Cycloheptathiophenes
Medchemexpress LLC Ocifisertib fumarate | 1616420-30-4 | >98.0% | 650.7 g/mol | C37H38N4O7 | 50MG
Ocifisertib fumarate is the fumarate salt of CFI-400945, a potent, selective, and orally bioavailable inhibitor of polo-like kinase 4 (PLK4) supplied for research use in biochemical and cellular studies of PLK4-related pathways and antineoplastic activity.
- Fumarate salt form of the PLK4 inhibitor.
- Potent biochemical activity: PLK4 Ki = 0.26 nM; PLK4 IC50 = 2.8 nM.
- Molecular formula C37H38N4O7 and molecular weight 650.7 g/mol.
- High purity (>98.0% by HPLC) suitable for research applications.
- Supplied in small research pack sizes, including 50 mg.
Medchemexpress LLC Ocifisertib (fumarate) | 1616420-30-4 | 99.3% | 650.72 g/mol | C37H38N4O7 | 10MG
Ocifisertib fumarate is the fumarate salt of CFI-400945, an orally bioavailable small-molecule inhibitor of Polo-like kinase 4 (PLK4) for preclinical research. It is supplied as a powder for in vitro and in vivo studies and shows low-nanomolar potency against PLK4 and activity against several related kinases.
Medchemexpress LLC Monomethyl fumarate-d2 | 253122-44-0 | MFCD00063174 | 98.2% | 132.11 | C5H4D2O4 | 1 MG
Monomethyl fumarate-d2 is the deuterium-labeled form of monomethyl fumarate, provided as a high-purity research chemical and isotopically labeled standard for metabolic, pharmacological, and analytical studies.
- Deuterium-labeled analog for isotope tracing and mass spectrometry.
- High purity suitable for research applications.
- Supplied in milligram quantities for small-scale experiments.
- Useful as a metabolic standard and mechanistic probe.
Selleck Chemical LLC Clemastine fumarate S1847-1g
Clemastine fumarate is a selective histamine H1 receptor antagonist with IC50 of 3 nM Clemastine stimulates autophagy via mTOR pathway
Apexbio Technology LLC Clemastine Fumarate 14976-57-9 500mg
Clemastine Fumarate (CAS 14976-57-9) is a small molecule that functions as a selective antagonist of the histamine H1 receptor It demonstrates high affinity for the receptor with an inhibitory concentration (IC50) of 3 nM By blocking histamine H1 receptor-mediated signaling clemastine fumarate is utilized in research to study histaminergic pathways and allergic responses It is also employed to investigate the pharmacological modulation of H1 receptor activity in various cellular and in vivo models
Apexbio Technology LLC Dimethyl Fumarate 624-49-7 5g
Dimethyl fumarate (CAS 624-49-7) is a small-molecule activator targeting the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway It is designed to promote Nrf2 nuclear translocation and induce transcription of antioxidant response genes thereby modulating oxidative stress response pathways Dimethyl fumarate exerts its biological activity primarily through activation of Nrf2-mediated antioxidant gene expression In cell-based assays dimethyl fumarate demonstrates Nrf2 activation activity with an IC50 value of approximately 5 M Based on these pharmacological properties dimethyl fumarate holds research potential in the study of oxidative stress inflammation and related pathophysiological processes
Medchemexpress LLC Fumarate hydratase-I 10mM 1mL
Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2 2 M1]
Medchemexpress LLC Ro60-0175 fumarate | 169675-09-6 | MFCD06798313 | 99.5% | 342.75 g/mol | C15H16ClFN2O4 | 1 ML
Ro60-0175 fumarate is a selective agonist of the serotonin 5-HT2C receptor used in neuroscience and pharmacology research. It is provided as a ready-to-use 10 mM solution in DMSO (1 mL) and in solid quantities; reported purity is 99.47%, with molecular formula C15H16ClFN2O4 and molecular weight 342.75 g/mol.
- Selective 5-HT2C receptor agonist for pharmacology studies.
- Available as 10 mM solution in DMSO (1 mL) and as solids (5, 10, 50 mg).
- High purity (~99.5%) suitable for research applications.
- Soluble in DMSO; in vitro solubility approximately 100 mg/mL.
- Storage guidance provided for powder and solutions to preserve stability.
Selleck Chemical LLC Ketotifen Fumarate S2024-50mg
Ketotifen Fumarate(HC 20511 fumarate) is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer
Enzo Life Sciences Ketotifen. fumarate (1g). CAS: 34580-14-8
Selective histamine H1 antagonist. Inhibits histamine release from monocytes and lymphocytes at 0.1-10 µM. Purity: ≥98% (HPLC). Solubility: Soluble in water (10 mg/ml). Long Term Storage: Ambient.
Medchemexpress LLC Zamifenacin fumarate | 127308-98-9 | 99.0% | 531.60 g/mol | C31H33NO7 | 1 ML
Zamifenacin fumarate is a gut-selective muscarinic M3 receptor antagonist provided for research use. It reduces colonic motility and is commonly used in pharmacology studies of muscarinic receptor function. The compound is available as a solid or as pre-made DMSO solution (typical 10 mM, 1 mL), with reported purity around 99.0% and molecular weight 531.60 g/mol.