Active in-cell inhibitor of clathrin-mediated endocytosis (CME)

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Medchemexpress LLC I-287 | 2014368-93-3 | 99.4% | 565.04 | 1 ML

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I-287 is an orally active, selective PAR2 inhibitor that acts as a negative allosteric regulator on Gαq and Gα12/13 activity and their downstream effectors. It has been shown to reduce Complete Freund's adjuvant-induced inflammation in mice and can be used for inflammation/immunology research.

• Inhibits PAR2-mediated activation of Gαq and Gα12/13
• Inhibits PAR2-mediated ERK1/2 activation in HEK293 cells
• Inhibits PAR2-induced secretion of IL-8 cytokine in HCT-116 and A549 cells
• Reduces Complete Freund's adjuvant-induced inflammation in C57BL/6J mice

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Medchemexpress LLC 18-Azido-stearic acid | 1529763-58-3 | C18H35N3O2 | 100 MG

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18-Azido-stearic acid is a click chemistry reagent featuring an azide group. It functions as a hydrophobic bioconjugation linker, modifiable at the azido-position using Click-chemistry. This reagent can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules and ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN group-containing molecules.

• Click chemistry reagent with an azide group
• Functions as a hydrophobic bioconjugation linker
• Can be modified at the azido-position via Click-chemistry
• Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc)
• Participates in ring strain-promoted alkyne-azide cycloaddition (SPAAC)

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Medchemexpress LLC 2-Methylcyclopentane-1,3-dione | 765-69-5 | 100.0% | 112.13 | 10 MM 1 ML

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2-Methylcyclopentane-1,3-dione is a key intermediate for the total synthesis of steroids.

• Key intermediate for total synthesis of steroids.
• High purity (99.96%).
• Detailed solubility data for in vitro and in vivo applications.
• Comprehensive documentation including Data Sheet, SDS, and COA.
• Specific storage guidance for optimal stability.

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Medchemexpress LLC Hexadecane-1-thiol-d33 | 218956-22-0 | 98.0% | 291.71 | 10 MG

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Hexadecane-1-thiol-d33 is a deuterium-labeled version of Hexadecane-1-thiol. It is intended for research use only and is not sold to patients. Stable heavy isotopes like deuterium are integrated into drug molecules primarily for quantitation during drug development. Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.

• Can be used as a tracer.
• Can serve as an internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS.

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Medchemexpress LLC 2-Methylcyclopentane-1,3-dione | 765-69-5 | 100.0% | 112.13 | 50 G

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2-Methylcyclopentane-1,3-dione is a key intermediate for the total synthesis of steroids.

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Medchemexpress LLC MD-224 500mg | 2136247-12-4 | 500 MG

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MD-224 is a PROTAC small-molecule degrader of murine double minute 2 (MDM2) used in research to induce targeted protein degradation and study p53 pathway modulation. It is supplied as a high-purity solid with supporting analytical and safety documentation.

• High purity suitable for cellular and in vivo research.
• Contains an alkyne group for click chemistry conjugation.
• Characterized by LC-MS and supplied with a certificate of analysis and SDS.
• Available in multiple pack sizes and solution formats for flexible use.
• Potent activity at sub-nanomolar concentrations for MDM2 degradation.

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Medchemexpress LLC MD-224 100mg | 2136247-12-4 | 100 MG

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MD-224 is a small-molecule proteolysis-targeting chimera (PROTAC) that selectively degrades MDM2 for research applications. It shows high cellular potency and is supplied as a solid or as a 10 mM solution in DMSO.

• Selective MDM2 degrader for research use
• High potency in cellular assays (subnanomolar activity)
• Available as solid and 10 mM DMSO solution
• High purity suitable for biochemical studies
• Molecular formula C48H43Cl2FN6O6; molecular weight 889.80

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Medchemexpress LLC Dynole 2-24 | 1416313-72-8 | 99.1% | 371.60 g·mol⁻¹ | C24H41N3 | 5 MG

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Dynole 2-24 is an indole-based dynamin GTPase inhibitor used as a research reagent to inhibit dynamin I and II and to block clathrin-mediated endocytosis in cells.

• Potent inhibitor of dynamin I (IC50 = 0.56 μM).
• Active in cells to inhibit clathrin-mediated endocytosis (IC50 ≈ 1.9 μM).
• Shows selectivity for dynamin I over dynamin II (≈4.4-fold).
• High purity suitable for biochemical and cellular assays.
• Available in small research quantities as an oil for convenient handling.

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eMolecules​ 1246401-49-9 | (4R,4'R)-2,2'-(cyclopentane-1,1-diyl)bis(4-phenyl-4,5-dihydrooxazole) | Ambeed | MFCD28015892 | 360.457 | C23H24N2O2 | 98.000 | C1CCC(C1)(C1=N[C@@H](CO1)c1ccccc1)C1=N[C@@H](CO1)c1ccccc1 | 5g | 596568722

(4R,4'R)-2,2'-(cyclopentane-1,1-diyl)bis(4-phenyl-4,5-dihydrooxazole) | Ambeed | 1246401-49-9 | MFCD28015892 | 360.457 | C23H24N2O2 | 98.000 | C1CCC(C1)(C1=N[C@@H](CO1)c1ccccc1)C1=N[C@@H](CO1)c1ccccc1 | 5g | 596568722

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eMolecules​ 6760-99-2 | 8-Azabicyclo[3.2.1]octane hydrochloride | Ambeed | MFCD19982561 | 147.650 | C7H14ClN | 97.000 | Cl.C1CC2CCCC1N2 | 100mg | 525070970

8-Azabicyclo[3.2.1]octane hydrochloride | Ambeed | 6760-99-2 | MFCD19982561 | 147.650 | C7H14ClN | 97.000 | Cl.C1CC2CCCC1N2 | 100mg | 525070970

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Sigma Aldrich Fine Chemicals Biosciences Cyclopentane reagent grade, 98% | 287-92-3 | MFCD00001356 | 500ML

Cyclopentane reagent grade, 98% | Purity: 98% | Mol Wt: 70.13 | 287-92-3 | MFCD00001356 | 500ML

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Ambeed AMBEED

5000868885 OCTADECANE-910-DIONE 1GR

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Chemscene CHEMSCENE

5000576358 CYCLOHEPTANE CARBOXYLIC ACI 5G

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