Biotin and derivatives

Medchemexpress LLC Biotin-Ahx-angiotensin II human | 115102-72-2 | 100.0% | 1385.63 g/mol | C66H96N16O15S | 5 MG

Biotin-Ahx-Angiotensin II human is a biotin-labeled peptide based on the human angiotensin II sequence, modified with an aminohexanoic acid spacer and provided as a lyophilized powder for research use. It is designed for biochemical and receptor-binding studies where a biotin tag enables affinity capture or detection using streptavidin-based methods.

• Biotin tag enables streptavidin-based capture and detection.
• Aminohexanoic acid spacer helps preserve biological activity and accessibility.
• Sequence corresponds to human angiotensin II for receptor-binding studies.
• Supplied as a powder for convenient storage and handling.
• High purity suitable for biochemical and binding assays.

Apexbio Technology LLC Azidobutyric acid NHS ester 50mg

Azidobutyric acid NHS ester is a chemical reagent used to introduce azide functional groups onto biomolecules containing primary amines It is designed to enable the covalent modification of proteins peptides or amino-modified nucleotides facilitating subsequent copper-catalyzed azide-alkyne click chemistry reactions Azidobutyric acid NHS ester exerts its utility by forming stable amide bonds with amino groups under mild aqueous conditions thus providing an azide handle for bioorthogonal labeling Based on these properties Azidobutyric acid NHS ester holds research potential in applications such as bioimaging flow cytometry protein profiling affinity purification and drug conjugation research

Medchemexpress LLC ATRA-biotin (biotin-ATRA-conjugate) | 2226143-93-5 | 98.4% | 625.90 | C36H55N3O4S | 5 MG

ATRA-biotin is a biotin-conjugated derivative of all-trans retinoic acid designed to track ATRA localization and interactions in cells and tissues. The biotin moiety permits detection and affinity capture using streptavidin/avidin reagents, facilitating imaging, pull-down, and binding studies. The compound is supplied at high reported purity and includes documentation for characterization and safe handling.

• Biotin tag enables streptavidin-based detection and affinity capture.
• Suitable for tracking ATRA localization in cells and tissue samples.
• High reported purity supports biochemical and cell-based assays.
• Available in multiple pack sizes for scalability of experiments.
• Provided with datasheet, COA, and SDS for characterization and safety.

Medchemexpress LLC Biotin-Ahx-angiotensin II (human) | 115102-72-2 | 100.0% | C66H96N16O15S | 10MG

Biotin-Ahx-Angiotensin II (human) is a biotinylated octapeptide derived from angiotensin II, provided as a lyophilized powder for use as an affinity probe in biochemical and receptor-binding assays. The biotin tag attached via an aminohexanoic acid (Ahx) spacer enables streptavidin-based capture or detection while maintaining the peptide's biological activity. Molecular formula C66H96N16O15S; molecular weight 1385.63.

• Biotin tag for streptavidin-based detection and capture.
• Ahx spacer reduces steric hindrance and preserves peptide activity.
• Sequence corresponds to human angiotensin II for biologically relevant assays.
• High purity for consistent and reproducible results.
• Lyophilized powder format for long-term storage and easy reconstitution.

Apexbio Technology LLC Biotin-11-dUTP(Synonyms: Biotin-11-deoxyuridine triphosphate, Biotin-11-dUTP lithium salt), 10ul (5 mM), CAS: 1221498-88-9.

Biotin-11-dUTP (CAS 1221498-88-9) is a biotin-conjugated analogue of deoxythymidine triphosphate (dTTP) that can be incorporated enzymatically into DNA or cDNA sequences during polymerase reactions After integration labeled nucleic acid fragments can be detected using streptavidin coupled to horseradish peroxidase (HRP) alkaline phosphatase (AP) fluorescent molecules or bead-based capture systems This approach is frequently utilized in polymerase chain reaction (PCR) nick translation reverse transcription assays and apoptosis studies facilitating DNA probe labeling and molecular analysis workflows

Apexbio Technology LLC Biotin-11-dUTP(Synonyms: Biotin-11-deoxyuridine triphosphate, Biotin-11-dUTP lithium salt), 200ul (5 mM), CAS: 1221498-88-9.

