Organic phosphoric acids and derivatives
Medchemexpress LLC Triphenyl phosphate | 115-86-6 | MFCD00003031 | 99.7% | 326.28 g/mol | C18H15O4P | 1mL
Triphenyl phosphate is an organic phosphate flame retardant Triphenyl phosphate can disrupt placental tryptophan metabolism by activating MAOA/ROS/NF B leading to abnormal neurological behavior Triphenyl phosphate promotes oxidative stress by inducing inflammatory factors like nuclear factor kappa B (NF B) interleukin-6 and tumor necrosis factor Triphenyl phosphate can also cause allergic contact dermatitis[1][2]
Medchemexpress LLC Triphenyl phosphate | 115-86-6 | MFCD00003031 | 99.7% | 326.3 g/mol | C18H15O4P | 100g
Triphenyl phosphate is an organic phosphate flame retardant Triphenyl phosphate can disrupt placental tryptophan metabolism by activating MAOA/ROS/NF B leading to abnormal neurological behavior Triphenyl phosphate promotes oxidative stress by inducing inflammatory factors like nuclear factor kappa B (NF B) interleukin-6 and tumor necrosis factor Triphenyl phosphate can also cause allergic contact dermatitis[1][2]
Apexbio Technology LLC Estramustine phosphate sodium 52205-73-9 50mg
Estramustine phosphate sodium (CAS 52205-73-9) is an orally bioavailable small molecule that functions as an antimicrotubule agent Structurally related to estradiol it interacts with microtubule-associated proteins (MAPs) promoting microtubule disassembly and disrupting mitotic spindle formation This action interferes with mitosis ultimately leading to apoptotic cell death Widely studied in prostate cancer models estramustine phosphate sodium serves as a valuable tool for investigating mechanisms of cell cycle regulation mitotic arrest and apoptosis in oncological and cellular biology research settings
Apexbio Technology LLC Estramustine phosphate sodium 52205-73-9 10mg
Estramustine phosphate sodium (CAS 52205-73-9) is an orally bioavailable small molecule that functions as an antimicrotubule agent Structurally related to estradiol it interacts with microtubule-associated proteins (MAPs) promoting microtubule disassembly and disrupting mitotic spindle formation This action interferes with mitosis ultimately leading to apoptotic cell death Widely studied in prostate cancer models estramustine phosphate sodium serves as a valuable tool for investigating mechanisms of cell cycle regulation mitotic arrest and apoptosis in oncological and cellular biology research settings
Apexbio Technology LLC 3PO(Synonyms: 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, 3-(3-Pyridyl)-1-(4-pyridyl)-2-propen-1-one), 50mg, CAS: 13309-08-5; 18550-98-6.
3PO (CAS 13309-08-5 18550-98-6) is a small molecule inhibitor targeting 6-phosphofructo-2-kinase (PFKFB3) a regulatory enzyme involved in cellular glucose metabolism Its mode of action involves inhibiting PFKFB3 activity leading to reduced intracellular synthesis of fructose-2 6-bisphosphate and consequently decreased glycolytic flux By perturbing glucose metabolism 3PO modulates cellular proliferation growth and survival pathways The compound is widely used in cell and animal model studies exploring tumor metabolism metabolic disorders and immunometabolism
Apexbio Technology LLC 3PO(Synonyms: 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, 3-(3-Pyridyl)-1-(4-pyridyl)-2-propen-1-one), 100mg, CAS: 13309-08-5; 18550-98-6.
3PO (CAS 13309-08-5 18550-98-6) is a small molecule inhibitor targeting 6-phosphofructo-2-kinase (PFKFB3) a regulatory enzyme involved in cellular glucose metabolism Its mode of action involves inhibiting PFKFB3 activity leading to reduced intracellular synthesis of fructose-2 6-bisphosphate and consequently decreased glycolytic flux By perturbing glucose metabolism 3PO modulates cellular proliferation growth and survival pathways The compound is widely used in cell and animal model studies exploring tumor metabolism metabolic disorders and immunometabolism
Apexbio Technology LLC 3PO(Synonyms: 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, 3-(3-Pyridyl)-1-(4-pyridyl)-2-propen-1-one), 5mg, CAS: 13309-08-5; 18550-98-6.
