Benzoxazines
AdipoGen IDA
Chemical. CAS 163556-04-5. Formula C12H9NO4. MW 231.2. Synthetic. Amino compounds having primary groups such as amino acids or aminocyclitol antibiotics lack chromopores or fluorophores in their molecules. Derivatization is required for their detection with high sensitivity using high-performance liquid chromatography or high-performance apillary electrophoresis with photometric and fluorimetric detection. Reagent for the derivatisation of primary amines. The alanine-derivative shows a 3 times stronger fluorescence than o-phthalaldehyde. The reagent has been used in the HPCE-determination of aminoacids.
AdipoGen Me-Umbelliferyl-maleinimide
Chemical. CAS 211565-47-8. Formula C14H9NO4. MW 255.23. Synthetic. Fluorescent reagent with high selectivity.
AdipoGen 7-MeO-coumarin-3-carbonyl azid
Chemical. CAS 97632-67-2. Formula C11H7N3O4. MW 220.18. Synthetic. Fluorescent reagent.
TARGETMOL CHEMICALS INC GSK180736A 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GSK180736A is an effective and selective GRK2 inhibitor (IC50 0.77 uM) and >100-fold selectivity over other GRKs. It is a weak inhibitor of PKA (IC50 30 uM) but highly effective against ROCK1 (IC50 100 nM). purity: 98%
TARGETMOL CHEMICALS INC IDE1 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50 125.5 nM in vitro) by activating the TGF-(beta) signaling pathway. IDE1-derived endodermal cells injected into E8.75 mouse embryos ex vivo have been shown to incorporate into the developing gut tube contributing to its formation. purity: 98%
TARGETMOL CHEMICALS INC HUHS015 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. HUHS015 is a potent PCA-1/ALKBH3 inhibitor. purity: 99%
TARGETMOL CHEMICALS INC SCH-900271 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SCH-900271 is a potent nicotinic acid receptor for the treatment of dyslipidaemia and is commonly used in the study of mixed hyperlipidaemia and primary hypercholesterolaemia. purity: 98%
TARGETMOL CHEMICALS INC RU 47213 5MG
Also available in 1 mg 10 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. RU 47213 can be used to inhibit scopolamine-induced working memory impairment in rats. purity: 99%
TARGETMOL CHEMICALS INC CILIOBREVIN A 25MG
Also available in 2 mg 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Ciliobrevin A (HPI-4) is an inhibitor of hedgehog signaling pathway with an IC50 <10 uM. purity: 99%
TARGETMOL CHEMICALS INC S107 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. S107 is a RyR-selective 1 4-benzothiazepine derivative that stabilizes RyR2 channels by enhancing the binding affinity of calstabin2 to mutant and/or PKA-phosphorylated channels. purity: 99%
TARGETMOL CHEMICALS INC ELDACIMIBE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg and bulk. Please contact Fisher for quotes. Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders study of atherosclerosis and hypercholesterolemia. purity: 98%
TARGETMOL CHEMICALS INC ALVELESTAT 25MG
Also available in 1 mg 2 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Alvelestat (AZD9668) is an orally bioavailable selective and reversible inhibitor of human neutrophil elastase (NE) with potential anti-inflammatory activity. purity: 99%
TARGETMOL CHEMICALS INC NQDI-1 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1 MAP3K5) (IC50/Ki 3 uM/500 nM). purity: 97%
TARGETMOL CHEMICALS INC MOMIPP 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. MOMIPP is a PIKfyve inhibitor and a macropinocytosis inducer. MOMIPP readily penetrates the blood-brain barrier and is moderately effective in suppressing progression of intracerebral glioblastoma xenografts[1][2]. purity: 99%
TARGETMOL CHEMICALS INC MERODANTOIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Merodantoin is an apoptosis inducer and triggers cell apoptosis associated with ROS-dependent autophagy. Merodantoin targets cancer cells expressing KRAS mutations involved in Akt-dependent ROS production. purity: 100%