Biotin and derivatives
Gold Biotechnology Inc D Biotin 5 g
Biotin can be used in cell culture media for its involvement in a number of cellular processes including gluconeogenesis synthesis of fatty acids and amino acids isoleucine and valine
Medchemexpress LLC Azido-PEG3-O-NHS ester | 2110448-98-9 | 95% | C13H20N4O8 | 100 MG
Azido-PEG3-O-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This click chemistry reagent features an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN group-containing molecules.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
Medchemexpress LLC Azido-PEG10-NHS ester | 2801772-86-9 | 98.0% | C27H48N4O14 | 100 MG
Azido-PEG10-NHS ester is a versatile PEG-based PROTAC linker and click chemistry reagent. It contains an Azide group, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This compound is instrumental in the synthesis of PROTACs, which leverage the intracellular ubiquitin-proteasome system for targeted protein degradation.
- Functions as a PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Acts as a click chemistry reagent
- Contains an Azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Allows reactions with alkyne-containing molecules
- Supports strain-promoted alkyne-azide cycloaddition (SPAAC)
- Reacts with molecules containing DBCO or BCN groups
- Aids in selective degradation of target proteins
Medchemexpress LLC Propanoic acid, 3-(2-azidoethoxy)-, 2,5-dioxo-1-pyrrolidinyl ester | 1807530-06-8 | 99.8% | C9H12N4O5 | 50 MG
Azido-PEG1-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc)
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Suitable for use with molecules containing alkyne, DBCO, or BCN groups
- Enables selective degradation of target proteins
Medchemexpress LLC Azido-PEG12-NHS ester | 2363756-50-5 | 98.0% | C31H56N4O16 | 50 MG
Azido-PEG12-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules possessing Alkyne groups. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules
- Can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups
Medchemexpress LLC ATRA-biotin | 2226143-93-5 | >98.43% | C36H55N3O4S | 50 MG
ATRA-biotin, also known as Biotin-ATRA-conjugate, is a biotin-conjugated derivative of All-Trans Retinoic Acid (ATRA). This compound serves as a valuable tool for tracking ATRA within cellular environments or specific tissues, enabling researchers to investigate its distribution and interactions.
- Biotin-conjugated derivative of All-Trans Retinoic Acid (ATRA)
- Used to track ATRA in cells or a given tissue
- Targets RAR/RXR, PPAR, Endogenous Metabolite, and Autophagy pathways
- Soluble in DMSO at 100 mg/mL
- Demonstrates biocompatibility in cell viability assays
Medchemexpress LLC Sulfo-NHS-Acetate | 152305-87-8 | 98.0% | C6H7NO7S | 100 MG
Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs. It is intended for research use only.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
Medchemexpress LLC Biotin-PEG3-Mal | 1431618-70-0 | 98.9% | C25H39N5O8S | 50 MG
Biotin-PEG3-Mal is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Biotin-labeled
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Biotin-PEG6-Mal | 1808990-66-0 | 99.0% | C31H51N5O11S | 100 MG
Biotin-PEG6-Mal is a biotin-labeled, PEG-based PROTAC linker. It is used in the synthesis of PROTACs, which are molecules designed to exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs function by connecting two different ligands: one for an E3 ubiquitin ligase and another for the target protein. This product is for research use only.
- Biotin-labeled
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC 3-Pyrrolidinesulfonic acid, 1-(acetyloxy)-2,5-dioxo- | 152305-87-8 | 98.0% | C6H7NO7S | 25 MG
Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs are compounds containing two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Targets an E3 ubiquitin ligase
- Targets a specific protein
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
- Relevant to cancer research
- Relevant to cancer targeted therapy
- Classified as a PROTAC linker
- Functions as an inhibitor
Medchemexpress LLC Biotin-PEG8-acid | 2143964-62-7 | 99.8% | C29H53N3O12S | 100 MG
Biotin-PEG8-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Biotin-labeled, PEG-based PROTAC linker
- Can be used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Aeide-C1-NHS ester | 824426-32-6 | 98.0% | C6H6N4O4 | 100 MG
Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It is also capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Alkyl/ether-based PROTAC linker.
- Used in the synthesis of PROTACs.
- Click chemistry reagent.
- Contains an Azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups.
- PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.