Acrylic acids and derivatives
eMolecules 162760-96-5 | Medchem Express | WAY-100635 | 5mg | 415686488 | HY-10349 | MFCD00916243 | 422.573 | C25H34N4O2
Medchem Express | (R)-BDP9066 | 5mg | 705860183 | HY-111424A | 2284549-25-1 | 348.454 | C20H24N6
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Medchemexpress LLC (-)-Dizocilpine (maleate) | 121917-57-5 | C20H19NO4 | 100 MG
(-)-Dizocilpine maleate is a less active (-)-enantiomer of Dizocilpine. It functions as a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with a Ki of 211.7 nM and exhibits antidepressant effects.
- Less active (-)-enantiomer of Dizocilpine.
- Functions as a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with a Ki of 211.7 nM.
- Exhibits antidepressant effects.
- Significantly inhibits the uptake of norepinephrine, dopamine, and serotonin monoamine transporters in HEK cells in a dose-dependent manner.
- Induces rapid antidepressant effects in the social defeat stress model in male adult C57BL/6 mice at a dosage of 0.1 mg/kg via intraperitoneal injection.
Medchemexpress LLC Vicriviroc maleate | 599179-03-0 | 99.9% | 649.70 | 100 MG
Vicriviroc maleate is a potent, selective, oral bioavailable and CNS penetrated antagonist of CCR5, with a Ki of 2.5 nM. It also inhibits HIV-1 in PBMC cells, with IC90s of 3.3 nM (JrFL), 2.8 nM (ADA-M), 1.8 nM (301657), 4.9 nM (JV1083) and 10 nM (RU 570).
- Potent, selective, and oral bioavailable inhibitor of CCR5.
- Inhibits HIV-1 in PBMC cells.
- Demonstrates a mean IC50 and IC90 of 0.45 nM and 4 nM for a panel of HIV isolates.
- Exhibits good oral availability in rats and monkeys.
- No acute CNS or GI effects observed in rats.
- Shows weak activity against hERG (IC50, 5.8 μM).
- Inhibits chemotactic response to MIP-1α.
- Suppresses RANTES-induced signaling.
- Potently suppresses all tested viral isolates.
Medchemexpress LLC 5-Bromopyridin-2-ol | 13466-38-1 | 99.5% | C5H4BrNO | 25 G
5-Bromopyridin-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Biochemical reagent
- Suitable for life science related research
- Solid appearance
- White to yellow color
- Purity of 99.53%
- Molecular weight of 174.00
- Formula C5H4BrNO
Medchemexpress LLC Poly(acrylic acid) | 9003-01-4 | ≥95.0% | 10000-60000 | 1 G
Poly(acrylic acid) is a synthetic polymer known for its versatility in various applications. It is often used as a superabsorbent, dispersant, thickener, and emulsifier in a range of industries.
- Effective superabsorbent for liquids.
- Acts as a dispersant in aqueous solutions.
- Functions as a thickening agent.
- Useful as an emulsifier.
- Suitable for research use only.
Medchemexpress LLC Omigapil maleate | 200189-97-5 | 99.8% | 391.42 | 50 MG
Omigapil maleate (CGP3466B) is an orally active GAPDH nitrosylation inhibitor that can abrogate Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice. It has potential for research into Alzheimer's disease and congenital muscular dystrophy (CMD). Omigapil maleate also functions as an apoptosis inhibitor and a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide groups.
- Abrogates Aβ1-42-induced tau acetylation, memory impairment, and locomotor dysfunction in mice.
- Potential research area: Alzheimer's disease.
- Acts as an apoptosis inhibitor.
- Can be used for research on congenital muscular dystrophy (CMD).
- Click chemistry reagent with an Alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide groups.
Medchemexpress LLC 2-(Acetylamino)-2-deoxy-β-D-glucopyranosylamine | 4229-38-3 | MFCD00057751 | 98.4% | 220.22 g/mol | C8H16N2O5 | 1 MG
2-(Acetylamino)-2-deoxy-β-D-glucopyranosylamine is a carbohydrate-derived research reagent used in glycobiology and carbohydrate chemistry. Supplied as a purified solid (purity ≈98.4%), it is intended for use in glycan synthesis, enzymatic assays, and studies of protein-glycan recognition in basic research and biotechnology applications.
- High purity suitable for analytical and preparative work.
- Useful in glycan synthesis and modification studies.
- Suitable for enzymatic assays involving glycosyltransferases and glycosidases.
