Biotin and derivatives
Medchemexpress LLC Biotin-TAT (47-57) | 1231898-25-1 | 98.6% | 1786.12 | 10 MG
Biotin-TAT (47-57) is a biotin-tagged transactivator of transcription, identified as one of the most widely used protein transduction domains (PTDs). Its entry into various primary cells is ATP- and temperature-dependent, suggesting the involvement of endocytosis.
- Biotin-tagged
- Functions as a transactivator of transcription
- Acts as a widely used protein transduction domain (PTD)
- Entry into primary cells via an ATP- and temperature-dependent mechanism
- Involvement of endocytosis in cellular uptake
- Useful in peptide and derivatives research
- Applicable in peptide for drug delivery
- Functions as a cell-penetrating peptide
- Identified as a fluorescent dye
Medchemexpress LLC Biotin-X-NTA | 856661-92-2 | 98.1% | 715.98 | 5 MG
Biotin-X-NTA is a reagent used for detecting histidine-tagged proteins immobilized on nitrocellulose membranes.
- Fluorescent dye
- Labeling chemistry reagent
- Functional group type biotin dye
- Detects histidine-tagged proteins
- Suitable for nitrocellulose membranes
Medchemexpress LLC m-PEG1-NHS ester 250mg | 1027371-75-0 | 201.18 g/mol | C8H11NO5 | 250 MG
m-PEG1-NHS ester is a PEG/alkyl/ether-based N-hydroxysuccinimide (NHS) ester linker used for assembling proteolysis targeting chimeras (PROTACs) and for amine-directed bioconjugation. Supplied as a solid, it provides a short PEG spacer with an activated ester for efficient coupling in synthetic workflows.
- PEG/alkyl/ether-based linker for PROTAC synthesis.
- N-hydroxysuccinimide ester reactive toward primary amines.
- Molecular weight 201.18 g/mol.
- Chemical formula C8H11NO5.
- Purity 95.0%.
- Appearance white to light yellow solid.
- Storage: powder -20°C (3 years); in solvent -80°C (6 months), -20°C (1 month).
- Available package size 250 MG.
eMolecules Z-Gly-ONp | 1738-86-9 | MFCD00024663 | 1g
Combi-Blocks | Z-Gly-ONp | 1g | 335350486 | QB-6326 | 97.000 | 1738-86-9 | MFCD00024663 | 330.296 | C16H14N2O6
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool
Medchemexpress LLC Biotin-C5-Azide (DecarboxyBiotin-N3) | 1260586-88-6 | C10H17N5OS | 1 ML
Biotin-C5-Azide (DecarboxyBiotin-N3) is a biotin reagent used to prepare biotinylated conjugates. It functions as a click chemistry reagent, containing an Azide group that allows it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Used to prepare biotinylated conjugates
- Functions as a click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
Medchemexpress LLC Bis-PEG30-NHS ester | 1633.81 | 25 MG
Bis-PEG30-NHS ester is a non-cleavable 30-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
- Target: ADC linker
- Pathway: Antibody-drug conjugate/ADC related
![Medchemexpress LLC Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | MFCD00083163 | 98.1% | 425.52 | C18H23N3O5S2 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000235572.png-250.jpg)
Medchemexpress LLC Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | MFCD00083163 | 98.1% | 425.52 | C18H23N3O5S2 | 100MG
SPDP-C6-NHS ester is a heterobifunctional alkyl/ether-based linker bearing an N-hydroxysuccinimide (NHS) ester and a pyridyldithiol moiety, designed for bioconjugation and assembly of bifunctional molecules such as PROTACs. The NHS ester enables amine coupling to form stable amide bonds, while the pyridyldithiol group allows disulfide formation with thiols, providing modular chemistry for linking ligands, payloads, or proteins.
Medchemexpress LLC Biotin-Oxytocin | 99.9% | 1233.48 | 1 MG
Biotin-Oxytocin is a biologically active peptide. It is Oxytocin that has been N-terminally labeled with Biotin.
- Biological active peptide.
- N-terminally labeled.
Medchemexpress LLC Pentanediamide, N1-[4-[[4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo... | 1599432-18-4 | MFCD30496724 | 99.7% | 1097.37 g/mol | C56H80N12O9S | 50 MG
Ibrutinib-biotin is a biotin-conjugated chemical probe derived from the BTK inhibitor ibrutinib. It features ibrutinib linked to biotin via a long-chain linker and is designed for target engagement, affinity pull-downs, and assay development directed at Bruton's tyrosine kinase (BTK).
- Biotin-conjugated probe for affinity capture and pull-down assays.
- Derived from a BTK inhibitor for target-specific engagement.
- Low-nanomolar potency against BTK (IC50 0.755-1.02 nM).
- High purity suitable for research applications (>99.6%).
- Available as solid material and as a 10 mM solution in DMSO.
- Molecular weight approximately 1,097.37 g/mol.
Medchemexpress LLC Ibrutinib-biotin | 1599432-18-4 | MFCD30496724 | 99.7% | 1097.37 | C56H80N12O9S | 25 MG
Ibrutinib-biotin is a biotinylated probe in which the BTK inhibitor ibrutinib is linked to biotin via a long-chain linker (derived from patent WO2014059368A1 Compound 1-5). It is intended for research use to study Bruton's tyrosine kinase (BTK) binding, target engagement, and affinity-based assays.
- Biotinylated probe for affinity capture and target engagement studies.
- High potency against BTK with IC50 of 0.755-1.02 nM.
- High purity (99.66%) suitable for biochemical and cellular assays.
- Available in small quantities for assay development (25 mg).
- Includes downloadable datasheet, COA, and SDS for experimental reproducibility.