Azobenzenes
eMolecules 1452458-86-4 | Medchem Express | Nacubactam | 5mg | 628192271 | HY-109008 | 324.31 | C9H16N4O7S
Medchem Express | DSR-141562 | 5mg | 532149366 | HY-136569 | 2007975-22-4 | 414.429 | C19H25F3N4O3
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![eMolecules 126120-86-3 | 2,2-DIFLUOROBENZO[D][1,3]DIOXOL-4-OL | AstaTech | MFCD18451422 | 174.103 | C7H4F2O3 | 95.000 | Oc1cccc2OC(F)(F)Oc12 | 0.25g | 436051980](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502459679.PNG-250.jpg)
eMolecules 126120-86-3 | 2,2-DIFLUOROBENZO[D][1,3]DIOXOL-4-OL | AstaTech | MFCD18451422 | 174.103 | C7H4F2O3 | 95.000 | Oc1cccc2OC(F)(F)Oc12 | 0.25g | 436051980
2,2-DIFLUOROBENZO[D][1,3]DIOXOL-4-OL | AstaTech | 126120-86-3 | MFCD18451422 | 174.103 | C7H4F2O3 | 95.000 | Oc1cccc2OC(F)(F)Oc12 | 0.25g | 436051980
eMolecules 6750-85-2 | Ambeed | 5-(Methoxycarbonyl)furan-2-carboxylic acid | 100mg | 601095712 | A259026 | MFCD19441220 | 170.12 | C7H6O5
Ambeed | 5-(Methoxycarbonyl)furan-2-carboxylic acid | 100mg | 601095712 | A259026 | 6750-85-2 | MFCD19441220 | 170.120 | C7H6O5
Medchemexpress LLC PF-4618433 | 1166393-85-6 | 98.62% | 445.52 | 100 MG
PF-4618433 is a potent and selective PYK2 inhibitor, with an IC50 of 637 nM. It may be suitable for the research of osteoporosis, craniofacial and appendicular skeletal defects, and for targeted bone regeneration.
- Potent and selective PYK2 inhibitor.
- IC50 of 637 nM against PYK2.
- Promotes osteogenesis of hMSC cultures.
- Increases alkaline phosphatase (ALP) activity and mineralization.
- Enhances osteoblast proliferation.
- Enhances calcium deposition.
- Molecular weight: 445.52.
- Formula: C24H27N7O2.
- Appearance: Solid, white to off-white.
- Storage: Powder at -20°C for 3 years, 4°C for 2 years; in solvent at -80°C for 6 months, -20°C for 1 month.
- Purity: 98.62%.
Medchemexpress LLC Pegaptanib sodium | 222716-86-1 | 90.51% | 50000 (Approximately) | 500 MG
Pegaptanib sodium is an RNA aptamer with polyethylene glycol modifications, directed against vascular endothelial growth factor (VEGF)-165. It can be used for the study of neovascular age-related macular degeneration (AMD).
- Solid appearance.
- White to off-white color.
- Inhibits VEGF165-mediated phosphorylation of VEGFR2 and phospholipase Cγ.
- Inhibits VEGF165-induced calcium mobilization in human umbilical vein endothelial cells.
- Targets vascular endothelial growth factor-165.
- Suitable for the study of neovascular age-related macular degeneration.
![eMolecules 1558023-86-1 | Ambeed | Anthra[219-def6510-def]diisoquinoline-13810(2H9H)-tetrone 29-bis[3-(dimethyloxidoamino)propyl]- | 100mg | 633419517 | A1156199 | 592.652 | C34H32N4O6](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502452240.PNG-250.jpg)
eMolecules 1558023-86-1 | Ambeed | Anthra[219-def6510-def]diisoquinoline-13810(2H9H)-tetrone 29-bis[3-(dimethyloxidoamino)propyl]- | 100mg | 633419517 | A1156199 | 592.652 | C34H32N4O6
Medchem Express | 5-ROX | 5mg | 446274288 | HY-D0784 | 216699-35-3 | MFCD28355897 | 534.612 | C33H30N2O5
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Medchemexpress LLC GSK1702934A | 924377-85-5 | 99.11% | 395.52 | 10 MG
GSK1702934A is a selective agonist for TRPC3, a transient receptor potential canonical channel. It plays a role in modulating cardiac contractility and arrhythmogenesis through the activation of TRPC3. In vitro studies have shown its ability to induce TRPC3/6-currents in HEK293 cells, with EC50 values of 0.08 mM for TRPC3 and 0.44 mM for TRPC6. It also induces transient, non-selective conductance and prolonged action potentials in TRPC3-overexpressing myocytes, and promotes NCX currents. In vivo, GSK1702934A has been observed to transiently increase blood pressure in conscious Sprague Dawley rats at doses ranging from 0.3-3 mg/kg.
- Acts as a selective agonist for TRPC3.
- Modulates cardiac contractility and arrhythmogenesis by activating TRPC3.
