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Filtered Search Results
eMolecules 844470-86-6 | ChemScene | 1-(3-Fluorophenyl)propan-1-amine hydrochloride | 100mg | 712788533 | CS-0432862 | MFCD28126471 | 189.66 | C9H13ClFN
ChemScene | 1-(3-Fluorophenyl)propan-1-amine hydrochloride | 100mg | 712788533 | CS-0432862 | 844470-86-6 | MFCD28126471 | 189.660 | C9H13ClFN
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Medchemexpress LLC C-021 | 864289-85-0 | 100.0% | 467.65 g/mol | C27H41N5O2 | 25 MG
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C-021 is a small-molecule CCR4 antagonist supplied for research use. It inhibits CCR4-mediated chemotaxis in human and mouse cells and blocks CCL22-induced GTPγS binding, making it suitable for biochemical and cellular assays.
- Target: CCR4 (GPCR), suitable for immunology and GPCR research.
- Potent CCR4 antagonist with reported IC50s of 140 nM (human chemotaxis), 39 nM (mouse chemotaxis), and 18 nM in GTPγS binding assays.
- Molecular formula C27H41N5O2 and molecular weight 467.65 g/mol.
- Reported purity 99.95% and solid appearance (off-white to light yellow).
- Recommended storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human or animal therapeutic use.
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Medchemexpress LLC 2-(2,2,3,3,3-pentafluoropropoxy)-3-(4-(2,2,2-trifluoroethoxy)phenyl)-5,7-dihydropyrrolopyrimidine-4,6-dione | 1236767-85-3 | 99.9% | 473.27 | C17H11F8N3O4 | 100 MG
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D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor supplied as a powder for research use. It shows low-nanomolar potency (IC50 22 nM human, 72 nM rat), has molecular weight 473.27, and is reported at high purity (99.9%). Preclinical studies indicate improved insulin sensitivity and weight reduction in diet-induced obese mice. Store and handle per the manufacturer's recommendations.
- Selective delta-5 desaturase inhibitor with low-nanomolar potency.
- High purity suitable for pharmacology studies (99.9%).
- Powder form, convenient for formulation and dosing.
- Suitable for in vitro and in vivo pharmacology studies.
- Certificate of analysis and safety data sheet available.
- Defined storage conditions for powder and solutions to preserve stability.
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Medchemexpress LLC Regaloside C | 117591-85-2 | 5 MG
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Regaloside C is an anti-inflammatory agent and antioxidant that scavenges ABTS and DPPH free radicals. It targets multiple molecules including TNF-α, MMP-2, ERα, AKT1, TLR4, and HSP90-α, making it applicable to research related to inflammatory diseases.
- Acts as an anti-inflammatory agent.
- Acts as an antioxidant.
- Scavenges ABTS free radicals.
- Scavenges DPPH free radicals.
- Targets multiple molecules.
- Applicable to research related to inflammatory diseases.
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Medchemexpress LLC GPX4-IN-3 | 2761004-85-5 | 99.8% | C29H24ClN3O3S | 100 MG
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GPX4-IN-3 is a potent and selective glutathione peroxidase 4 (GPX4) inhibitor and a selective ferroptosis inducer. It demonstrates significant inhibition of GPX4 and effectively induces ferroptosis in various cell lines, showing a strong ability to increase lipid peroxides. This compound also exhibits antitumor activity and good biological safety in preclinical models, effectively suppressing tumor growth.
- Potent glutathione peroxidase 4 (GPX4) inhibitor
- Selective ferroptosis inducer
- Increases lipid peroxide levels
- Induces ferroptosis with satisfactory selectivity
- Increases reactive oxygen species (ROS) levels in 4T1 cells
- Exhibits antitumor activity
- Good biological safety in vivo
- Suppresses tumor growth in mouse xenograft models
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Medchemexpress LLC Benzenesulfonamide, N-[(4-bromophenyl)methyl]-4-chloro-N-[(3R)-hexahydro-2-oxo-1H-aze | 851600-86-7 | 99.5% | C19H20BrClN2O3S | 100 MG
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ELN318463 is an amyloid precursor protein (APP) selective γ-secretase inhibitor, demonstrating 51-fold selectivity for PS1 with EC50s of 12 nM for PS1 and 656 nM for PS2. It functions as a classic γ-secretase inhibitor, selectively inhibiting Aβ production over Notch signaling in cells. Oral administration *in vivo* leads to an acute reduction of brain Aβ in models of Alzheimer's disease.
