Cycloheptathiophenes
Ketotifen fumarate, 99%
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
![Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%](https://assets.fishersci.com/TFS-Assets/CCG/Chemical-Structures/chemical-structure-cas-40106-13-6.jpg-250.jpg)
Ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate, 96%
CAS: 40106-13-6 Molecular Formula: C12H17NO2S Molecular Weight (g/mol): 239.333 MDL Number: MFCD00216932 InChI Key: XTUHIGALMIGZST-UHFFFAOYSA-N Synonym: ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-4h,5h,6h,7h,8h-cyclohepta b thiophene-3-carboxylate,ethyl 2-amino-5,6,7,8-tetrahydro-4h-cyclohepta-b thiophene-3-carboxylate,ethyl 2-amino-4,5,6,7,8-pentahydrocyclohepta 1,2-b thiophene-3-carboxylate,2-amino-5,6,7,8-tetrahydro-4h-cyclohepta b thiophene-3-carboxylic acid ethyl ester,ethyl 2-aminocyclohepta b thiophene-3-carboxylate,aronis24232,ethyl 2-aminocycloheptathiophene-3-carboxylate,2-amino-3-ethoxy-carbonyl-4,5-pentamethylenethiophene PubChem CID: 292644 IUPAC Name: ethyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate SMILES: CCOC(=O)C1=C(SC2=C1CCCCC2)N
Ketotifen Hydrogen Fumarate, EP, 98.5-101%, Spectrum™ Chemical
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.50 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N IUPAC Name: (2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one SMILES: OC(=O)\C=C\C(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
Pizotifen 98.0+%, TCI America™
CAS: 15574-96-6 Molecular Formula: C19H21NS Molecular Weight (g/mol): 295.444 MDL Number: MFCD00864192 InChI Key: FIADGNVRKBPQEU-UHFFFAOYSA-N Synonym: 4-[9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene]-1-methylpiperidine, Sandomigran PubChem CID: 27400 ChEBI: CHEBI:50212 IUPAC Name: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine SMILES: CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1
Ketotifen Fumarate 98.0+%, TCI America™
CAS: 34580-14-8 Molecular Formula: C23H23NO5S Molecular Weight (g/mol): 425.499 MDL Number: MFCD00079394 InChI Key: YNQQEYBLVYAWNX-WLHGVMLRSA-N Synonym: ketotifen fumarate,zaditen,ketotifen hydrogen fumarate,alaway,unii-hbd503woro,hc 20,511 fumarate,ketotifen fumarate usan:jan,ketotifen fumarate salt,hbd503woro PubChem CID: 5282408 IUPAC Name: (E)-but-2-enedioic acid;10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one SMILES: CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=CC(=O)O)C(=O)O
Medchemexpress LLC Formoterol fumarate | 43229-80-7 | >99.9% | C19H24N2O4 . 1/2C4H4O4 | 100 MG
Formoterol fumarate is a selective β2-adrenoceptor agonist, at least as selective as Salbutamol and Terbutaline. It relaxes acetylcholine-pre-contracted human isolated segmental bronchi and can be used for research related to chronic obstructive pulmonary disease and bronchial asthma.
- Selective β2-adrenoceptor agonist
- Relaxes acetylcholine-pre-contracted human isolated segmental bronchi
- Suitable for research on chronic obstructive pulmonary disease
- Suitable for research on bronchial asthma
Selleck Chemical LLC Fumarate hydratase-IN-1
Fumarate hydratase-IN-1 is a small molecule cell-permeable inhibitor of fumarate hydratase It induce alteration of TCA cycle metabolites modulation of cytosolic processes and substantial redox stress responses
Medchemexpress LLC Dimethyl fumarate | 624-49-7 | 100.0% | 144.13 | 1 ML
Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator that induces upregulation of antioxidant gene expression. It also induces necroptosis in colon cancer cells via the GSH depletion/ROS increase/MAPKs activation pathway, and promotes cell autophagy. Dimethyl fumarate is used for multiple sclerosis research.
