Azobenzenes
Medchemexpress LLC 2-(3-oxo-1-phenyl-3-(4-(trifluoromethyl)phenyl)propyl)malonic acid | 1221962-86-2 | 98.0% | 10 MG
PS210 is a small-molecule activator of PDK1 provided for research use. It binds the PIF-binding pocket of PDK1 and is supplied as a solid or as a 10 mM solution in DMSO for in vitro studies.
- Small-molecule PDK1 activator for research use.
- Solid and 10 mM DMSO solution formats available.
- High purity (~98.0%) confirmed by supplier analytical data.
- Molecular weight 380.31 g/mol; formula C19H15F3O5.
- Supplied in small milligram quantities suitable for biochemical assays.
Medchemexpress LLC 1-(3-fluorophenyl)-5-methylpyridin-2(1H)-one | 848353-85-5 | 99.8% | 50 MG
Fluorofenidone (AKF-PD) is an orally active small-molecule research compound with reported anti-fibrotic, antioxidant, and anti-inflammatory effects. Supplied as a purified analytical standard suitable for in vitro and in vivo studies and commonly provided as a 50 mg pack.
- Orally active small molecule with anti-fibrotic and anti-inflammatory activity.
- Demonstrated cellular effects (e.g., NIH/3T3 IC50 ~2.75 mM) and in vitro activity in lung and cancer cell lines.
- Shows protective effects in rodent models of lung injury, cholestasis, and fibrosis.
- High purity suitable for analytical and preclinical research applications.
- Molecular formula C12H10FNO; molecular weight 203.21 g/mol.
eMolecules 944904-85-2 | ChemScene | 1-(5-(Trifluoromethyl)pyridin-3-yl)ethanone | 100mg | 632294631 | CS-0155107 | MFCD10696266 | 189.137 | C8H6F3NO
ChemScene | 1-(5-(Trifluoromethyl)pyridin-3-yl)ethanone | 100mg | 632294631 | CS-0155107 | 944904-85-2 | MFCD10696266 | 189.137 | C8H6F3NO
Medchemexpress LLC PR5-LL-CM01 | 1005307-86-7 | 98.4% | 401.51 | 50 MG
PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC50 of 7.5 μM. It exhibits anti-tumor activities and demonstrates efficacy in inhibiting cancer cells while showing low toxicity in normal cells.
- Has IC50 values ranging from 2-4 μM in PDAC cells (PANC1, MiaPaCa2, and AsPC1) and 10-11 μM in CRC cells (HT29, HCT116, and DLD1).
- Strongly inhibits colony-forming ability in both PANC1 and HT29 cells.
- Inhibits NF-κB activation and its target gene expression in PDAC and CRC cells.
- Significantly decreases TNFα and IL8 expression in both PANC1 and HT29 cells (at 0-15 μM).
- Shows significant anti-tumor effects in PANC1 and HT29 xenografted mice in vivo (20 mg/kg; i.p.; 3 times per week) without visibly affecting their body weight.
Medchemexpress LLC 4-Feruloylquinic acid | 2613-86-7 | 5 MG
4-Feruloylquinic acid, with a purity of 99.41%, is a chemical compound that may serve as a potential biomarker for food products. This white to off-white solid has a molecular weight of 368.34 and the chemical formula C17H20O9. It is intended for research use only.
- Potential biomarker for food products
- High purity of 99.41%
- Molecular formula: C17H20O9
- Molecular weight: 368.34
- Appearance: White to off-white solid
- Classified under Phenylpropanoids, Simple Phenylpropanols, Phenols, and Monophenols
- Initial source from plants
- In vitro solubility in DMSO: 50 mg/mL (135.74 mM)
- Various in vivo dissolution protocols available
Medchemexpress LLC PF-4618433 | 1166393-85-6 | 98.62% | 445.52 | 100 MG
PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM. It may be suitable for the research of osteoporosis, craniofacial and appendicular skeletal defects, and for targeted bone regeneration.
- Potent and selective PYK2 inhibitor.
- IC50 of 637 nM against PYK2.
- Promotes osteogenesis of hMSC cultures.
- Increases alkaline phosphatase (ALP) activity and mineralization.
- Enhances osteoblast proliferation.
- Enhances calcium deposition.
- Molecular weight: 445.52.
- Formula: C24H27N7O2.
- Appearance: Solid, white to off-white.
- Storage: Powder at -20°C for 3 years, 4°C for 2 years; in solvent at -80°C for 6 months, -20°C for 1 month.
