Azobenzenes
Medchemexpress LLC SU5205 | 3476-86-6 | 98.02% | 239.24 | 50 MG
SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM. It inhibits ligand-induced endothelial mitogenesis for VEGF with an IC50 of 5.1 μM.
- Inhibitor of VEGFR2 (FLK-1)
- Inhibits ligand-induced endothelial mitogenesis for VEGF
Medchemexpress LLC Regaloside C | 117591-85-2 | 10 MG
Regaloside C is an anti-inflammatory agent and antioxidant that scavenges ABTS and DPPH free radicals. It targets multiple molecules, including TNF-α, MMP-2, ERα, AKT1, TLR4, and HSP90-α, making it applicable for research related to inflammatory diseases.
- Anti-inflammatory agent
- Antioxidant properties
- Scavenges ABTS and DPPH free radicals
- Targets TNF-α, MMP-2, ERα, AKT1, TLR4, and HSP90-α
- Suitable for inflammatory disease research
- Molecular weight of 416.38
- Chemical formula of C18H24O11
- Off-white to yellow solid appearance
- Originates from Gramineae Secale cereale plants
- Potent scavenger of ABTS cationic radicals (IC50 of 139.0 μM)
- Potent scavenger of DPPH anionic radicals (IC50 of 51.6 μM)
eMolecules Ambeed / Dimethyl pyridine-25-dicarboxylate / 1g / 552704469 / A316473 / / 881-86-7 / MFCD00034767 / 195.174 / C9H9NO4
Ambeed / Dimethyl pyridine-25-dicarboxylate / 1g / 552704469 / A316473 / / 881-86-7 / MFCD00034767 / 195.174 / C9H9NO4
eMolecules AstaTech / ISOPROPYL(2-NITROPHENYL)SULFANE / 0.25g / 434269003 / W12996 / 95.000 / 70415-85-9 / MFCD13689000 / 197.250 / C9H11NO2S
AstaTech / ISOPROPYL(2-NITROPHENYL)SULFANE / 0.25g / 434269003 / W12996 / 95.000 / 70415-85-9 / MFCD13689000 / 197.250 / C9H11NO2S
Medchemexpress LLC Atuliflapon (AZD5718) | 2041075-86-7 | 99.0% | 10 MG
Atuliflapon is an orally active FLAP (5-lipoxygenase activating protein) inhibitor used as a research tool to modulate leukotriene production and study inflammatory and cardiovascular biology.
- Oral FLAP inhibitor with low-nanomolar potency in enzyme/binding assays.
- Inhibits LTB4 production in human whole blood (IC50 ≈ 39 nM); binding Kd ≈ 4.4 nM in assay reports.
- Chemical formula C24H26N6O3 and molecular weight 446.50 g/mol.
- High purity (≈99.0%) suitable for in vitro studies.
- Available as solids and as DMSO solutions (examples: 10 mg solid; 10 mM, 1 mL in DMSO).
Medchemexpress LLC SU5205 | 98.4% | 100 MG
SU5205 is an inhibitor of VEGFR2 (FLK-1), with an IC50 of 9.6 μM.
- No clinical development reported
Medchemexpress LLC 3-(benzylthio)-5-(phenoxymethyl)-4-phenyl-4H-1,2,4-triazole | 129544-85-0 | 99.9% | C22H19N3OS | 10MG
MIND4-19 is a small-molecule SIRT2 inhibitor (IC50 7.0 μM) used as a research tool in studies of neurodegeneration, including Huntington's disease. The compound is a solid, white to off-white material with formula C22H19N3OS and a molecular weight of 373.47 g·mol⁻¹; it is supplied with high purity and storage recommendations to protect activity.
- Potent SIRT2 inhibition (IC50 7.0 μM).
- High chemical purity (>99.9%).
- Solid, white to off-white appearance for easy handling.
- Suitable for neurodegeneration and SIRT2 biology research.
- Storage conditions provided to preserve stability and activity.
Medchemexpress LLC HKOCl-4 (BXY2142) | 2031170-85-9 | 95.1% | 1 MG
HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe designed for the detection of hypochlorous acid, offering excellent sensitivity and selectivity. It possesses a longer absorption wavelength and improved pH stability compared to fluorescein-based probes. This probe is intended for research use only.