- Induces TRPC3/6-currents in HEK293 cells.
- Promotes NCX currents in TRPC3-overexpressing myocytes.
- Increases blood pressure in vivo in animal models.
Medchemexpress LLC (R)-5,7-Dimethoxyflavanone | 1277188-85-8 | 5 MG
(R)-5,7-Dimethoxyflavanone exhibits potent antimutagenic activity against MeIQ mutagenesis in Ames test utilizing S. typhimurium TA100 and TA98 strains. Additionally, it significantly and dose-dependently inhibits inflammatory mediators.
- Potent antimutagenic activity
- Inhibits inflammatory mediators
- Molecular weight of 284.31
- Chemical formula C17H16O4
- Appears as a white to off-white solid
- Classified as a flavonoid and flavanone
- Initially sourced from plants
![eMolecules 434936-85-3 | IMIDAZO[1,2-A]PYRAZIN-8-OL | AstaTech | MFCD11846490 | 135.126 | C6H5N3O | 95.000 | Oc1nccn2ccnc12 | 0.25g | 268500354](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502455661.PNG-250.jpg)
eMolecules 434936-85-3 | IMIDAZO[1,2-A]PYRAZIN-8-OL | AstaTech | MFCD11846490 | 135.126 | C6H5N3O | 95.000 | Oc1nccn2ccnc12 | 0.25g | 268500354
IMIDAZO[1,2-A]PYRAZIN-8-OL | AstaTech | 434936-85-3 | MFCD11846490 | 135.126 | C6H5N3O | 95.000 | Oc1nccn2ccnc12 | 0.25g | 268500354
Medchemexpress LLC MIND4-19 | 129544-85-0 | 99.93% | 373.47 | 100 MG
MIND4-19 is a potent SIRT2 inhibitor with an IC50 value of 7.0 μM. MIND4-19 can be used for researching Huntington's disease.
- Potent SIRT2 inhibitor.
- IC50 value of 7.0 μM for SIRT2.
- Can be used for researching Huntington's disease.
eMolecules 1661845-86-8 | Medchem Express | CRT0105950 | 5mg | 784543803 | HY-120025 | 393.89 | C21H16ClN3OS
ChemScene | 23-Dichloro-6-nitroquinoxaline | 1g | 569146224 | CS-0105603 | 2379-60-4 | MFCD00454905 | 244.030 | C8H3Cl2N3O2
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Medchemexpress LLC Eln318463 | 851600-86-7 | 99.5% | 471.8 g/mol | C19H20BrClN2O3S | 10 MG
This compound is an amyloid precursor protein (APP)-selective γ-secretase inhibitor for in vitro research. It preferentially inhibits PS1-containing γ-secretase (EC50 = 12 nM) over PS2 (EC50 = 656 nM), providing ~51-fold selectivity. The solid is high purity, soluble in DMSO, and intended for biochemical and cellular assay applications.
- High purity (99.5%).
- APP-selective γ-secretase inhibitory activity.
- Potent PS1 inhibition (EC50 12 nM), reduced PS2 activity.
- Soluble in DMSO for assay preparation.
- Suitable for biochemical and cellular assays.
![eMolecules 86047-86-1 | 1,4-DIAZASPIRO[5.5]UNDECAN-5-ONE | AstaTech | MFCD07373481 | 168.240 | C9H16N2O | 95.000 | O=C1NCCNC11CCCCC1 | 1g | 718056409](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502465028.JPG-250.jpg)
eMolecules 86047-86-1 | 1,4-DIAZASPIRO[5.5]UNDECAN-5-ONE | AstaTech | MFCD07373481 | 168.240 | C9H16N2O | 95.000 | O=C1NCCNC11CCCCC1 | 1g | 718056409
1,4-DIAZASPIRO[5.5]UNDECAN-5-ONE | AstaTech | 86047-86-1 | MFCD07373481 | 168.240 | C9H16N2O | 95.000 | O=C1NCCNC11CCCCC1 | 1g | 718056409
Medchemexpress LLC Lupiwighteone | 104691-86-3 | 99.5% | 338.35 | C20H18O5 | 10 MG
Lupiwighteone is an isoflavone research compound used as a biochemical probe for studies of antioxidant, antimicrobial, and anticancer activity. It induces caspase-dependent and -independent apoptosis in cancer cells through inhibition of the PI3K/Akt/mTOR pathway. The material is supplied as a small solid suitable for preparation of DMSO stocks and in vivo formulation.
- Isoflavone small molecule for in vitro and in vivo research.
- Induces apoptosis via PI3K/Akt/mTOR pathway inhibition.
- Solubility: DMSO 100 mg/mL (in vitro); ≥2.5 mg/mL in 10% DMSO/90% corn oil (in vivo).
- Storage: store at 4°C, protect from light; in solvent -80°C (6 months) or -20°C (1 month).
- Key identifiers: CAS 104691-86-3; formula C20H18O5; molecular weight 338.35.