Azobenzenes

Medchemexpress LLC Lys006 hydrochloride | 2619563-79-8 | 429.23 | 50 MG

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LYS006 hydrochloride is a potent inhibitor of leukotriene A4 hydrolase (LTA4H) with an IC50 of 2 nM. It is extracted from patent WO2015092740A1, example 29, and is for research use only. It can be used for the research of inflammatory and autoimmune disorders.

• Potent inhibitor of LTA4H hydrolase
• IC50 of 2 nM
• Used for research on inflammatory and autoimmune disorders
• Currently in Phase 2 clinical trials for inflammatory acne, ulcerative colitis, hidradenitis suppurativa, and non-alcoholic fatty liver disease/nonalcoholic steatohepatitis

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Medchemexpress LLC WWL113 | 947669-86-5 | 99.7% | 466.53 | 1 ML

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WWL113 is a selective and orally active Ces3 and Ces1f inhibitor, with IC50 values of 120 nM and 100 nM for Ces3 and Ces1f, respectively. It appears to show excellent selectivity for the 60-kDa serine hydrolase (or hydrolases).

• Inhibits mouse recombinant Ces1, Ces1c, and ABHD6 at 10 μM.
• Significantly increases UCP1 protein expression in brown adipocytes at 1 μM.
• Has a partial, statistically significant inhibitory effect on blocking the buildup of PGE2.
• Results in major improvement of multiple features of metabolic syndrome and ameliorated obesity-diabetes in mice with lowered levels of nonesterified free fatty acids (NEFAs), triglycerides (TGs), total cholesterol and fasted glucose as well as enhanced glucose tolerance (30 mg/kg, orally once a day).
• Ameliorates obesity-diabetes in mice.

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Medchemexpress LLC Valategrast (R-411 free base) | 220847-86-9 | 97.1% | C30H32Cl3N3O4 | 50 MG

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Valategrast (R-411 free base) is a potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist. It is being investigated for its potential in treating Chronic Obstructive Pulmonary Disease (COPD) and asthma. It contains a common l-phenylalanine-N-aroyl motif where the carboxylic acid binds to the metal ion in the metal-ion-dependent adhesion site (MIDAS).

• Potent and orally active integrin α4β1 (VLA-4) and α4β7 dual antagonist.
• Potential for treating Chronic Obstructive Pulmonary Disease (COPD).
• Potential for treating asthma.
• Contains an l-phenylalanine-N-aroyl motif for binding to the metal ion in the MIDAS site.

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Sigma Aldrich Fine Chemicals Biosciences Azobenzene 98% | 103-33-3 | MFCD00003022 | 25G

Azobenzene 98% | Purity: 98% | Mol Wt: 182.22 | 103-33-3 | MFCD00003022 | 25G

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eMolecules​ AstaTech / (4-ETHYLTHIAZOL-2-YL)METHANAMINE DIHYDROCHLORIDE / 1g / 718080323 / AT34437 / 95.000 / 1262771-85-6 / MFCD09864312 / 215.140 / C6H12Cl2N2S

AstaTech / (4-ETHYLTHIAZOL-2-YL)METHANAMINE DIHYDROCHLORIDE / 1g / 718080323 / AT34437 / 95.000 / 1262771-85-6 / MFCD09864312 / 215.140 / C6H12Cl2N2S

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eMolecules​ AstaTech / 14-DIAZASPIRO[5.5]UNDECAN-5-ONE / 1g / 718056409 / AT28656 / 95.000 / 86047-86-1 / MFCD07373481 / 168.240 / C9H16N2O

AstaTech / 14-DIAZASPIRO[5.5]UNDECAN-5-ONE / 1g / 718056409 / AT28656 / 95.000 / 86047-86-1 / MFCD07373481 / 168.240 / C9H16N2O

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Medchemexpress LLC Chromeceptin 10mg | 331859-86-0 | 10 MG

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Chromeceptin is a small-molecule IGF signaling pathway inhibitor for research use that suppresses IGF2 expression and reduces phosphorylation of AKT and mTOR. Supplied as a high-purity solid suitable for biochemical and cell-based studies.

• High purity suitable for biochemical assays and cell-based studies.
• Inhibits IGF signaling and suppresses IGF2 expression.
• Reduces phosphorylation of AKT and mTOR in target cells.
• Available as a 10 mg powder with recommended low-temperature storage.
• Soluble in common organic solvents for assay preparation.

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Medchemexpress LLC Protostemotinine | 169534-85-4 | 99.4% | 415.48 | C23H29NO6 | 10 MG

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Protostemotinine is a natural alkaloid isolated from the roots and rhizomes of Stemona sessilifolia and supplied for research use. Analytical data and safety information are provided to support laboratory handling and small-scale experiments.

