Biotin and derivatives

Medchemexpress LLC M-PEG-NHS ester (MW 10000) | 92451-01-9 | 98.0% | Poly(oxy-1,2-ethanediyl), α-[2-[(2,5-dioxo-1-pyrrolidinyl)oxy]-2-oxoethyl]-ω-methoxy- | 25 MG

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m-PEG-NHS ester (MW 10000) is a PEG-based PROTAC linker. It is for research use only and not sold to patients. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. These compounds contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.

• Used in the synthesis of PROTACs
• Exploits the intracellular ubiquitin-proteasome system
• Selectively degrades target proteins
• Composed of PEG, alkyl, and ether groups

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eMolecules​ 1688598-83-5 | NHS-PEG1-SS-PEG1-NHS | Medchem Express436.410 | C14H16N2O10S2 | 98.000 | O=C(OCCSSCCOC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 100mg | 816503954

NHS-PEG1-SS-PEG1-NHS | Medchem Express | 1688598-83-5436.410 | C14H16N2O10S2 | 98.000 | O=C(OCCSSCCOC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 100mg | 816503954

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eMolecules​ 1807518-72-4 | Mal-PEG1-NHS ester | Medchem Express | MFCD26127783 | 310.262 | C13H14N2O7 | 98.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 10mg | 795391586

Mal-PEG1-NHS ester | Medchem Express | 1807518-72-4 | MFCD26127783 | 310.262 | C13H14N2O7 | 98.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 10mg | 795391586

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eMolecules​ 1807518-72-4 | Mal-PEG1-NHS ester | Broadpharm | MFCD26127783 | 310.262 | C13H14N2O7 | 0.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 500mg | 311074500

Mal-PEG1-NHS ester | Broadpharm | 1807518-72-4 | MFCD26127783 | 310.262 | C13H14N2O7 | 0.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 500mg | 311074500

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eMolecules​ 174569-25-6 | m-PEG12-NHS ester | Broadpharm | MFCD13184970 | 685.761 | C30H55NO16 | 95.000 | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 200622526

m-PEG12-NHS ester | Broadpharm | 174569-25-6 | MFCD13184970 | 685.761 | C30H55NO16 | 95.000 | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 200622526

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eMolecules​ 1807518-72-4 | Mal-PEG1-NHS ester | Medchem Express | MFCD26127783 | 310.262 | C13H14N2O7 | 98.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 250mg | 527575115

Mal-PEG1-NHS ester | Medchem Express | 1807518-72-4 | MFCD26127783 | 310.262 | C13H14N2O7 | 98.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 250mg | 527575115

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Medchemexpress LLC Bis-SS-C3-NHS ester | 98604-88-7 | 98.0% | 432.47 | C16H20N2O8S2 | 1 G

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Bis-SS-C3-NHS ester is a disulfide-cleavable N-hydroxysuccinimide (NHS) ester linker used for bioconjugation and antibody-drug conjugate (ADC) synthesis. It couples to primary amines via NHS-ester chemistry and releases payloads under reducing intracellular conditions.

• Molecular weight: 432.47
• Chemical formula: C16H20N2O8S2
• Cas number: 98604-88-7
• Purity: 98.0%
• Appearance: white to off-white solid
• Reactive group: NHS ester for coupling to primary amines
• Application: cleavable disulfide linker for ADC synthesis and bioconjugation
• Available pack size: 1 g

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Medchemexpress LLC Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 trifluoroacetate | 00-00-0 | 98.0% | C38H66F3N13O11S | 10MG

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Biotin-C1-PEG3-C3-amido-C5-Gly-Arg-Gly-N3 trifluoroacetate is an azide-containing biotinylated reagent for click chemistry labeling of proteins. It participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted alkyne-azide cycloaddition (SPAAC) to conjugate with alkyne-bearing probes, enabling detection of protein modification sites. Intended for research use.

• Contains an azide group for CuAAC and SPAAC reactions.
• Biotin tag enables affinity detection and signal amplification.
• PEG3 linker provides hydrophilicity and spacer flexibility.
• High purity (98.0%) suitable for labeling applications.
• White to off-white solid with recommended handling precautions.
• Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
• Store sealed at -20°C; in solvent store at -80°C for long-term stability.

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Medchemexpress LLC Bis-PEG9-NHS ester 1g | 1008402-79-6 | 1 G

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Bis-PEG9-NHS ester is a homobifunctional polyethylene glycol (PEG) linker bearing two N-hydroxysuccinimide (NHS) ester groups. It reacts with primary amines to form stable amide bonds and is used for protein conjugation, PROTAC and antibody-drug conjugate (ADC) linker synthesis. Provided as a high-purity research reagent.

• Homobifunctional PEG9 spacer with two NHS ester reactive groups.
• Enables amine-targeted conjugation to proteins and small molecules.
• PEG spacer increases aqueous solubility and reduces aggregation.
• Suitable for PROTAC and ADC linker synthesis and general bioconjugation.
• High purity for consistent research results.

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Ambeed AMBEED

5000949906 DBCO-BIOTIN 25MG

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eMolecules​ 58-85-5 | D-Biotin | Chemodex Ltd. | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 482921470

D-Biotin | Chemodex Ltd. | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 5g | 482921470

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Medchemexpress LLC Biotin-PEG-Biotin | 194920-55-3 | 99.3% | C26H44N6O6S2 | 50 MG

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Biotin-PEG-Biotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

• PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Exploits ubiquitin-proteasome system to degrade target proteins

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eMolecules​ 55750-61-3 | A-MALEIMIDOACETIC ACID-NHS(AMAS) | AstaTech | MFCD00133523 | 252.182 | C10H8N2O6 | 97.000 | O=C(CN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 25g | 881785810

A-MALEIMIDOACETIC ACID-NHS(AMAS) | AstaTech | 55750-61-3 | MFCD00133523 | 252.182 | C10H8N2O6 | 97.000 | O=C(CN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 25g | 881785810

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Medchemexpress LLC Biotin-Gastrin Releasing Peptide, human TFA | 3085.67 | 10 MG

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Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties.

• Molecular weight: 3085.67
• Chemical formula: C140H218N40O33S3.xC2HF3O2
• Appearance: Solid
• Soluble in DMSO at 100 mg/mL
• Shipping: Room temperature
• Storage (powder): -80°C for 2 years, -20°C for 1 year
• Storage (in solvent): -80°C for 6 months, -20°C for 1 month

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Medchemexpress LLC DBCO-NHS ester 2 1g | 1384870-47-6 | 1 G

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DBCO-NHS ester 2 is a dibenzoazacyclooctyne (DBCO)-containing N-hydroxysuccinimide (NHS) ester reagent for strain-promoted alkyne-azide cycloaddition (SPAAC). It is used to install a DBCO handle on amine-containing molecules for copper-free click conjugation to azide-functionalized partners and as a cleavable linker in bioconjugation workflows.

• Amine-reactive NHS ester for efficient coupling to primary amines.
• DBCO group enables strain-promoted copper-free click chemistry with azides.
• Suitable for bioconjugation and linker formation in antibody-drug conjugates.
• High reported purity for reproducible conjugation performance.
• Supplied as a 1 g quantity for small-scale synthesis and labeling.

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