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Filtered Search Results
Medchemexpress LLC Bay 65-1942 hydrochloride | 600734-06-3 | 99.4% | C22H26ClN3O4 | 100 MG
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Bay 65-1942 hydrochloride is an ATP-competitive and selective IKKβ inhibitor. This compound is intended for research use only. In vitro studies show that delivery of Bay 65-1942 prior to ischemia significantly decreases left ventricular infarct size. In vivo, it demonstrates synergistic inhibition of cell viability and induces caspase 3/7 activation when combined with AZD6244 in MYL-R cells.
- Acts as an ATP-competitive and selective IKKβ inhibitor
- Decreases left ventricular infarct size in vitro
- Attenuates CK-MB levels in vivo
- Demonstrates synergistic inhibition of cell viability with AZD6244
- Induces caspase 3/7 activation with AZD6244
- Suitable for research applications
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Selleck Chemical LLC NCT-503
NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor with the IC50 value of 2 5 M It is inactive against a panel of other dehydrogenases and shows minimal cross-reactivity in a panel of 168 GPCRs
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Medchemexpress LLC Tau protein (592-597), human TFA | 2703746-44-3 | 95.17% | 868.94 | 5 MG
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Tau protein (592-597), human TFA is a peptide fragment of human Tau protein. The dysfunction of Tau protein is involved in neurodegeneration and dementia. It is a white to off-white solid with a molecular weight of 868.94 and a chemical formula of C36H63F3N10O11. This product is for research use only.
- Purity of 95.17%
- Sequence is Ac-Val-Gln-Ile-Ile-Asn-Lys-NH2 (Ac-VQIINK-NH2)
- Solubility of ≥ 2 mg/mL (2.30 mM) in H2O
- Recommended storage for powder at -80°C for 2 years or -20°C for 1 year
- Recommended storage for solutions at -80°C for 6 months or -20°C for 1 month (sealed, away from moisture)
- Associated with Neuronal Signaling, Tau Protein, neurological disease, and neurodegenerative disease
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Sigma Aldrich Fine Chemicals Biosciences 3-Cyclohexene-1-methanol 98% | 1679-51-2 | MFCD00001574 | 5G
3-Cyclohexene-1-methanol 98% | Purity: 98% | Mol Wt: 112.17 | 1679-51-2 | MFCD00001574 | 5G
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Cayman Chemical cIs-10-NonadecenoIc AcId 100mg
A monounsaturated long chain fatty acid with potential antitumor and p53 inhibitory activity
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Chem-Impex International, Inc. 4-Octyne | MFCD00009471 | 5ML
4-Octyne, MFCD00009471, 5ML
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Medchemexpress LLC Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate | 1049004-32-1 | 280.17 | 5 G
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Bpin-Cyclohexene-COOEt, also known as Ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-cyclohexene-1-carboxylate, is a PROTAC linker belonging to the PEG class. It is designed for use in the synthesis of PROTAC molecules. This compound is a colorless to light yellow liquid.
- Intended for research use only.
- Unstable in solutions, requiring freshly prepared solutions for optimal use.
- Molecular weight of 280.17.
- Purity of 97.0%.
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Medchemexpress LLC Tau protein (592-597), human TFA | 2703746-44-3 | 95.2% | 868.94 | 50 MG
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Tau protein (592-597), human TFA is a peptide fragment of human Tau protein. The dysfunction of Tau protein is involved in neurodegeneration and dementia.
- Peptide fragment of human Tau protein.
- Involved in neurodegeneration and dementia research.
- Purity of 95.17%.
- Molecular weight of 868.94.
- White to off-white solid appearance.
- Powder storage: 2 years at -80°C, 1 year at -20°C.
- In solvent storage: 6 months at -80°C, 1 month at -20°C (sealed storage, away from moisture).
- Soluble in H2O at ≥ 2 mg/mL.
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Chem-Impex International, Inc. Ferrocene | MFCD00001427 | 100G
Ferrocene, MFCD00001427, 100G
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Cell Signaling Technology Phospho-FLT3 (Tyr589/591) (30D4) Rabbit mAb 20 ul
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Phospho-FLT3 (Tyr589/591) (30D4) Rabbit mAb 20 ul
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Aqua Solutions 1-OCTENE IN SOLVENT ISOPAR E
Aqua Solutions 0% 1-octene in Solvent (Isopar E) (600G)
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![Medchemexpress LLC 2-Pyrazinecarboxamide, 3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl- | 1232410-49-9 | 99.7% | 368.41 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000365548-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-Pyrazinecarboxamide, 3-amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl- | 1232410-49-9 | 99.7% | 368.41 | 10 MG
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VE-821 is a potent ATP-competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM. It demonstrates excellent selectivity for ATR with minimal cross-reactivity against related PIKKs such as ATM, DNA-PK, mTOR, and PI3Kγ. This compound enhances the sensitivity of pancreatic cancer cells to radiation and Gemcitabine, and inhibits radiation-induced G2/M arrest in cancer cells.
- Potent ATP-competitive inhibitor of ATR
- Excellent selectivity for ATR with minimal cross-reactivity
- Enhances sensitivity of pancreatic cancer cells to radiation and Gemcitabine
- Inhibits radiation-induced G2/M arrest in cancer cells
- Inhibits phosphorylation of Chk1 (Ser 345)
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Sigma Aldrich Fine Chemicals Biosciences 1,3,5-Undecatriene, mixture of 1,3(E),5(Z) and 1,3(E),5(E) isomers >=70%, stabilized | 16356-11-9 | MFCD00015699 | 1KG
1,3,5-Undecatriene, mixture of 1,3(E),5(Z) and 1,3(E),5(E) isomers >=70%, stabilized | Purity: >=70% | Mol Wt: 150.26 | 16356-11-9 | MFCD00015699 | 1KG
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Medchemexpress LLC DI-591 | 2245887-38-9 | 98.1% | 585.80 | C31H47N5O4S | 10MM 1ML
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DI-591 is a potent, high-affinity, cell-permeable inhibitor of the DCN1-UBC12 interaction that selectively inhibits cullin 3 neddylation. It is supplied for research use in both solution and solid forms and includes documented solubility and formulation protocols for in vitro and in vivo studies.
- Binds DCN1 and DCN2 with Ki values of 12 nM and 10.4 nM.
- Selective inhibition of cullin 3 neddylation.
- Cell-permeable small molecule suitable for cellular assays.
- Available as 10 mM solution in DMSO (1 mL) and as solid quantities.
- High purity (~98.1%) with supporting certificate of analysis.
- Soluble in DMSO (12.5 mg/mL); recommended in vivo formulations provided.
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Medchemexpress LLC 5-phenyl-1-pentyne (pent-4-ynylbenzene) | 1823-14-9 | MFCD00039813 | 98.0% | 144.21 g·mol⁻¹ | C11H12 | 500 MG
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5-Phenyl-1-pentyne is a terminal alkyne used as a building block and intermediate in organic synthesis and medicinal chemistry research. It is supplied as a high-purity small-molecule suitable for laboratory applications.
- High purity: 98.0%.
- CAS number: 1823-14-9.
- Chemical formula C11H12; molecular weight 144.21 g·mol⁻¹.
- Provided in milligram and gram pack sizes for research use.
- SMILES identifier available for structure confirmation.
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