3PO (CAS 13309-08-5 18550-98-6) is a small molecule inhibitor targeting 6-phosphofructo-2-kinase (PFKFB3) a regulatory enzyme involved in cellular glucose metabolism Its mode of action involves inhibiting PFKFB3 activity leading to reduced intracellular synthesis of fructose-2 6-bisphosphate and consequently decreased glycolytic flux By perturbing glucose metabolism 3PO modulates cellular proliferation growth and survival pathways The compound is widely used in cell and animal model studies exploring tumor metabolism metabolic disorders and immunometabolism
Apexbio Technology LLC 3PO(Synonyms: 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one, 3-(3-Pyridyl)-1-(4-pyridyl)-2-propen-1-one), 10mg, CAS: 13309-08-5; 18550-98-6.
3PO (CAS 13309-08-5 18550-98-6) is a small molecule inhibitor targeting 6-phosphofructo-2-kinase (PFKFB3) a regulatory enzyme involved in cellular glucose metabolism Its mode of action involves inhibiting PFKFB3 activity leading to reduced intracellular synthesis of fructose-2 6-bisphosphate and consequently decreased glycolytic flux By perturbing glucose metabolism 3PO modulates cellular proliferation growth and survival pathways The compound is widely used in cell and animal model studies exploring tumor metabolism metabolic disorders and immunometabolism
Apexbio Technology LLC Histamine Phosphate 51-74-1 10mM (in 1mL H2O)
Histamine Phosphate (51-74-1) is a small-molecule agonist targeting histamine receptors specifically the H1 and H2 receptors It is designed to activate these receptors thereby regulating vascular function and cellular signaling pathways Histamine Phosphate exerts its biological activity primarily through receptor-mediated signaling leading to vasodilation in arteries and capillaries In in vitro assays Histamine Phosphate demonstrates receptor activation with reported IC50 values for H1 and H2 receptors typically ranging from nanomolar to micromolar concentrations in receptor binding studies Based on these pharmacological properties Histamine Phosphate holds research potential in investigating vascular permeability inflammation gastric acid secretion and in characterizing histamine receptor signaling mechanisms
Apexbio Technology LLC NVP-BGJ398 phosphate 1310746-10-1 5mg
NVP-BGJ398 phosphate (CAS 1310746-10-1) is a potent selective inhibitor of fibroblast growth factor receptors (FGFRs) 1 2 and 3 exhibiting low nanomolar inhibitory activity (IC50 0 9 nM for FGFR1 1 nM for FGFR3 and 1 4 nM for FGFR2) It demonstrates markedly reduced potency against FGFR4 In cellular assays NVP-BGJ398 suppresses autophosphorylation of FGFRs leading to inhibition of downstream signaling pathways such as ERK1/2 The compound effectively reduces proliferation in cancer cell lines harboring FGFR genetic alterations and promotes cell-cycle arrest and apoptosis in cells with FGFR2 mutations NVP-BGJ398 is under investigation in oncology research including phase I clinical trials
Apexbio Technology LLC NVP-BGJ398 phosphate 1310746-10-1 200mg
NVP-BGJ398 phosphate (CAS 1310746-10-1) is a potent selective inhibitor of fibroblast growth factor receptors (FGFRs) 1 2 and 3 exhibiting low nanomolar inhibitory activity (IC50 0 9 nM for FGFR1 1 nM for FGFR3 and 1 4 nM for FGFR2) It demonstrates markedly reduced potency against FGFR4 In cellular assays NVP-BGJ398 suppresses autophosphorylation of FGFRs leading to inhibition of downstream signaling pathways such as ERK1/2 The compound effectively reduces proliferation in cancer cell lines harboring FGFR genetic alterations and promotes cell-cycle arrest and apoptosis in cells with FGFR2 mutations NVP-BGJ398 is under investigation in oncology research including phase I clinical trials