- Purity: 98.62%.
eMolecules 2757082-86-1 | Ambeed | (4R5R)-45-Diphenyl-2-(5-(trifluoromethyl)pyridin-2-yl)-45-dihydrooxazole | 100mg | 633418067 | A1349930 | 368.359 | C21H15F3N2O
Medchem Express | Antidepressant agent 1 | 5mg | 532149316 | HY-136171 | 67411-41-0 | 319.246 | C16H19BrN2
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Medchemexpress LLC Atuliflapon (AZD5718) | 2041075-86-7 | 99.0% | 50 MG
Atuliflapon (AZD5718) is a reversible inhibitor of 5-lipoxygenase activating protein (FLAP) developed for investigation of leukotriene-mediated inflammation and cardiovascular indications. It shows nanomolar potency against FLAP and has been evaluated in first-in-human and Phase 2a clinical studies. The compound is provided as a solid research sample for in vitro and translational research.
- Reversible FLAP inhibitor with FLAP IC50 ≈ 2 nM.
- Inhibits LTB4 production in human whole blood (IC50 ≈ 39 nM).
- High purity research sample (98.97%).
- Molecular weight 446.50 g/mol; chemical formula C24H26N6O3.
- Suitable for in vitro and translational/clinical research; not for clinical use.
- Pack size typically 50 mg solid sample.
Medchemexpress LLC N-cycloheptyl-6,7-dimethoxy-2-(4-piperidin-1-ylpiperidin-1-yl)quinazolin-4-amine | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 50 MG
C-021 is a small-molecule antagonist of CC chemokine receptor 4 (CCR4) developed for research applications; it blocks CCR4-mediated signaling and functional chemotaxis, with low-nanomolar activity in binding and cell-based assays.
- Potent CCR4 antagonist with low-nanomolar binding activity.
- Prevents CCL22-derived [35S]GTPγS binding to CCR4 (IC50 18 nM) and inhibits functional chemotaxis (human 140 nM, mouse 39 nM).
- Molecular formula C27H41N5O2; molecular weight 467.65 g/mol.
- High purity (~99.95%).
- Solid form with recommended storage: powder -20°C (long term) or 4°C (short term); in solvent store at -80°C.
- Intended for research use only; not for human use.
eMolecules 136381-85-6 | Medchem Express | Lintitript | 5mg | 506403383 | HY-101764 | MFCD00868618 | 411.86 | C20H14ClN3O3S
Ambeed | 14-Dimethyl-1H-indole-3-carbaldehyde | 250mg | 525880699 | A438363 | 170489-16-4 | MFCD11505328 | 173.215 | C11H11NO
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![Medchemexpress LLC 7-fluoro-6-methoxy-4-[6-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]quinol | 2248154-85-8 | MFCD32859311 | 99.4% | C26H30FN7O | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000260000.png-250.jpg)
Medchemexpress LLC 7-fluoro-6-methoxy-4-[6-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-3-yl]quinol | 2248154-85-8 | MFCD32859311 | 99.4% | C26H30FN7O | 10MG
KER047 (ALK2-IN-4) is a potent small-molecule inhibitor of activin receptor-like kinase-2 (ALK2) intended for research use in the study of ALK2-mediated signaling and metabolic disorders such as fibrodysplasia ossificans progressiva (FOP). The compound is provided in solid and solution formats for in vitro and preclinical investigations.
- Potent ALK2 inhibitor with demonstrated activity in research assays.
- Suitable for research into metabolic disease models, including FOP.
- High purity (99.4%) for reproducible experimental results.
- Available as solid powder and 10 mM solutions in DMSO for flexible dosing.
- Chemical formula C26H30FN7O and molecular weight 475.56 g/mol.
- Stable storage recommendations: powder at -20°C or 4°C; in solvent at -80°C or -20°C.
eMolecules 869185-85-3 | Medchem Express | Adezmapimod (hydrochloride) | 10mg | 446257795 | HY-10256A | MFCD01862622 | 413.9 | C21H17ClFN3OS
Medchem Express | Adezmapimod (hydrochloride) | 10mg | 446257795 | HY-10256A | 869185-85-3 | MFCD01862622 | 413.900 | C21H17ClFN3OS
Medchemexpress LLC 4-hydroxy-2-methyl-1,1-dioxo-N-(1,3-thiazol-2-yl)-1lambda6,2-benzothiazine-3-carboxamide | 34042-85-8 | MFCD00866053 | 95.0% | 337.37 g/mol | C13H11N3O4S2 | 5 MG
Sudoxicam is a reversible, orally active cyclooxygenase (COX) antagonist from the enol-carboxamide class of non-steroidal anti-inflammatory drugs (NSAIDs). Provided for laboratory research use only, it exhibits anti-inflammatory, anti-edema, and antipyretic activities and is supplied as a characterized solid for use in in vitro and in vivo pharmacology studies.
- Reversible COX antagonist with anti-inflammatory, anti-edema, and antipyretic activity.
- Enol-carboxamide class NSAID commonly used in pharmacology research.
- Supplied as a solid suitable for dissolution in common laboratory solvents, such as DMSO.
- Characterized molecular weight and formula support reproducible experimental design.
- Available in small research quantities appropriate for dose-response and in vivo studies.
- Intended for research use only; not for human or clinical use.