Biotin-11-dUTP (CAS 1221498-88-9) is a biotin-conjugated analogue of deoxythymidine triphosphate (dTTP) that can be incorporated enzymatically into DNA or cDNA sequences during polymerase reactions After integration labeled nucleic acid fragments can be detected using streptavidin coupled to horseradish peroxidase (HRP) alkaline phosphatase (AP) fluorescent molecules or bead-based capture systems This approach is frequently utilized in polymerase chain reaction (PCR) nick translation reverse transcription assays and apoptosis studies facilitating DNA probe labeling and molecular analysis workflows

Medchemexpress LLC Biotin-ATRA-conjugate | 2226143-93-5 | 98.4% | C36H55N3O4S | 10MG

ATRA-biotin (biotin-ATRA-conjugate) is a biotin-labeled derivative of all-trans retinoic acid used as a tracer and affinity reagent to track ATRA distribution and interactions in biological samples. It supports biotin-streptavidin workflows and is supplied at high purity for research use only.

• Biotin tag enables streptavidin-based detection.
• Suitable for localization studies in cells and tissues.
• Compatible with pull-down and affinity capture assays.
• High purity for reproducible experimental results.
• Available in multiple laboratory-friendly pack sizes.

Medchemexpress LLC Cancer antigen 125 (MUC16), recombinant human, biotinylated | >95.0% | 50UG

Recombinant human CA125 (MUC16) is a biotinylated protein fragment (~685 amino acids) produced in HEK293 cells with C-terminal His and Avi tags. It is intended for binding studies, assay development, and detection workflows that use biotin-streptavidin capture.

• Biotinylated for streptavidin-based capture and detection.
• Expressed in HEK293 cells to provide mammalian glycosylation.
• C-terminal His and Avi tags for purification and site-specific biotinylation.
• Supplied at laboratory quantity suitable for assay development.
• High purity as determined by reducing SDS-PAGE (>95%).
• Molecular weight range 90-140 kDa reflecting glycosylated forms.

Medchemexpress LLC Biotin-PEG3-acid 1g | 252881-76-8 | 447.55 | C19H33N3O7S | 1 G

Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker used to introduce a biotin tag with a short PEG3 spacer in PROTAC synthesis and bioconjugation workflows. The material is supplied as a 1 g purified solid (typical purity 98.0%) with molecular weight 447.55 g/mol and chemical formula C19H33N3O7S, and is accompanied by a batch-specific certificate of analysis.

• Provides a biotin handle separated by a PEG3 spacer to reduce steric hindrance
• Designed for incorporation into PROTACs and other bioconjugates
• Improves aqueous solubility compared with direct biotinylation
• Typically supplied with batch certificate showing ~98.0% purity
• Solid form with known molecular weight and formula for formulation planning

Apexbio Technology LLC Biotin Hydrazide 66640-86-6 500mg

Biotin hydrazide is a hydrazide-functionalized biotin derivative designed to selectively label and detect protein carbonylation an irreversible post-translational modification frequently arising from oxidative stress conditions Protein carbonylation typically results from reactions between protein side chains and reactive oxygen species (ROS) lipid peroxidation metabolites such as -unsaturated -hydroxyalkenals or glycation-mediated oxidative modifications Mechanistically Biotin Hydrazide interacts specifically with protein-bound carbonyl groups through hydrazone formation under mildly acidic conditions (around pH 5 5) without the requirement of additional reducing agents or catalysts Thus Biotin hydrazide facilitates biochemical studies aimed at identifying and characterizing carbonyl-modified proteins in biological samples through biotin-based detection assays and downstream proteomic analysis techniques