Apexbio Technology LLC NVP-BGJ398 phosphate 1310746-10-1 100mg
NVP-BGJ398 phosphate (CAS 1310746-10-1) is a potent selective inhibitor of fibroblast growth factor receptors (FGFRs) 1 2 and 3 exhibiting low nanomolar inhibitory activity (IC50 0 9 nM for FGFR1 1 nM for FGFR3 and 1 4 nM for FGFR2) It demonstrates markedly reduced potency against FGFR4 In cellular assays NVP-BGJ398 suppresses autophosphorylation of FGFRs leading to inhibition of downstream signaling pathways such as ERK1/2 The compound effectively reduces proliferation in cancer cell lines harboring FGFR genetic alterations and promotes cell-cycle arrest and apoptosis in cells with FGFR2 mutations NVP-BGJ398 is under investigation in oncology research including phase I clinical trials
Apexbio Technology LLC NVP-BGJ398 phosphate 1310746-10-1 10mg
NVP-BGJ398 phosphate (CAS 1310746-10-1) is a potent selective inhibitor of fibroblast growth factor receptors (FGFRs) 1 2 and 3 exhibiting low nanomolar inhibitory activity (IC50 0 9 nM for FGFR1 1 nM for FGFR3 and 1 4 nM for FGFR2) It demonstrates markedly reduced potency against FGFR4 In cellular assays NVP-BGJ398 suppresses autophosphorylation of FGFRs leading to inhibition of downstream signaling pathways such as ERK1/2 The compound effectively reduces proliferation in cancer cell lines harboring FGFR genetic alterations and promotes cell-cycle arrest and apoptosis in cells with FGFR2 mutations NVP-BGJ398 is under investigation in oncology research including phase I clinical trials
Medchemexpress LLC Pyridoxal phosphate | 54-47-7 | 99.95% | 500 UG
Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia. This product is for research use only.
- Severely inhibits DNA Polymerase and RNase H, leading to an immediate reduction in DNA synthesis.
- Conjugation to pyridoxal phosphate fully inhibits NEIL2.
- Activates the ERK/c-Jun signaling pathway and promotes IGFBP1 protein expression in HepG2 cells.
- Inhibits the proliferation of cancer cells SK-OV-3 and OVCAR-3.
- Alleviates Aβ25-35-induced spatial and long-term memory impairment in mouse models.
- Inhibits the formation of advanced glycation end-products (AGEs) and prevents the progression of diabetic nephropathy.
![Medchemexpress LLC L-homocysteine, S-[2-[(1-iminoethyl)amino]ethyl]-, phosphate | 438542-15-5 | 98.0% | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000231760.png-250.jpg)
Medchemexpress LLC L-homocysteine, S-[2-[(1-iminoethyl)amino]ethyl]-, phosphate | 438542-15-5 | 98.0% | 1 ML
GW274150 phosphate is the phosphate salt form of a selective inducible nitric oxide synthase (iNOS) inhibitor supplied for research use. It is provided as a 10 mM solution (1 mL) or as solid materials, and is accompanied by a datasheet, certificate of analysis, and safety data sheet.
- White to off-white solid or clear aqueous solution.
- Purity 98.0%.
- Molecular weight 317.30 g/mol.
- Chemical formula C8H20N3O6PS.
- Available as 10 mM 1 mL solution or in solid sizes (5 mg-100 mg, larger quantities by quote).
- Solubility: water 100 mg/mL; PBS 12.5 mg/mL (may require ultrasonic and warming).
- Storage: store solids at 4°C under inert gas; in solvent store at -80°C (6 months) or -20°C (1 month).
- For research use only; not for human use.