Boronic acid derivatives
![Frontier Specialty Chemicals 5g, (2-Methylpropyl)boronic acid, 97%, [84110-40-7], I7111 101.94 C4H11BO2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/default.jpg-250.jpg)
Frontier Specialty Chemicals 5g, (2-Methylpropyl)boronic acid, 97%, [84110-40-7], I7111 101.94 C4H11BO2
Compound: (2-Methylpropyl)boronic acid
CAS#: 84110-40-7
MDL#: MFCD00134156
Background: (2-Methylpropyl)boronic acid, also known as isobutylboronic acid, has been used to synthesize potent and selective dipeptidyl boronic acid proteasome inhibitors studied as therapeutics for cancer and inflammatory diseases, and in the preparation of isocoumarin analogs as gamma-secretase cleavage inhibitors. It is also used broadly in Suzuki-Miyaura reactions for the synthesis of complex pharmaceutical and agrochemical molecules.
Frontier Specialty Chemicals 25g, 3,5-Dichlorophenylboronic acid, 97%, [67492-50-6], D9266 190.82 C6H5BCl2O2
Compound: 3,5-Dichlorophenylboronic acid
CAS#: 67492-50-6
MDL#: MFCD00051935
Background: 3,5-Dichlorophenylboronic acid is used as an intermediate in pharmaceutical manufacturing and plays a role in Suzuki-Miyaura cross-coupling reactions essential for developing active pharmaceutical ingredients. It is also a reactant in trifluoromethylation, intramolecular aromatic carbenoid insertion, and cyanation reactions for synthesizing aromatic nitriles. It has additionally been used to facilitate transport of ribonucleosides across liposome membranes in biophysical research.
Frontier Specialty Chemicals 1g, Ethylboronic acid, 97%, [4433-63-0], E1104 73.89 C2H7BO2
Compound: Ethylboronic acid
CAS#: 4433-63-0
MDL#: MFCD01074536
Background: Ethylboronic acid is used as an intermediate in the synthesis of bioactive molecules with anticancer, antiviral, and antibacterial properties, and its derivatives have been studied as inhibitors of bacterial beta-lactamases involved in antibiotic resistance. It is widely used as a reagent in Suzuki-Miyaura cross-coupling reactions, forming carbon-carbon bonds with aryl and vinyl halides under mild conditions, and is also used in analytical chemistry techniques such as chromatography and mass spectrometry.
Frontier Specialty Chemicals 25g, 3,3-Diethoxy-1-propenylboronic acid pinacol ester, 95%, [153737-25-8], D10252 256.146 C13H25BO4
Compound: 3,3-Diethoxy-1-propenylboronic acid pinacol ester
CAS#: 153737-25-8
MDL#: MFCD03788737
Background: An acetal-protected propenylboronic ester used as a synthetic and pharmaceutical intermediate. It participates in Suzuki-Miyaura cross-coupling reactions, and the diethyl acetal group can be hydrolyzed after coupling to reveal an aldehyde for further derivatization.
Storage: Store at room temperature, under dry conditions.
Frontier Specialty Chemicals 5g, 4-(1-Naphthyl)phenyl boronic acid, 98%, [870774-25-7], N10084 248.084 C16H13BO2
Compound: 4-(1-Naphthyl)phenyl boronic acid
CAS#: 870774-25-7
MDL#: not listed
Background: A naphthyl-substituted phenylboronic acid used as a Suzuki-Miyaura coupling partner in materials science and pharmaceutical research. Naphthyl-biaryl building blocks of this type are commonly used in organic electronic and photoluminescent materials.
Storage: Store at room temperature, under dry conditions.
Frontier Specialty Chemicals 5g, Pyridine-3-boronic acid, 95%, [1692-25-7], P5775 122.92 C5H6BNO2
Compound: Pyridine-3-boronic acid
CAS#: 1692-25-7
MDL#: MFCD00674177
Background: Pyridine-3-boronic acid is a heteroaryl boronic acid used as a building block in Suzuki-Miyaura cross-coupling reactions to construct biaryl compounds containing a pyridine ring. It has been applied in phosphine-free and regioselective coupling methods, including tandem coupling-annulation sequences to build fused nitrogen heterocycles. It also supplies the 3-pyridyl unit used in the synthesis of the Bcr-Abl tyrosine-kinase inhibitor nilotinib.
Frontier Specialty Chemicals 1g, Quinoline-3-boronic acid, 95%, [191162-39-7], Q5061 172.98 C9H8BNO2
Compound: Quinoline-3-boronic acid
CAS#: 191162-39-7
MDL#: MFCD02183527
Background: Quinoline-3-boronic acid is a heteroaryl boronic acid used in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds. It has served as a reactant in the preparation of HIV protease inhibitors and has shown activity as an inhibitor of the Staphylococcus aureus NorA efflux pump. It is also used as a fluorescent sugar-sensing probe and as an intermediate in OLED materials.
