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1-Boc-azetidine-3-yl-methanol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) 1-Boc-azetidine-3-yl-methanol is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1] /sup
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(R)-Azetidine-2-carboxylic acid is the R-enantiomer of azetidine-2-carboxylic acid, a nonproteinogenic amino acid used as an ADC linker and in biochemical research. The material is supplied as a solid for laboratory use.
R-enantiomer of azetidine-2-carboxylic acid.
Nonproteinogenic amino acid and ADC linker.
Molecular formula C4H7NO2; molecular weight 101.10 g/mol.
Purity reported as 99.6% (data sheet) and 99.9% (alternate listing).
Appearance solid; store protected from light at 4°C; in solution store at -80°C (6 months) or -20°C (1 month).
Available in small laboratory pack sizes for research use.
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Fmoc-azetidine-3-carboxylic acid is an Fmoc-protected amino acid derivative used as a building block in peptide synthesis and as a linker component in ADC and PROTAC chemistry. It is supplied for research use and is characterized by defined molecular properties and high purity.
Fmoc-protected azetidine-3-carboxylic acid used in peptide synthesis.
Suitable as a cleavable ADC linker and for PROTAC linker chemistry.
High purity suitable for research applications.
Molecular formula C19H17NO4 and molecular weight 323.35.
Available in multiple pack sizes, including 25 g.
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1-Boc-azetidine-3-carboxylic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) 1-Boc-azetidine-3-carboxylic acid is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[2] /sup
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L-azetidine-2-carboxylic acid is a non-proteinogenic amino acid and a proline analog used as a research reagent in biochemical and cell biology studies. It is supplied as a high-purity solid for experiments involving protein synthesis, folding, and proline metabolism.
Non-proteinogenic amino acid and proline analog.
High purity (99.85%) suitable for research applications.
Molecular formula C4H7NO2 and molecular weight 101.10 g/mol.
Available as a 100 MG solid and in larger solid quantities.
Used in studies of protein synthesis, folding, and metabolism.
SDS, COA, and data sheet available for handling and quality information.
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1-Cbz-azetidine-3-carboxylic acid is an N-protected azetidine carboxylic acid used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and as an alkyl chain linker for PROTAC construction. It is supplied as a white to off-white solid with high purity suitable for medicinal chemistry and bioconjugation applications.
non-cleavable ADC linker for antibody-drug conjugates
alkyl chain-based PROTAC linker for targeted protein degradation
high purity (99.6%) suitable for synthesis and conjugation
soluble in DMSO at 100 mg/mL; may require ultrasonic
stable as powder at -20°C for long-term storage, or 4°C for shorter term
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L-azetidine-2-carboxylic acid is a non-proteinogenic amino acid and a proline analog used in biochemical and cell biology research to induce endoplasmic reticulum (ER) stress, protein misfolding, and related cellular pathways. It is provided as a solid for laboratory use and includes documentation such as COA and SDS.
Non-proteinogenic amino acid proline analog.
CAS number 2133-34-8.
Molecular formula C4H7NO2.
Molecular weight 101.10 g/mol.
Purity 99.9%.
Appearance solid, white to off-white.
Soluble in water (100 mg/mL with ultrasonic assistance); sparingly soluble in DMSO.
Storage 4°C, protect from light; in solution -80°C (6 months) or -20°C (1 month).
Available pack sizes include 1 G.
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Azetidine-2-carboxylic acid is a non-proteinogenic amino acid homologue of proline. It is found in common beets and can be misincorporated into proteins in place of proline in various species, including humans. It is described as a toxic and teratogenic agent and is intended for research use only.
Non-proteinogenic amino acid homologue of proline
Naturally found in common beets
Can be misincorporated into proteins
Toxic and teratogenic agent
Intended for research use only
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Ethyl azetidine-3-carboxylate hydrochloride is the hydrochloride salt of ethyl azetidine-3-carboxylate, used as a synthetic building block in medicinal chemistry and antibody-drug conjugate linker synthesis.
Hydrochloride salt supplied as a powder.
Purity 98.0% (NMR).
Molecular formula C6H12ClNO2 and molecular weight 165.62 g/mol.
Available in laboratory-scale quantities, including 5 g packs.
Recommended storage -20°C per certificate of analysis.
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1-Boc-D-azetidine-2-carboxylic acid is a Boc-protected D-azetidine derivative used as a versatile building block in medicinal chemistry and small-molecule synthesis. It serves as an intermediate for preparation of biologically active compounds and is supplied with analytical documentation suitable for research and development use.
High purity (98.96%) with certificate of analysis available.
Boc-protected azetidine scaffold for selective synthetic transformations.
Available in multiple pack sizes, including bulk 25 g packaging.
Documented storage conditions for stability in solid and solution forms.
Accompanied by SDS and handling instructions for laboratory use.
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