Benzoxazines
TARGETMOL CHEMICALS INC JACEOSIDIN 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity modulates the ERK/ATM/Chk1/2 pathway leading to inactivation of the Cdc2-cyclin B1 complex followed by G2/M cell cycle arrest in endometrial cancer cells. Jaceosidin has immunosuppressive effect through inhibiting T cell proliferation and activation which is closely associated with its potent down-regulation of the IFN-(gamma)/STAT1/T-bet signaling pathway. The pharmacokinetics of Jaceosidin may be dramatically affected by polymorphic CYP1A2 UGT1A1 and UGT1A7 responsible for the metabolism of Jaceosidin or by the coadministration of relevant CYP1A2 or UGT inhibitors or inducers. purity: 99%
![Amsbio LLC Fibronectin (FN1) (pFn) Mouse Monoclonal Antibody [Clone ID: BF12]](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502566455.png-250.jpg)
Amsbio LLC Fibronectin (FN1) (pFn) Mouse Monoclonal Antibody [Clone ID: BF12]
Fibronectin (FN1) (pFn) Mouse Monoclonal Antibody [Clone ID: BF12]
TARGETMOL CHEMICALS INC MIRANSERTIB 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Miransertib (ARQ-092) is an orally bioavailable selective and potent allosteric Akt inhibitor. purity: 99%
Aat Bioquest 5TRITC Tetramethylrhodamine
5TRITC [Tetramethylrhodamine5isothiocyanate] *CAS 80724192*
Abcam Resorufin, 20MG
MW 213.19 Da. Stable red fluorophore probe. Widely used in cell labeling and Amplex Red type enzyme assays. It represents the reduced dye formed from Amplex Red reaction or resazurin reductions. Unstable in the presence of thiols such as dithiothreitol (DTT) and 2-mercaptoethanol.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Oxazine 1 perchlorate | 24796-94-9 | MFCD00041971 | 97.0% | 423.89 g·mol⁻¹ | C20H26ClN3O5 | 10 MG
Oxazine 1 perchlorate is a symmetric cationic fluorescent dye that absorbs near 653 nm and emits at about 666 nm. It is used for red-region fluorescence labeling and detection in research applications and is supplied as a solid.
- Excitation at 653 nm and emission at 666 nm.
- Molecular formula C20H26ClN3O5; molecular weight 423.89 g·mol⁻¹.
- Typical purity about 97%.
- Available in small-mass packs suitable for research use.
- For research use only; not for clinical use or sale to patients.
Medchemexpress LLC Gallocyanine chloride | 1562-85-2 | 92.0% | 5 MG
Gallocyanine chloride is a synthetic blue dyestuff used in research for Alzheimer's disease and related neurodegenerative tauopathies. It inhibits DKK1/LRP6 interaction and activates the Wnt signaling pathway.
- Activates the Wnt signaling pathway
- Causes β-catenin accumulation
- Exhibits anti-metastasis, anti-inflammatory, and anti-fibrosis activities
- Can serve as a fluorescent probe for detecting superoxide anion radicals
eMolecules 486437-59-6 | 4-(4-Methylpiperidinyl)benzylamine | Oakwood Chemical | MFCD04971042 | 204.317 | C13H20N2 | 97.000 | CC1CCN(CC1)c1ccc(CN)cc1 | 1g | 537701512
4-(4-Methylpiperidinyl)benzylamine | Oakwood Chemical | 486437-59-6 | MFCD04971042 | 204.317 | C13H20N2 | 97.000 | CC1CCN(CC1)c1ccc(CN)cc1 | 1g | 537701512
Medchemexpress LLC Cinnabarinic acid | 606-59-7 | 99.9% | 300.22 | 10 MG
Cinnabarinic acid is identified as a specific orthosteric agonist of mGlu4, acting through interaction with residues in the glutamate binding pocket without activity at other mGlu receptors. It is an endogenous metabolite of the kynurenine pathway of tryptophan and is known to induce cell apoptosis.
- Specific orthosteric agonist of mGlu4.
- Acts via interaction with residues in the glutamate binding pocket of mGlu4.
- Shows no activity at other mGlu receptors (mGlu1, mGlu2, mGlu5, mGlu6, mGlu7, mGlu8).
- Endogenous metabolite of the kynurenine pathway of tryptophan.
- Induces cell apoptosis.
- Acts as a partial agonist of mGlu4 receptors.
- Increases [3H]InsP formation by approximately 35% at 100 μM.
- Reduces cAMP formation in a concentration-dependent manner.
- Effective at 30 μM in inhibiting cAMP formation in cultured cerebellar granule cells.
Cayman Chemical ResorufIn Acetate 25mg
A fluorometric probe that acts as a substrate for ALDH1A1 esterase activity and chymotrypsin
Cayman Chemical ResorufIn benzyl ether 1mg
A fluorometric probe that acts as a substrate for CYP3A4; typically used near its apparent Km value of 30 µM to screen the inhibition/activation potential of test compounds and to predict potential drug-drug interactions
TARGETMOL CHEMICALS INC 7-Ethoxyresorufin 10MG
Also available in 1 mg, 2 mg, 5 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. 7-Ethoxyresorufin (Resorufin ethyl ether) (7-ER) is a fluorometric substrate and competitive inhibitor of cytochrome P450, particularly CYP1A1. Purity 99.35%