• Natural alkaloid isolated from Stemona sessilifolia.
• High purity (99.4%) with verified analytical data.
• Molecular formula C23H29NO6; molecular weight 415.48.
• CAS number 169534-85-4 for unambiguous identification.
• Soluble in DMSO (25 mg/mL); sonication recommended.
• COA and SDS available for download.
• Packaged as 10 mg for small-scale research use.

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eMolecules​ N-Succinimidyl 4-[4-(dimethylamino)phenylazo]benzoate | 146998-31-4 | MFCD00467415 | 1g

Chem-Impex | N-Succinimidyl 4-[4-(dimethylamino)phenylazo]benzoate | 1g | 386904015 | 31318 | | 146998-31-4 | MFCD00467415 | 366.377 | C19H18N4O4

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Medchemexpress LLC Cdc7-IN-5 | 1402057-86-6 | 96.7% | 50 MG

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Cdc7-IN-5 is a potent Cdc7 kinase inhibitor extracted from patent WO2019165473A1. Cdc7 is a serine-threonine protein kinase enzyme which is essential for the initiation of DNA replication in the cell cycle.

• Potent Cdc7 kinase inhibitor.
• Essential for the initiation of DNA replication in the cell cycle.
• For research use only.

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Medchemexpress LLC Cdc7-IN-5 | 1402057-86-6 | 96.0% | 100 MG

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Cdc7-IN-5 is a potent Cdc7 kinase inhibitor. This compound is extracted from patent WO2019165473A1 and targets Cdc7, a serine-threonine protein kinase enzyme essential for initiating DNA replication in the cell cycle.

• Potent Cdc7 kinase inhibitor
• Extracted from patent WO2019165473A1
• Targets serine-threonine protein kinase enzyme Cdc7
• Essential for DNA replication initiation
• Appearance: solid, white to light yellow
• Molecular weight: 445.47
• Molecular formula: C25H23N3O5

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Medchemexpress LLC Methylglyoxal-bis(guanylhydrazone) | 459-86-9 | MFCD00067519 | ≥98.0% | 184.20 g·mol⁻¹ | C5H12N8 | 50 MG

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Mitoguazone (methylglyoxal-bis(guanylhydrazone)) is a small-molecule research reagent that competitively inhibits S-adenosyl-methionine decarboxylase (SAMDC) and disrupts polyamine biosynthesis. It is used in biochemical and cellular studies to probe polyamine-dependent processes, mitochondrial effects, and apoptosis. Chemical identifiers include CAS 459-86-9, formula C5H12N8, and molecular weight 184.20 g·mol⁻¹.

• Competitive inhibitor of S-adenosyl-methionine decarboxylase (SAMDC).
• Disrupts polyamine biosynthesis for pathway and apoptosis research.
• Reported to be brain-penetrant and useful in cellular assays.
• Characterized chemical identifiers: CAS 459-86-9, formula C5H12N8, MW 184.20 g·mol⁻¹.
• Recommended storage sealed and away from moisture; in solvent: -80°C long-term, -20°C short-term.
• Reported supplier purity commonly ≥98% for research-grade material.

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Medchemexpress LLC Apiopaeonoside | 100291-86-9 | 99.8% | 460.43 g/mol | C20H28O12 | 10 MG

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Apiopaeonoside is a naturally occurring glycoside isolated from the root of Paeonia suffruticosa, provided as a research-grade reagent for biochemical and pharmacological studies. It has formula C20H28O12, a molecular weight of 460.43 g/mol, and is supplied in high purity for experimental applications.

• High purity: 99.8%.
• Molecular formula C20H28O12.
• Molecular weight 460.43 g/mol.
• Available as solid and as 10 mM solution in DMSO.
• Intended for biochemical and pharmacological research use.

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eMolecules​ ChemScene / Irondisulfide(Ironpyrite) / 5g / 601109816 / CS-0111192 / 0.000 / 12068-85-8 / [null] / 119.970 / FeS2

ChemScene / Irondisulfide(Ironpyrite) / 5g / 601109816 / CS-0111192 / 0.000 / 12068-85-8 / [null] / 119.970 / FeS2

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Medchemexpress LLC Cadrofloxacin 25mg | 153808-85-6 | 25 MG

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Cadrofloxacin is an orally active fluoroquinolone antibiotic supplied for research use only. It exhibits activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria and is provided as a solid powder for laboratory research and assay development.

• Orally active fluoroquinolone antibacterial agent.
• Active against aerobic and anaerobic Gram-positive and Gram-negative bacteria.
• Supplied as a solid powder suitable for research use.
• Molecular formula C19H20F3N3O4; molecular weight 411.38 g·mol⁻¹.
• Typical purity approximately 98.2% as reported by the manufacturer.

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