Azobenzenes
eMolecules 104-23-4 | 4'-Aminoazobenzene-4-sulphonic acid | Combi-Blocks | MFCD00035778 | 277.300 | C12H11N3O3S | 97.000 | Nc1ccc(cc1)\N=N\c1ccc(cc1)S(O)(=O)=O | 1g | 205402053
4'-Aminoazobenzene-4-sulphonic acid | Combi-Blocks | 104-23-4 | MFCD00035778 | 277.300 | C12H11N3O3S | 97.000 | Nc1ccc(cc1)\N=N\c1ccc(cc1)S(O)(=O)=O | 1g | 205402053
Medchemexpress LLC 5-hydroxy-2-methyl-7-(thiiran-2-ylmethoxy)-4H-chromen-4-one | 2133499-85-9 | MFCD32201069 | 99.7% | 264.30 g/mol | C13H12O4S | 10MG
HSP27 inhibitor J2 is a small-molecule research reagent that targets heat shock protein 27 (HSP27), inducing abnormal HSP27 dimer formation and disrupting polymer assembly. It is provided as a solid and as a 10 mM solution in DMSO for biochemical and cellular studies; not for clinical use.
- Selective inhibitor of HSP27 for in vitro research.
- High purity: 99.7%.
- Molecular weight: 264.30 g/mol.
- Chemical formula: C13H12O4S.
- Available as solid and 10 mM solution in DMSO.
- Physical form: off-white to light yellow solid.
- Recommended storage: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
eMolecules 1452458-86-4 | Medchem Express | Nacubactam | 5mg | 628192271 | HY-109008 | 324.31 | C9H16N4O7S
Medchem Express | DSR-141562 | 5mg | 532149366 | HY-136569 | 2007975-22-4 | 414.429 | C19H25F3N4O3
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Cayman Chemical Sulfasalazine, Purity: ≥98%, CAS: 599-79-1, 5 g
A prodrug form of 5-aminosalicylic acid; inhibits TNF-α and LPS-induced NF-κB activation in SW620 colon cancer cells at 0.1-5 mM; inhibits cystine uptake through the system xc- cysteine-glutamate transporter at 0.25 mM and inhibits the growth of U-87MG glioma cells in an NF-κB independent manner at 0.25-1 mM; decreases diarrhea, increases food intake, and reverses body weight decreases in a mouse model of colitis at 100 mg/kg; suppresses antigen-induced arthritis in mice
Medchemexpress LLC Orismilast | 1353546-86-7 | 99.9% | 510.29 g·mol⁻¹ | C19H15Cl2F2NO7S | 5 MG
Orismilast is an orally active, selective phosphodiesterase 4 (PDE4) inhibitor used in preclinical research on inflammatory diseases. It demonstrates potent activity against PDE4B and PDE4D subtype splice variants and is supplied as a high-purity research compound.
- Selective phosphodiesterase 4 (PDE4) inhibitor.
- Orally active compound suitable for inflammatory disease research.
- Potent inhibition of PDE4B and PDE4D subtype splice variants.
- High purity solid supplied in a 5 mg package.
- Molecular weight 510.29 g·mol⁻¹; formula C19H15Cl2F2NO7S.
Medchemexpress LLC Olean-12-en-28-oic acid, 3-[(O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl)oxy]- | 340963-86-2 | 5 MG
Araloside V is a chemical compound supplied as a white to off-white solid with a high purity of 99.59% as determined by HPLC. It is intended for research use only and has not been fully validated for medical applications.