Frontier Specialty Chemicals 1g, 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester, 98%, [847818-74-0], M2011 208.07 C10H17BN2O2
Compound: 1-Methyl-1H-pyrazole-5-boronic acid pinacol ester
CAS#: 847818-74-0
MDL#: MFCD05861380
Background: A methylated pyrazole boronic ester used as a coupling partner in Suzuki-Miyaura reactions. It has been used in the stereoselective preparation of arylamide compounds studied as cathepsin inhibitors, supporting medicinal chemistry research.
Storage: Store at 2-8°C, under dry conditions.
Frontier Specialty Chemicals 5g, Dibenzofuran-4-boronic acid, 97%, [100124-06-9], D5438 212.01 C12H9BO3
Compound: Dibenzofuran-4-boronic acid
CAS#: 100124-06-9
MDL#: MFCD00092336
Background: Dibenzofuran-4-boronic acid is a heteroaryl boronic acid used as a coupling partner in Suzuki-Miyaura cross-coupling reactions to form biaryl and heterobiaryl structures. It has been used to prepare glycosensors, as its fluorescence changes upon binding sugars under near-physiological conditions. It also serves as an intermediate in pharmaceutical, agrochemical, and OLED material synthesis.
Frontier Specialty Chemicals 5g, 3-Cyano-4-fluorophenylboronic acid, 97%, [214210-21-6], C10879 164.93 C7H5BFNO2
Compound: 3-Cyano-4-fluorophenylboronic acid
CAS#: 214210-21-6
MDL#: not listed
Background: A cyano- and fluoro-substituted phenylboronic acid used as a Suzuki-Miyaura coupling partner in pharmaceutical research. The nitrile group offers a reactive handle for further derivatization of downstream products.
Storage: Store at room temperature, under dry conditions.
Frontier Specialty Chemicals 1g, 3-Chloropyridine-4-boronic acid hydrate, 96%, [1256355-22-2], C1827 175.378 C5H7BClNO3
Compound: 3-Chloropyridine-4-boronic acid hydrate
CAS#: 1256355-22-2
MDL#: MFCD03453058
Background: 3-Chloropyridine-4-boronic acid hydrate is offered for experimental and research use as a synthetic building block in organic chemistry. Like related chloropyridine boronic acid derivatives, it is used in Suzuki-Miyaura cross-coupling reactions, which are essential for forming carbon-carbon bonds in pharmaceutical and agrochemical development.
Frontier Specialty Chemicals 5g, 3,3-Diethoxy-1-propenylboronic acid pinacol ester, 95%, [153737-25-8], D10252 256.146 C13H25BO4
Compound: 3,3-Diethoxy-1-propenylboronic acid pinacol ester
CAS#: 153737-25-8
MDL#: MFCD03788737
Background: An acetal-protected propenylboronic ester used as a synthetic and pharmaceutical intermediate. It participates in Suzuki-Miyaura cross-coupling reactions, and the diethyl acetal group can be hydrolyzed after coupling to reveal an aldehyde for further derivatization.
Storage: Store at room temperature, under dry conditions.
Frontier Specialty Chemicals 25g, Pyridine-3-boronic acid, 95%, [1692-25-7], P5775 122.92 C5H6BNO2
Compound: Pyridine-3-boronic acid
CAS#: 1692-25-7
MDL#: MFCD00674177
Background: Pyridine-3-boronic acid is a heteroaryl boronic acid used as a building block in Suzuki-Miyaura cross-coupling reactions to construct biaryl compounds containing a pyridine ring. It has been applied in phosphine-free and regioselective coupling methods, including tandem coupling-annulation sequences to build fused nitrogen heterocycles. It also supplies the 3-pyridyl unit used in the synthesis of the Bcr-Abl tyrosine-kinase inhibitor nilotinib.
Frontier Specialty Chemicals 25g, Ethylboronic acid, 97%, [4433-63-0], E1104 73.89 C2H7BO2
Compound: Ethylboronic acid
CAS#: 4433-63-0
MDL#: MFCD01074536
Background: Ethylboronic acid is used as an intermediate in the synthesis of bioactive molecules with anticancer, antiviral, and antibacterial properties, and its derivatives have been studied as inhibitors of bacterial beta-lactamases involved in antibiotic resistance. It is widely used as a reagent in Suzuki-Miyaura cross-coupling reactions, forming carbon-carbon bonds with aryl and vinyl halides under mild conditions, and is also used in analytical chemistry techniques such as chromatography and mass spectrometry.
Frontier Specialty Chemicals 5g, Quinoline-5-boronic acid, 98%, [355386-94-6], Q1089 172.98 C9H8BNO2
Compound: Quinoline-5-boronic acid
CAS#: 355386-94-6
MDL#: MFCD03095058
Background: Quinoline-5-boronic acid is used in the fabrication of organic semiconductors, where 5-substituted quinoline derivatives prepared via Suzuki coupling serve as electron-transport and hole-blocking materials in multilayer OLED architectures. It is also applied in the design of chemical sensors, in Suzuki-Miyaura coupling for drug discovery, and as a nitrogen donor ligand in metal-organic framework and fluorescent pH probe construction.