- Detection of hypochlorous acid
- Excellent sensitivity and selectivity
- Longer absorption wavelength
- Improved pH stability
- Excitation wavelength: 530 nm
- Emission wavelength: 557 nm
- Ultra-fast response to HOCl (reaches plateau within 2 min)
- More than 20-fold increase in fluorescence intensity over other analytes
- Non-toxic in living cells at concentrations up to 50 μM in RAW264.7 macrophages
Medchemexpress LLC Olean-12-en-28-oic acid, 3-[(O-β-D-glucopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→3)]-β-D-glucopyranosyl)oxy]- | 340963-86-2 | 5 MG
Araloside V is a chemical compound supplied as a white to off-white solid with a high purity of 99.59% as determined by HPLC. It is intended for research use only and has not been fully validated for medical applications.
- High purity (99.59% by HPLC)
- White to off-white solid appearance
- Stable at 4°C for sealed storage away from moisture
- Can be stored in solvent at -80°C for 6 months or -20°C for 1 month (sealed, away from moisture)
- Suitable for research applications
Medchemexpress LLC C-021 | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 25 MG
C-021 is a small-molecule CCR4 antagonist supplied for research use. It inhibits CCR4-mediated chemotaxis in human and mouse cells and blocks CCL22-induced GTPγS binding, making it suitable for biochemical and cellular assays.
- Target: CCR4 (GPCR), suitable for immunology and GPCR research.
- Potent CCR4 antagonist with reported IC50s of 140 nM (human chemotaxis), 39 nM (mouse chemotaxis), and 18 nM in GTPγS binding assays.
- Molecular formula C27H41N5O2 and molecular weight 467.65 g/mol.
- Reported purity 99.95% and solid appearance (off-white to light yellow).
- Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human or animal therapeutic use.
Medchemexpress LLC Benzenesulfonamide, N-[(4-bromophenyl)methyl]-4-chloro-N-[(3R)-hexahydro-2-oxo-1H-aze | 851600-86-7 | 99.5% | C19H20BrClN2O3S | 100 MG
ELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor, demonstrating 51-fold selectivity for PS1 with EC50s of 12 nM for PS1 and 656 nM for PS2. It functions as a classic γ-secretase inhibitor, selectively inhibiting Aβ production over Notch signaling in cells. Oral administration *in vivo* leads to an acute reduction of brain Aβ in models of Alzheimer's disease.
- Amyloid precursor protein (APP) selective γ-secretase inhibitor
- Exhibits differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase
- Demonstrates 51-fold selectivity for PS1
- Selectively inhibits Aβ production over Notch signaling in cells
- Displaces an active site directed inhibitor *in vitro*
- Leads to acute reduction of brain Aβ *in vivo* in Alzheimer's disease models
Medchemexpress LLC 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenylethanone | 274925-86-9 | MFCD09954136 | 99.9% | 273.24 | C14H11NO5 | 50 MG
Nebicapone is a reversible catechol-O-methyltransferase (COMT) inhibitor provided as a solid research compound for in vitro and in vivo studies. It is used to study COMT-mediated metabolism of L-DOPA and related pharmacology, and is supplied with characterization data and storage recommendations for experimental stability.
- Reversible COMT inhibitor for research use.
- Reported purity 99.9%.
- Molecular weight 273.24 g/mol.
- Physical form solid powder.
- High solubility in DMSO (≥100 mg/mL) and formulated in vivo solubility ≥2.5 mg/mL in 10% DMSO/40% PEG300/5% Tween-80/45% saline.
- Recommended storage 4°C protected from light; in solution store at -80°C up to 6 months or -20°C up to 1 month.
eMolecules Medchem Express / Firibastat / 5mg / 599150364 / HY-109058 / / 648927-86-0 / MFCD20921962 / 368.500 / C8H20N2O6S4
Medchem Express / Firibastat / 5mg / 599150364 / HY-109058 / / 648927-86-0 / MFCD20921962 / 368.500 / C8H20N2O6S4