Amlodipine-1,1,2,2-d4 maleate is a deuterium-labeled calcium channel blocker that acts as an antianginal agent. It inhibits calcium influx by blocking voltage-dependent L-type calcium channels. This compound is utilized in research for high blood pressure and cancer, and can serve as a tracer or internal standard for quantitative analysis via NMR, GC-MS, or LC-MS. Deuterium labeling provides a means for precise quantitation in drug development and can influence drug pharmacokinetics and metabolism.
- Deuterium labeled calcium channel blocker
- Acts as an antianginal agent
- Inhibits calcium influx by blocking L-type channels
- Used in research for high blood pressure and cancer
- Functions as a tracer or internal standard for quantitative analysis
- Compatible with NMR, GC-MS, LC-MS
- Deuteration influences drug pharmacokinetics and metabolism