- Orally active and brain-penetrant Nrf2 activator
- Induces upregulation of antioxidant gene expression
- Induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway
- Promotes cell autophagy
- Used for multiple sclerosis research
Selleck Chemical LLC Ferrous fumarate
Ferrous fumarate (Iron(II)) is the fumarate salt form of the mineral iron and is used in treatment of iron deficiency anemia
Apexbio Technology LLC Ketotifen Fumarate 34580-14-8 200mg
Ketotifen fumarate is a noncompetitive antagonist of histamine H1 receptors and functions additionally as a mast cell stabilizer It inhibits histamine-mediated allergic responses through preventing histamine receptor activation and limiting mast cell degranulation Its pharmacological activity involves suppression of calcium influx into mast cells thus inhibiting histamine release Ketotifen fumarate is extensively utilized in biomedical research focusing on allergy and asthma pathophysiology to assess mast-cell-mediated mechanisms and histamine signaling pathways In vitro studies report its IC50 values ranging approximately from 0 8 to 2 5 M depending on assay parameters and cell types This compound commonly serves as a pharmacological tool when investigating allergic inflammation asthma and histamine-dependent cellular events
Medchemexpress LLC Crozbaciclib fumarate | 2567494-39-5 | 99.4% | 604.65 | 10 MG
Crozbaciclib fumarate is a potent CDK4/6 inhibitor, demonstrating significant anti-proliferative effects by arresting the U87MG cell line exclusively in G1. It has shown promising results in vivo, including substantial tumor growth inhibition in orthotopic xenograft mouse models of glioblastoma multiforme.
- Potent CDK4/6 inhibitor with IC50s of 3 nM (CDK4) and 1 nM (CDK6).
- Acts as an anti-proliferative agent, arresting U87MG cells in G1.
- Exhibits tumor growth inhibition from 62% to 99% in glioblastoma multiforme xenograft models.
- Increases lifespan by 162% in mice at a dose of 50 mg/kg.
Medchemexpress LLC Diroximel fumarate | 1577222-14-0 | 99.9% | 255.22 g/mol | C11H13NO6 | 1 ML
Diroximel fumarate is an orally active prodrug of monomethyl fumarate used in preclinical research to probe Nrf2 pathway modulation and multiple sclerosis-related biology. Supplied as a ready-to-use solution, it is intended for laboratory research use only and not for human or clinical applications.
- Ready-to-use 10 mM solution in DMSO for immediate experimental use.
- High purity (99.90%) suitable for biochemical and cellular assays.
- Molecular weight 255.22 g/mol, molecular formula C11H13NO6.
- Prodrug of monomethyl fumarate for Nrf2 pathway and MS-related research.
- Provided in a 1 mL volume for small-scale assays and dose-response studies.
- For research use only; not for human or clinical use.
Medchemexpress LLC Formoterol fumarate | 43229-80-7 | 99.8% | C19H24N2O4·1/2C4H4O4 | 50 MG
Formoterol fumarate is a selective β2-adrenoceptor agonist. This compound abolishes contraction induced by Acetylcholine in bronchioles and can be utilized for research into chronic obstructive pulmonary disease and bronchial asthma.
- Selective β2-adrenoceptor agonist
- Abolishes contraction induced by Acetylcholine in bronchioles
- Can be used for research of chronic obstructive pulmonary disease and bronchial asthma
- Appears as a white to off-white solid
- Soluble in DMSO at ≥ 50 mg/mL
Medchemexpress LLC 2-Butenedioic acid (2E)-, 1,4-diethyl ester | 623-91-6 | 99.0% | 172.18 | 10 MM/ML
Diethyl fumarate (Standard) is the analytical standard of Diethyl fumarate. This product is intended for research and analytical applications. It is a decomposition product of Malathion 9 (a pesticide) and a reactant in the Diels-Alder reaction. It is a reputed skin irritant and can cause non-immunologic contact urticaria on skin. Diethyl fumarate and Curcumin hybridize to exert neuroprotective effects.
- Serves as an analytical standard and reference standard supplied assay.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Reactant in the Diels-Alder reaction.
- Exerts neuroprotective effects when hybridized with Curcumin.