- Amyloid precursor protein (APP) selective γ-secretase inhibitor
- Exhibits differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase
- Demonstrates 51-fold selectivity for PS1
- Selectively inhibits Aβ production over Notch signaling in cells
- Displaces an active site directed inhibitor *in vitro*
- Leads to acute reduction of brain Aβ *in vivo* in Alzheimer's disease models
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eMolecules 1005307-86-7 | Medchem Express | PR5-LL-CM01 | 5mg | 721309303 | HY-109963 | 401.518 | C23H27N7
Ambeed | N-(2-Bromo-5-fluorophenyl)acetamide | 25g | 714083594 | A1519939 | 1009-06-9 | MFCD09753710 | 232.052 | C8H7BrFNO
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Medchemexpress LLC (R)-5,7-Dimethoxyflavanone | 1277188-85-8 | MFCD31746978 | 1 MG
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(R)-5,7-Dimethoxyflavanone is a compound that demonstrates potent antimutagenic activity against MeIQ mutagenesis in Ames tests using S. typhimurium TA100 and TA98 strains. It also significantly and dose-dependently inhibits inflammatory mediators. This product is for research use only.
- Potent antimutagenic activity
- Inhibits inflammatory mediators
- Molecular weight: 284.31
- Formula: C17H16O4
- Appearance: solid
- Color: white to off-white
- Classified under flavonoids and flavanones
- Initial source from plants
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Medchemexpress LLC 4-hydroxy-2-methyl-1,1-dioxo-N-(1,3-thiazol-2-yl)-1λ6,2-benzothiazine-3-carboxamide | 34042-85-8 | MFCD00866053 | 100.0% | 337.37 g/mol | C13H11N3O4S2 | 100 MG
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Sudoxicam is an enol-carboxamide non-steroidal anti-inflammatory compound that functions as a reversible cyclooxygenase (COX) antagonist. It is provided as a high-purity analytical reagent intended for in-vitro and preclinical research use only (not for human or clinical use).
- Purity: 99.96%.
- CAS number: 34042-85-8.
- Molecular weight: 337.37 g/mol.
- Molecular formula: C13H11N3O4S2.
- Typical pack size: 100 mg solid.
- Intended use: research reagent and analytical standard for COX inhibition studies.
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eMolecules 20245-85-6 | ChemScene | 9-Ethenylpurin-6-amine (Adefovir Impurity) | 10mg | 642097385 | CS-0188802 | MFCD02185049 | 161.168 | C7H7N5
ChemScene | (1-Methyl-1236-tetrahydropyridin-4-yl)methanol | 100mg | 712788587 | CS-0433591 | 36166-75-3 | MFCD00023274 | 127.187 | C7H13NO
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eMolecules 82782-85-2 | Methyl 4H-thieno[3,2-b]pyrrole-5-carboxylate | Ambeed | MFCD06797484 | 181.210 | C8H7NO2S | 98.000 | COC(=O)c1cc2sccc2[nH]1 | 100mg | 490503631
Methyl 4H-thieno[3,2-b]pyrrole-5-carboxylate | Ambeed | 82782-85-2 | MFCD06797484 | 181.210 | C8H7NO2S | 98.000 | COC(=O)c1cc2sccc2[nH]1 | 100mg | 490503631
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eMolecules 114482-86-9 | Medchem Express | Oroxin B | 5mg | 489863287 | HY-N1435 | MFCD22125002 | 594.522 | C27H30O15
ChemScene | 6-Bromo-4-methoxypyrazolo[15-a]pyridine-3-carboxaldehyde | 50mg | 801475575 | CS-0040618 | 1207839-91-5 | MFCD28369514 | 255.071 | C9H7BrN2O2
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Medchemexpress LLC Atuliflapon (AZD5718) | 2041075-86-7 | 99.0% | 100 MG
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Atuliflapon (AZD5718) is a small-molecule, orally active inhibitor of 5-lipoxygenase activating protein (FLAP) investigated as a research compound for cardiovascular indications such as coronary artery disease. It potently suppresses leukotriene production and has documented preclinical and clinical pharmacology data.
- Oral FLAP inhibitor with potent activity (reported FLAP IC50 ≈ 2 nM).
- Reduces leukotriene production in human whole blood.
- Reported molecular weight 446.50 g·mol⁻¹ and formula C24H26N6O3.
- High purity (about 99.0%), white to off-white solid.
- Soluble in DMSO (≈125 mg/mL); sonication may be required for full dissolution.
- Powder storage: -20°C for long-term stability; in solvent, store at -80°C when possible.
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eMolecules 37924-85-9 | Ambeed | 3-(Bromomethyl)benzo[d]isoxazole | 100mg | 552734335 | A466071 | MFCD03701148 | 212.046 | C8H6BrNO
Ambeed | 4-(4455-Tetramethyl-132-dioxaborolan-2-yl)thiophene-2-carbaldehyde | 250mg | 525050946 | A141600 | 881381-12-0 | MFCD12756464 | 238.110 | C11H15BO3S
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Medchemexpress LLC Gpx4-in-3 | 2761004-85-5 | 99.8% | C29H24ClN3O3S | 50 MG
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Gpx4-in-3 | 2761004-85-5 | 99.8% | C29H24ClN3O3S | 50 MG
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