- Small molecular weight facilitates characterization by mass spectrometry and NMR.
- Available in small research quantities for laboratory workflows.
Medchemexpress LLC MAX-40279 hemifumarate | 2388506-43-0 | 99.6% | C22H23FN6OS·1/2C4H4O4 | 10MG
MAX-40279 hemifumarate is a small-molecule research inhibitor that targets FLT3 and FGFR kinases. It is orally active and retains activity against clinically relevant FLT3 mutants (for example, D835Y), making it suitable for studies of kinase inhibitor resistance and acute myelogenous leukemia (AML) signaling. It also inhibits NDRG1 phosphorylation at Ser330 and suppresses endothelial-to-mesenchymal transition (EndMT).
- Dual FLT3 and FGFR kinase inhibition
- Orally active and effective against FLT3 mutants such as D835Y
- Useful for AML research and studies of inhibitor resistance
- Inhibits NDRG1 phosphorylation at Ser330 and suppresses EndMT
- High purity (~99.6%) and fully characterized chemical properties
eMolecules 74397-12-9 | Medchem Express | Limaprost | 2mg | 446273163 | HY-B0683 | MFCD00868275 | 380.525 | C22H36O5
Medchem Express | Limaprost | 2mg | 446273163 | HY-B0683 | 74397-12-9 | MFCD00868275 | 380.525 | C22H36O5
Medchemexpress LLC 6-bromopyridin-3-amine | 13534-97-9 | MFCD01646116 | 99.5% | 173.01 g/mol | C5H5BrN2 | 500 G
6-Bromopyridin-3-amine is an organobromine intermediate and biochemical reagent used in organic synthesis and life-science research. It is supplied as a solid (C5H5BrN2) with a molecular weight of 173.01 g/mol and CAS number 13534-97-9. Documentation including a product data sheet, certificate of analysis, and safety data sheet are available to verify lot-specific properties and purity.
eMolecules 1211530-21-0 | (4-Bromopyridin-2-yl)acetic acid | Combi-Blocks, Inc. | MFCD09999987 | 216.034 | C7H6BrNO2 | 95.000 | OC(=O)Cc1cc(Br)ccn1 | 250mg | 569296423
(4-Bromopyridin-2-yl)acetic acid | Combi-Blocks, Inc. | 1211530-21-0 | MFCD09999987 | 216.034 | C7H6BrNO2 | 95.000 | OC(=O)Cc1cc(Br)ccn1 | 250mg | 569296423
Apexbio Technology LLC AS1842856,5mg CAS# 836620-48-5
AS1842856 is a specific Foxo1 inhibitor with IC50 of 30 nM. AS1842856 effectively inhibits autophagy[1]. AS1842856 only reduces Foxo1 activity by binding to Foxo1 without affecting its transcription and protein expression[2]. AS1842856 (0.1 μM) inhibits 70% of Foxo1-mediated promoter activity. AS1842856 may inhibit the activity of endogenous G6Pase and PEPCK by reducing the mRNA levels of G6Pase and PEPCK, which may inhibit the production of glucose in Fao cells[1]. In db/db mutant mice with diabetes, oral administration of AS1842856 can inhibit the genes related to gluconeogenesis of the liver, resulting in a large decrease in fasting blood glucose. In normal mice and db/db mice, treatment with AS1842856 can also suppress the increase in blood glucose levels caused by injection of pyruvate[1]. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC Oseltamivir acid-d3 | 1242184-43-5 | MFCD08703074 | 98.4% | 287.37 g/mol | C14H21D3N2O4 | 5 MG
Oseltamivir acid-d3 is a deuterium-labeled isotope analogue of oseltamivir acid (the active carboxylate metabolite). Provided as a solid reference standard, it is intended for analytical use including method development, isotope-dilution quantification, and pharmacokinetic studies. Typical identifiers: CAS 1242184-43-5; formula C14H21D3N2O4; molecular weight 287.37 g/mol; purity ~98.4%.
- Deuterium-labeled internal standard for LC-MS/MS quantification.
- High chemical purity suitable for quantitative analysis.
- Small solid format for convenient storage and handling.
- Appropriate for method validation and pharmacokinetic assays.
Medchemexpress LLC HY-14649 1g Medchemexpress, Retinoic acid CAS:302-79-4 Purity:>98%
Medchemexpress, HY-14649 1g Retinoic acid CAS:302-79-4 Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.