- High purity (99.59% by HPLC)
- White to off-white solid appearance
- Stable at 4°C for sealed storage away from moisture
- Can be stored in solvent at -80°C for 6 months or -20°C for 1 month (sealed, away from moisture)
- Suitable for research applications
eMolecules 83846-85-9 | Phenyl(4-(p-tolylthio)phenyl)methanone | Ambeed | MFCD00055651 | 304.410 | C20H16OS | 98.000 | Cc1ccc(Sc2ccc(cc2)C(=O)c2ccccc2)cc1 | 5g | 600847986
Phenyl(4-(p-tolylthio)phenyl)methanone | Ambeed | 83846-85-9 | MFCD00055651 | 304.410 | C20H16OS | 98.000 | Cc1ccc(Sc2ccc(cc2)C(=O)c2ccccc2)cc1 | 5g | 600847986
Medchemexpress LLC Mind4-19 | 129544-85-0 | 99.93% | 373.47 | 50 MG
MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. It can be used for researching Huntington's disease.
- Potent SIRT2 inhibitor.
- Exhibits an IC50 value of 7.0 μM for SIRT2.
- Applicable for research into Huntington's disease.
eMolecules 185259-85-2 | Medchem Express | GR-46611 | 5mg | 724441955 | HY-101248 | MFCD00953517 | 377.488 | C23H27N3O2
Medchem Express | PARP10|15-IN-3 | 5mg | 761041080 | HY-146502 | 2892064-88-7 | 274.320 | C15H18N2O3
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Medchemexpress LLC Voacamine | 3371-85-5 | 5 MG
Voacamine is an indole alkaloid with cannabinoid 1 (CB1) antagonistic activity. It can inhibit nuclear translocation. Voacamine enhances the effect of Doxorubicin by interfering with P-glycoprotein (P-gp) function. It promotes apoptosis-independent autophagic cell death in human osteosarcoma cells. Voacamine activates the mitochondrial-associated apoptosis signaling pathway and inhibits the PI3K/Akt/mTOR signaling pathway to suppress breast cancer progression. Additionally, Voacamine inhibits EGFR to exert oncogenic activity against colorectal cancer.
- Indole alkaloid
- Acts as a cannabinoid 1 (CB1) antagonist
- Enhances Doxorubicin effect through P-gp interference
- Promotes autophagic cell death in osteosarcoma cells
- Suppresses breast cancer progression by inhibiting PI3K/Akt/mTOR signaling
- Exerts oncogenic activity against colorectal cancer by inhibiting EGFR
Medchemexpress LLC GPX4-IN-3 | 2761004-85-5 | 99.8% | C29H24ClN3O3S | 100 MG
GPX4-IN-3 is a potent and selective glutathione peroxidase 4 (GPX4) inhibitor and a selective ferroptosis inducer. It demonstrates significant inhibition of GPX4 and effectively induces ferroptosis in various cell lines, showing a strong ability to increase lipid peroxides. This compound also exhibits antitumor activity and good biological safety in preclinical models, effectively suppressing tumor growth.
- Potent glutathione peroxidase 4 (GPX4) inhibitor
- Selective ferroptosis inducer
- Increases lipid peroxide levels
- Induces ferroptosis with satisfactory selectivity
- Increases reactive oxygen species (ROS) levels in 4T1 cells
- Exhibits antitumor activity
- Good biological safety in vivo
- Suppresses tumor growth in mouse xenograft models
Medchemexpress LLC 4-hydroxy-2-methyl-1,1-dioxo-N-(1,3-thiazol-2-yl)-1λ6,2-benzothiazine-3-carboxamide | 34042-85-8 | MFCD00866053 | 100.0% | 337.37 g/mol | C13H11N3O4S2 | 25 MG
Sudoxicam is a reversible, orally active cyclooxygenase (COX) antagonist and a non-steroidal anti-inflammatory compound of the enol-carboxamide class supplied for research and analytical use only. It demonstrates anti-inflammatory, anti-edema, and antipyretic activity and is provided as a solid and in DMSO solution formulations for laboratory studies.
- Reversible, orally active COX antagonist.
- High reported purity suitable for analytical work.
- Chemical formula C13H11N3O4S2 and molecular weight 337.37 g/mol.
- Soluble in DMSO; ultrasonic warming may improve solubility.
- Stable as powder at -20°C for long-term storage; in solvent storage guidelines provided.