Benzimidazoles
Medchemexpress LLC Albendazole (Standard) | 54965-21-8 | 98.3% | 50 MG
Albendazole (Standard) is the analytical standard of Albendazole, intended for research and analytical applications. This orally active, broad-spectrum parasiticide is known for its high effectiveness and low host toxicity, and is utilized in the research of gastrointestinal parasites in both humans and animals.
- Induces apoptosis and autophagy in cancer cells.
- Inhibits tubulin polymerization.
- Inhibits HIF-1α and VEGF expression.
- Possesses antioxidant activity.
- Hinders the glycolytic process in cancer cells.
- Commonly used in qualitative, quantitative, and methodological research experiments, including techniques such as HPLC, GC, and MS.
- Serves as a reference standard for assays.
Apexbio Technology LLC Albendazole Oxide 54029-12-8 50mg
Albendazole Oxide (CAS 54029-12-8) is a small-molecule inhibitor targeting beta-tubulin It is designed to inhibit beta-tubulin polymerization in parasites thereby disrupting cytoplasmic microtubule structure and interfering with glucose metabolic pathways Albendazole Oxide exerts its biological activity primarily through inhibition of beta-tubulin polymerization In both in vitro and in vivo studies Albendazole Oxide demonstrates anti-parasitic activity with reported IC50 values typically ranging from nanomolar to micromolar concentrations depending on the parasite species and assay system Based on these pharmacological properties Albendazole Oxide holds research potential in the exploration of anti-parasitic pharmacodynamics notably for studies involving Echinococcus spp and other parasitic infections
Medchemexpress LLC Albendazole (Standard) (SKF-62979 (Standard)) | 54965-21-8 | 98.3% | 25 MG
Albendazole (Standard) is an analytical standard for research and analytical applications. This orally active, broad-spectrum parasiticide shows high effectiveness and low host toxicity, used for studying gastrointestinal parasites. It induces apoptosis and autophagy in cancer cells, inhibits tubulin polymerization, HIF-1α, and VEGF expression, and demonstrates antioxidant activity, inhibiting the glycolytic process in cancer cells.
- Analytical standard for research and analysis
- Orally active, broad-spectrum parasiticide
- High effectiveness and low host toxicity
- Used for research of gastrointestinal parasites
- Induces apoptosis and autophagy in cancer cells
- Inhibits tubulin polymerization, HIF-1α, and VEGF expression
- Exhibits antioxidant activity
- Inhibits glycolytic process in cancer cells
- Applied in HPLC, GC, and MS research experiments
Cayman Chemical Albendazole 50g
A benzimidazole anthelmintic; active against a variety of helminths, including liver flukes, tapeworms, and roundworms; eliminates Trichostrongylus in the fourth stomach of cattle and sheep (2.5-10 mg/kg) as well as other species; protects mice against lethal infection with A. suum larvae (0.05% in the diet); inhibits growth of HT-29 human colorectal cancer cells (IC50 = 0.12 µM), halts the cell cycle at the G2/M phase, and induces apoptosis; inhibits peritoneal tumor growth in an HT-29 mouse xenograft model (150 mg/kg, i.p.); inhibits mammalian tubulin polymerization and inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin (IC50s = 6.9 and 0.21 µM, respectively)
Selleck Chemical LLC Albendazole S1640-1g
Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations
Selleck Chemical LLC Albendazole Oxide S1836-50mg
Albendazole Oxide (Ricobendazole Albendazole sulfoxide) is a tubulin polymerization or assembly inhibitor used for the treatment of a variety of parasitic worm infestations
Selleck Chemical LLC Albendazole S1640-50mg
Albendazole is a member of the benzimidazole compounds used as a drug indicated for the treatment of a variety of worm infestations
Apexbio Technology LLC Albendazole Oxide 54029-12-8 10mM (in 1mL DMSO)
Albendazole Oxide (CAS 54029-12-8) is a small-molecule inhibitor targeting beta-tubulin It is designed to inhibit beta-tubulin polymerization in parasites thereby disrupting cytoplasmic microtubule structure and interfering with glucose metabolic pathways Albendazole Oxide exerts its biological activity primarily through inhibition of beta-tubulin polymerization In both in vitro and in vivo studies Albendazole Oxide demonstrates anti-parasitic activity with reported IC50 values typically ranging from nanomolar to micromolar concentrations depending on the parasite species and assay system Based on these pharmacological properties Albendazole Oxide holds research potential in the exploration of anti-parasitic pharmacodynamics notably for studies involving Echinococcus spp and other parasitic infections
Medchemexpress LLC Fenbendazole (Standard) | 43210-67-9 | 99.9% | 25 MG
Fenbendazole (Standard) is an analytical standard and orally active benzimidazole anthelmintic agent with a broad antiparasitic range. It functions as a microtubule destabilizing agent, binding to tubulin and disrupting microtubule equilibrium in helminthes. It also stabilizes HIF-1α, shows anti-proliferative activity, induces apoptosis, and causes cell-cycle arrest, with demonstrated antitumor activity in mice xenografted with wild-type p53.
- Analytical standard for research and analytical applications
- Orally active benzimidazole anthelmintic agent
- Broad antiparasitic range
- Microtubule destabilizing agent
- Disrupts tubulin microtubule equilibrium
- Stabilizes HIF-1α
- Exhibits anti-proliferative and antitumor activity
- Induces apoptosis and cell-cycle arrest
- Applied in qualitative, quantitative, and methodological research (HPLC, GC, MS)
Medchemexpress LLC Albendazole (standard) | 54965-21-8 | 98.3% | 100 MG
Albendazole (Standard) is the analytical standard of Albendazole, intended for research and analytical applications. Albendazole is an orally active and broad-spectrum parasiticide with high effectiveness and low host toxicity, used for the research of gastrointestinal parasites in humans and animals. This compound is a grade of analytical standard, commonly used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Induces apoptosis and autophagy in cancer cells
- Inhibits tubulin polymerization and HIF-1α, VEGF expression
- Possesses antioxidant activity
- Inhibits the glycolytic process in cancer cells