Benzoxazines
TARGETMOL CHEMICALS INC HELICHRYSETIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Helichrysetin has mild anti-HIV-1 PR activity. Helichrysetin has great potentials for development as an anticancer agent it has cytotoxic effect on four selected cancer cell lines A549 MCF-7 Ca Ski and HT-29. purity: 96%
TARGETMOL CHEMICALS INC PROCYANIDIN B1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Procyanidin B1 isolated from commonly eaten fruits binds to the TLR4/MD-2 complex and has anti-inflammatory activity. purity: 99%
TARGETMOL CHEMICALS INC SANGGENON C 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 1. Sanggenon C (Sanggenone C) inhibits tumor cellular proteasomal activity and cell viability via induction of cell cycle arrest and cell death inhibiting the proteasome function. 2. Sanggenon C and O inhibited NO production and iNOS expression by suppressing NF-(kappa)B activity and I(kappa)B(alpha) activation; inhibited TNF-alpha -stimulated PMN-HSC adhesion and expression of VCAM-1 by suppressing the activation of NF-kappaB. purity: 98%
TARGETMOL CHEMICALS INC PHA-665752 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PHA-665752 is an effective specific and ATP-competitive c-Met inhibitor (IC50 9 nM) >50-fold selectivity for c-Met than STKs or RTKs. purity: 99%
TARGETMOL CHEMICALS INC ZT-1A 5MG
Also available in 1 mg and bulk. Please contact Fisher for quotes. ZT-1a is a SPAK inhibitor.ZT-1a inhibits SPAK.ZT-1a can be used for the prevention and treatment of neurodegenerative and neurocognitive disorders. purity: 99%
Cell Signaling Technology GFAP E4L7M XPR Rabbit mAb
GFAP (E4L7M) XP(R) Rabbit mAb (Alexa Fluor(R) 647 Conjugate) 100 ul
TARGETMOL CHEMICALS INC EMD57033 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. EMD57033 is a cardiac troponin C (cTnC) activator a dominant Ca2+ sensitizer which functions by binding to cardiac/slow skeletal troponin C heterodimers to promote cardiac contraction. purity: 99%
TARGETMOL CHEMICALS INC DBET1 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50 430 nM) and induces apoptosis. purity: 99%
TARGETMOL CHEMICALS INC ALISOL B 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions. Alisol B also inhibited RANKL-induced expression of NFATc1 and c-Fos which are key transcription factors for osteoclastogenesis. purity: 99%
Cell Signaling Technology CD14 (D7A2T) Rabbit mAb (Alexa Fluor(R) 555 Conjugate) 100 ul
CD14 (D7A2T) Rabbit mAb (Alexa Fluor(R) 555 Conjugate) 100 ul
TARGETMOL CHEMICALS INC ERSO 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. ErSO is a selective activator of anticipatory unfolded protein response (UPR) via ER(alpha) receptor. ErSO can be used in studies about anti-cancer. purity: 98%
Cell Signaling Technology BATF D7C5 Rabbit mAb Alexa
BATF (D7C5) Rabbit mAb (Alexa Fluor(R) 647 Conjugate) 100 ul
TARGETMOL CHEMICALS INC ATC 0175 HYDROCHLORIDE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affinity for MCH1R MCH2R MCH1 5-HT2B receptors and 5-HT1A receptors with IC50s of 13.5 nM >10000 nM 13 nM 9.66 nM and 16.9 nM respectively. ATC 0175 hydrochloride exhibits antidepressant and anxiolytic effects in animal models. aTC 0175 can be used to study depression and/or anxiety disorders. purity: 99%
TARGETMOL CHEMICALS INC CALCIFEDIOL 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Calcifediol (U 32070E)(Ki of 3.9 uM) a major circulating metabolite of vitamin D3 works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA. purity: 99%