Biotin and derivatives
Medchemexpress LLC Azido-PEG3-SS-NHS | 95.0% | 436.50 | C15H24N4O7S2 | 5 MG
Azido-PEG3-SS-NHS is a cleavable three-unit polyethylene glycol (PEG) linker intended for bioconjugation and antibody-drug conjugate synthesis. It contains an azide for click chemistry, a disulfide bond for reductive cleavage, and an N-hydroxysuccinimide (NHS) ester for amine coupling.
- Contains azide for copper-catalyzed and strain-promoted click reactions.
- Contains NHS ester for efficient conjugation to primary amines.
- Includes a cleavable disulfide spacer for intracellular release.
- Suitable for linker design in ADC, PROTAC, and other bioconjugation workflows.
- Supplied as a liquid, colorless to light yellow, with reported purity of 95.0%.
Medchemexpress LLC DBCO-NHS ester | 1353016-71-3 | 99.5% | 402.40 | C23H18N2O5 | 10 MG
DBCO-NHS ester is a dibenzocyclooctyne N-hydroxysuccinimidyl ester used as a click-chemistry linker to enable strain-promoted alkyne-azide cycloaddition (SPAAC) for bioconjugation and antibody-drug conjugate synthesis. Supplied as a powder with recommended storage and handling guidance; suitable for laboratory research applications.
- Click-chemistry reagent for strain-promoted alkyne-azide cycloaddition (SPAAC).
- High purity (≈99.5% by LCMS).
- Molecular weight 402.40, chemical formula C23H18N2O5.
- Available in small-mg packages for research use.
- Store as powder at -20°C; follow SDS for solution storage and handling.
Medchemexpress LLC Biotin methyl ester 1g
Biotin methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC DOTA-NHS-ester | 170908-81-3 | MFCD23381190 | >97.0% | 501.49 | C20H31N5O10 | 500 MG
DOTA-NHS-ester is a bifunctional chelator containing a DOTA macrocycle and an N-hydroxysuccinimide (NHS) ester. It enables covalent conjugation to amine-containing biomolecules and subsequent radiometal chelation for imaging or radiotherapy research applications.
- Bifunctional chelator with NHS-ester for amine conjugation.
- High purity (≥97.0%) solid suitable for research.
- Molecular weight 501.49 and formula C20H31N5O10.
- Soluble in DMSO (50 mg/mL) and compatible with common in vivo formulations.
- Store powder at -20°C; solutions at -80°C (6 months) or -20°C (1 month).
- Available in a 500 mg pack size.
Gold Biotechnology Inc D Biotin 5 g
Biotin can be used in cell culture media for its involvement in a number of cellular processes including gluconeogenesis synthesis of fatty acids and amino acids isoleucine and valine
Apexbio Technology LLC DOTA-NHS-ESTER-100MG
DOTA-NHS-ester (CAS No 170908-81-3) is widely utilized in biomedical research primarily for its role as a bifunctional chelating agent used in radiolabeling and conjugation processes Originating from the conjugation of DOTA (a macrocyclic chelator) with N-hydroxysuccinimide (NHS) this compound facilitates the attachment of radioactive metals to biomolecules enhancing imaging and therapeutic applications It operates by forming stable complexes with metal ions targeting specific pathways for precise diagnostic or therapeutic delivery In vitro activities typically exhibit a nanomolar to low micromolar range making it suitable for various applications such as drug screening cell labeling and receptor targeting in oncology research Its use extends to both cell models and animal studies allowing for robust experimental analysis Experimental concentrations typically depend on the specific research design ensuring versatility across different scientific investigations
Medchemexpress LLC Aeide-C1-NHS ester | 824426-32-6 | 98.0% | C6H6N4O4 | 100 MG
Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It is also capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Alkyl/ether-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Click chemistry reagent.
- Contains an Azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Medchemexpress LLC Biotin-PEG3-iodoacetamide | 2306161-26-0 | 97.0% | 586.48 | 100 MG
Biotin-PEG3-Iodoacetamide is a PEG derivative consisting of Biotin, 3 PEG units, and Iodoacetamide. Biotin forms a stable non-covalent bond with streptavidin, making this compound suitable for biochemical assays.
- Composed of Biotin, 3 PEG units, and Iodoacetamide
- Forms a stable non-covalent bond with streptavidin
- Suitable for biochemical assay reagents
- Soluble in DMSO: 100 mg/mL (ultrasonic)
- Purity: 97.0%
Medchemexpress LLC Azido-PEG1-NHS ester | 1807530-06-8 | 99.78% | C9H12N4O5 | 25 MG
Azido-PEG1-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It serves as a click chemistry reagent, containing an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs themselves are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an Azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Exploits the intracellular ubiquitin-proteasome system
- Selective degradation of target proteins
Sigma Aldrich Fine Chemicals Biosciences Biotin meets USP testing specifications | 58-85-5 | MFCD00005541 | 5G
Biotin meets USP testing specifications | Purity: 97.5-102.0% | Mol Wt: 244.31 | 58-85-5 | MFCD00005541 | 5G
Apexbio Technology LLC Sulfo-NHS-LC-Biotin, 100mg. Cas: 127062-22-0 MFCD: MFCD00078534. Amine-reactive biotinylation reagent, long chain
Intermediate length, water-soluble biotinyltation reagent used to attach biotin to primary amines 127062-22-0. MFCD00078534
Sigma Aldrich Fine Chemicals Biosciences Biotin powder, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, >=99% | 58-85-5 | MFCD00005541 | 5G
Biotin powder, BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture, >=99% | Purity: >=99% | Mol Wt: 244.31 | 58-85-5 | MFCD00005541 | 5G
Sigma Aldrich Fine Chemicals Biosciences Biotin | 58-85-5 | MFCD00005541 | 5 g
Biotin | Purity: 99% | Mol Wt: 244.31 | 58-85-5 | MFCD00005541 | 5 g